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Binding studies were carried out in which heparin was immobilized on the surface of cuvettes. The pH dependence of HPRG binding to heparin was investigated and the results are shown in Figure.
a. How is the binding of HPRG to heparin dependent on pH? Give structural reasons for the binding dependence. The structure of heparin is shown in Figure
2.2. NOTE: Figure also serves as a titration curve for the His residues in HPRG-what is the pKR for these residues? Explain.
b. The same binding studies were carried out in which HPRG was reacted with diethylpyrocarbonate (DEPC), a compound that specifically reacts with histidine residues. The reaction is shown in figure. Explain the results.
Amount to be provided for retirement of long-term obligations An “other debit” common journal value used in the General Long-Term Bills Additional Consideration that symbolizes t
S&V Industries manufactures book cases. Different sizes of cases are kept in inventory. The company has 80 man-hours and 36 pounds of wood available each day. 2 pounds of wood are
i) For a 3 term averagin filter, write a difference eqatuon governing the filter and dervie the corresponding z transform Sketch a pole zero plot, would this filter be stable, why
1 . Below are the points scored by the winning team in Week 10 of NFL professional football games this Fall, 2011. 24 17 44 13 21 24 30 20 37 26 17 22 27 37 37 45 a) Use thes
assignment.
costing and control of overheads
regression line drawn asY=C+1075x,when x was 2,and y was239,given that y intercept was11.calculate the residual.
merits and demerits of arithmetic mean
The poll interviewed 1500 persons rather than 1060, for 95% confidence.
In a survey of 284 smokers, 197 smokers reported that they wanted to quit smoking. Compute a 90% confidence interval for the true proportion of smokers that want to quit smoking.
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