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Gene targeting: There is always a debate on gene integration in to the host animal.
It is random gene integration Vs gene targeting. Perhaps most significantly, pro-nuclear injection cannot be used to modify the animals' own genes. By contrast, target modifications to endogenous genes have been achieved earlier in mouse model and now in farm animals also. When introduced into the early embryo these cells contribute to the germline. They can also undergo homologous recombination with transfected foreign DNA so that precise, targeted changes can be introduced. The combination of these two properties means that gene targeting of the mouse germline is now routine, allowing for the deletion, replacement or modification of selected genes. Recombination on either side of the marker gene results in its precise insertion into the chromosome at the same time and delete some or the entire target gene. Precise targeting events are very rare (perhaps 1 in 106 cells) and, therefore special methods must be taken for identifying and selecting the correctly targeted cells.
justify the claim that paramecium is the highly evolved protozoan basing on the morphological and physiological features .
All the cells present in the body contain genes and an approach targeted to modulate the expression of genes is known as gene therapy. This novel approach has emerged by the end of
Cytokinesis in an animal cell: Splitting of the cell is called cytokinesis which starts at telophase. In animal cells, microtubules form a furrow in a ring around the cell.
Define Role of Iron in Controlling Gene Expression? Iron metabolism is regulated by a complex co-ordinate mechanism. Recent evidence supports specific past-transcriptional mech
Theories are import because they can be used to a. Test research hypothesis b. Develop questions which will facilitate more effective research c. Conduct more meaningful and useful
Explain about the Parkinson's disease? Parkinson's disease is a degenerative central nervous system (CNS) condition characterized by progressive loss of cells within substantia
Applications of Biotin Biotin is mainly used in the preparation of injection, and also in the manufacture of vitamin B complex and multi-vitamin preparations. It is used in
what is virus ?? what is classidication , uses , disease of viruses ? what are types of virus ?
Q. What are sarcomeres? Sarcomeres are the contractile units of the muscle tissue formed of alternating myosin blocks (thick filaments) and actin blocks (thin filaments). Sever
D uck septicemia (duck pasteurellosis/new duck disease) The disease is caused by Pasteruella anatipestifer (Syn. Riemerella anatipestifer ) that mostly affects growing duck
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