Already have an account? Get multiple benefits of using own account!
Login in your account..!
Remember me
Don't have an account? Create your account in less than a minutes,
Forgot password? how can I recover my password now!
Enter right registered email to receive password!
Gene or point mutations occur when the DNA sequence of a gene is altered and the new nucleotide sequence is passed on to the offspring. This occurs either due to addition or deletion or substitution of one or a few nucleoticles. Nucleotide substitutions can be either transitions or transversions. Transitions are replacements of a purine by another purine (A by G or vice versa) or a pyrimidiile by another pyrimidine (C by T or vice versa). Transversions are replacements of a purine by the pyrimidine or vice versa (G or A by C or T or vice versa). We will briefly explain the different types of gene mutations.
a) Substitutions : substitution of one base by another would result in an altered amino acid in a polypeptide chain. For instance triplet AAT in DNA (UUA in mRNA) would specify leucine. But if the first A is ieplaced by C, it will code for valine. Some of the codons are degenerate and substitutions may not alter the amino acid specified. For instance, in the triplet AAT if the first A is replaced by G the amino acid coded would still be leucine. Gene mutations which do not normally affect the active site of a protein will not alter its biological functions. But nucleotide substitutions that change a triplet coding lor an amino acid into a termination codon would produce adverse effects. Once again in AAT, if the second A is replaced hy T (An), the resulting rnRNA codon IJAA is a termination codon. When a termination codon is present in the middle of an mRNA molecule the subsequent codons are not translated and an incomplete polypeptide will be released from ribosomes.
What are some mechanisms by which pathogenic bacteria cause diseases? Why is this knowledge important? Pathogenic bacteria have characteristics called as virulence factors that
Adverse Effects of amantadine Amantadine may cause anorexia, nausea, peripheral edema and, particularly in the elderly, minor CNS effects such as nervousness, anxiety, insomn
Explain Re- pera at ions and Other Interventions ? These are required for residual VSD with significant shunt, residual RV obstruction and pulmonary valve regurgitation in a fe
What is sodium-potassium pump ATPase? A. There is a net flux of sodium from intracellular spaces into luminal spaces through sodium-potassium pump ATPase spanning proteins l
Determine the Modification of native starch Modification of native starch can be either physical or chemical. Chemical modification includes reaction of starch with acid or al
Q. Etiologic factor of atherosclerosis? Various factors are responsible for atherosclerosis. These include: 1. Hyperlipidemin: Excess circulating fats in blood especially th
What are risk factors for diseases? Risk factors for a disease are everything that contributes to enhance the risk of the disease to appear. For instance, for most cardiovascul
Preparation - Culture Medium Now that you are familiar with the constituents the preparation of medium is quite simple. Several plant tissue culture media are now available
What is Nervous System? The nervous system is made up of associations of cells called neurons. Bundles of neurons are called nerves. The nervous system is divided into two part
????? # 100 ??????????? #Minimum ?????? ?????
Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!
whatsapp: +91-977-207-8620
Phone: +91-977-207-8620
Email: [email protected]
All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd