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Gene targeting: There is always a debate on gene integration in to the host animal.
It is random gene integration Vs gene targeting. Perhaps most significantly, pro-nuclear injection cannot be used to modify the animals' own genes. By contrast, target modifications to endogenous genes have been achieved earlier in mouse model and now in farm animals also. When introduced into the early embryo these cells contribute to the germline. They can also undergo homologous recombination with transfected foreign DNA so that precise, targeted changes can be introduced. The combination of these two properties means that gene targeting of the mouse germline is now routine, allowing for the deletion, replacement or modification of selected genes. Recombination on either side of the marker gene results in its precise insertion into the chromosome at the same time and delete some or the entire target gene. Precise targeting events are very rare (perhaps 1 in 106 cells) and, therefore special methods must be taken for identifying and selecting the correctly targeted cells.
What is tubal pregnancy? Many times fecundation takes place in the Fallopian tubes. Usually the newly formed zygote is taken to the uterus where nidation and the embryonic deve
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Define Principle for Estimation of cholesterol - Lipids? Zlatkis and associates have evolved a method of quantitative determination of cholesterol based on a reagent containing
Q. Explain about Glycemic Index? Although the use of exchange lists is still popular for planning diabetic diets, it has been realized in recent years that in exchange lists th
I need the parts of the structure carbon. Include elements,monomer,polymer, and any sub units
how do work in human body and animals
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A zoologist is investigating a population of squirrels whose coat color is controlled by a single gene whose two alleles (B1 & B2) are codominant. B1B1 individuals are black, B1B2
Options with Rifampin Standard 4-drug treatment regimens including rifampin can be given to HIV-infected patients with active TB who are simultaneously receiving HAART if the H
Foot examination For all diabetics, foot examination is important and necessary in all visits to identify risk factors of ulcers or injury of foot. This will help in preventing
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