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Gene targeting: There is always a debate on gene integration in to the host animal.
It is random gene integration Vs gene targeting. Perhaps most significantly, pro-nuclear injection cannot be used to modify the animals' own genes. By contrast, target modifications to endogenous genes have been achieved earlier in mouse model and now in farm animals also. When introduced into the early embryo these cells contribute to the germline. They can also undergo homologous recombination with transfected foreign DNA so that precise, targeted changes can be introduced. The combination of these two properties means that gene targeting of the mouse germline is now routine, allowing for the deletion, replacement or modification of selected genes. Recombination on either side of the marker gene results in its precise insertion into the chromosome at the same time and delete some or the entire target gene. Precise targeting events are very rare (perhaps 1 in 106 cells) and, therefore special methods must be taken for identifying and selecting the correctly targeted cells.
Define Calamity and Emergency Management - nutritional needs of humans? During past many years, we have seen, as well as, realized -that natural calamities strikes countries, b
What is Quantitative Techniques? Microbial quality of substances like food, milk, air, water, soil etc. can be assessed both qualitatively and quantitatively. Quantitative enum
how connective tissues are like an estuary
What is the inactivation of the X chromosome? What is a Barr body? Inactivation of the X chromosome is a phenomenon that happens in women. As women have two X chromosomes only
What are the uses of formycin B? Formycin B is a drug used to demolish of intestinal parasites.
Non-recurrent Type As mentioned earlier it refers to embryo development in reduced embryo sacs. The mechanisms identified for such cases are: Reduced Pseudogamy : The
Do octopus and squids have exoskeleton? Octopus and squids normally do not produce external shell (some squid species can have an internal shell). One cephalopod group, the nau
Modern Biology Increasing advancement in biotechnology has brought about a veritable explosion of Biological knowledge since early 1950s.This vast modern biological information
what is the structure of hiv virus?
A glycogen molecule having entirely of glucose units, many of that are linked in long chains through α1-4 bonds. Furthermore, every 10 units or so, the chain is branched
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