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Gene targeting: There is always a debate on gene integration in to the host animal.
It is random gene integration Vs gene targeting. Perhaps most significantly, pro-nuclear injection cannot be used to modify the animals' own genes. By contrast, target modifications to endogenous genes have been achieved earlier in mouse model and now in farm animals also. When introduced into the early embryo these cells contribute to the germline. They can also undergo homologous recombination with transfected foreign DNA so that precise, targeted changes can be introduced. The combination of these two properties means that gene targeting of the mouse germline is now routine, allowing for the deletion, replacement or modification of selected genes. Recombination on either side of the marker gene results in its precise insertion into the chromosome at the same time and delete some or the entire target gene. Precise targeting events are very rare (perhaps 1 in 106 cells) and, therefore special methods must be taken for identifying and selecting the correctly targeted cells.
TRISACCHARIDES The oligosaccharides are made of three monosaccharide residues. A common trisaccharides is Raffinose which is formed by condensation of galactose-glucose-fr
Q. What is the major transformation presented by the glomerular filtrate in comparison to the blood? Glomerular filtrate is the name given to the plasma after it has entered th
what does cuticle mean
Q. What is the coelom? To which structures do coeloms give birth? Are all animals coelomate? Coeloms are cavities delimited by mesoderm and Coeloms originate the cavities where
Cleavage of fructose-1,6-bisphosphate Aldolase cleaves fructose-1, 6-bisphosphate to dihydroxyacetone phosphate and glyceraldehyde-3-phosphate in the reversible reaction.
Discuss six bad listening habits. Which do you think is the biggest challenge for you personally?
V i ra l Diseases A v ian encephalomyelitis This is enterovirus disease of chicken, pheasants, turkeys and Japanese quails caused by the member of the family Pi
Prostaglandins Prostaglandins belong to a subclass of lipids known as the eicosanoids because of their structural similarities to the C-20 polyunsaturated fatty acids, t
What are the principal sources of excessive nitrate and phosphate in rivers and lakes?
how the optical rotaion occurs in glucose and ribose?
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