Frailty, Advanced Statistics

Assignment Help:

A term usually used for unobserved individual heterogeneity. Such variation is of main concern in the medical statistics particularly in the analysis of the survival times where hazard functions can be strongly influenced by the selection effects operating in the population. There are several possible sources of this heterogeneity, the most apparent of which is that it reflects the biological differences, so that, for instance, some individuals are born with the weaker heart, or a genetic disposition for cancer. A further prospect is that the heterogeneity happens from the occured weaknesses which result from the stresses of life. Failure to take account of this kind of variation might often obscure comparisons between groups, for instance, by measures of relative risk. A simple model which attempts to permit for the variation between individuals is given as follows


1270_fraility.png 


where Z is the quantity specific to an individual, considered as the random variable over the population of individuals, and the base rate is denoted by λ(t) . What is observed in a population for which this type of model holds is not the individual hazard rate but the net result for several individuals with different values of Z.

 


Related Discussions:- Frailty

Linear regression assignment help, Using World Bank (2004) World Developmen...

Using World Bank (2004) World Development Indicators; Washington: International Bank for Reconstruction & Development/ The World Bank, located in the reference section of the Learn

Statistics, cholscores Treatment income ($000) Patient ID low Income? ...

cholscores Treatment income ($000) Patient ID low Income? 0.6 Old 21.3 2 Yes 0.17 Old 27.2 13 Yes 0.69 New 27.1 16 Yes 1.09 Old 94.8

Resentful demoralization, Resentful demoralization is the possible phenome...

Resentful demoralization is the possible phenomenon in the clinical trials and intervention studies in which comparison groups not attaining a perceived desirable treatment become

Historigram, difference between histogram and historigram

difference between histogram and historigram

Dirichlet process, The distribution over distributions in the sense that ea...

The distribution over distributions in the sense that each draw from the process is itself the distribution. The name Dirichlet process or procedure is due to the fact that the ?ni

Data reduction, The method of summarizing the large amounts of data by form...

The method of summarizing the large amounts of data by forming the frequency distributions, scatter diagrams, histograms, etc., and calculating statistics like means variances and

Regression, what are tests for residual with nonconstant variance in regres...

what are tests for residual with nonconstant variance in regression diagnostic checking?

Advanced managerial statistics, The objective of this assignment is to test...

The objective of this assignment is to test your understanding in the learning outcome (LO2) and learning outcome (LO3) and learning outcome (LO4). 1) This is a grouped assignme

T test , How do I report the results in the table?

How do I report the results in the table?

Correspondence analysis, The method or technique for displaying the relatio...

The method or technique for displaying the relationships between categorical variables in a type of the scatter plot diagram. For two this type of variables displayed in the form o

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd