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Gene targeting: There is always a debate on gene integration in to the host animal.
It is random gene integration Vs gene targeting. Perhaps most significantly, pro-nuclear injection cannot be used to modify the animals' own genes. By contrast, target modifications to endogenous genes have been achieved earlier in mouse model and now in farm animals also. When introduced into the early embryo these cells contribute to the germline. They can also undergo homologous recombination with transfected foreign DNA so that precise, targeted changes can be introduced. The combination of these two properties means that gene targeting of the mouse germline is now routine, allowing for the deletion, replacement or modification of selected genes. Recombination on either side of the marker gene results in its precise insertion into the chromosome at the same time and delete some or the entire target gene. Precise targeting events are very rare (perhaps 1 in 106 cells) and, therefore special methods must be taken for identifying and selecting the correctly targeted cells.
Q. What are the effects of somatostatin for the pancreatic hormonal secretion? Somatostatin inhibits both glucagon and insulin secretions.
The aqueous fluid that fills the nuclear region is known as karyolymph, or nucleoplasm. In the fluid there are proteins, enzymes and other significant substances for the nuclear me
What is the relevance of knowing about GI of foods? Let us see how this index is helpful in prescribing therapeutic diets. You would realize that the dietary GI provides an ind
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What is Left Ventricular Hypertrophy (LVH) ? LVH develops as the response of the heart to chronic pressure or volume overload and is defined as a left ventricular mass exceedin
explain the role of cyclic photophosphorylation in photosynthesis
Female Gametophyte The development of a female gametophyte is initiated with the enlargement of one of the megaspores (usually the one close to the chalaza in a linear tetrad)
Mixed Mitral Stenosis and Regurgitation The most common cause for a combined lesion is rheumatic, Very rarely; it could be of congenital origin. Regurgitation in a stenotic val
Silver point extended below canal orifice - Ultra-sonic tip - Microtube tape: The post removal system (PRS) Trephine bur Masserann kit - Do trimming by
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