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Gene targeting: There is always a debate on gene integration in to the host animal.
It is random gene integration Vs gene targeting. Perhaps most significantly, pro-nuclear injection cannot be used to modify the animals' own genes. By contrast, target modifications to endogenous genes have been achieved earlier in mouse model and now in farm animals also. When introduced into the early embryo these cells contribute to the germline. They can also undergo homologous recombination with transfected foreign DNA so that precise, targeted changes can be introduced. The combination of these two properties means that gene targeting of the mouse germline is now routine, allowing for the deletion, replacement or modification of selected genes. Recombination on either side of the marker gene results in its precise insertion into the chromosome at the same time and delete some or the entire target gene. Precise targeting events are very rare (perhaps 1 in 106 cells) and, therefore special methods must be taken for identifying and selecting the correctly targeted cells.
What is Intra oral and Extra Oral A) Intra oral a) Frontal in occlusion b) Left and right occlusion (Using intra oral photography mirror) c) Occlusal view maxillary
Galactose Metabolism Galactose goes to the liver via portal blood and is phosphorylated by galactokinase togalactose- 1 -phosphate (GIP) using ATP as a phosphate donor as s
Budding - Types of Asexual Reproduction In reproduction through budding, small groups of cells form buds in some part or parts of the parent animal. The bud grows, differentia
Neonatal hypoglycaemia Hypoglycaemia is a metabolic condition of newborn piglets that develops in first few days of life due to decreased caloric intake and increased cataboli
Active transport is the transport of the molecules against the concentration gradient (from area of low concentration to area of high concentration) with the help of proteins in t
Associated nerves and vessels The Anterior superior alveolar, Infraorbital, and Posterior superior alveolar nerves and arteries provide both the innervation and blood supply to
How do you increase your BMR?
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EXPLAIN IN DETAILS FEEDING MECHANISM IN MAN.
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