Extracellular aging, Biology

Assignment Help:

Extracellular Aging

The basic components of extracellular space are mucopolysaccharides and fibrous proteins, particularly collagen and elastin. These proteins are synthesised in connective tissue and secreted out of the tissue. Collagen is predictable to form up to 40% of the body protein and fills the extracellular spaces. It has been recommended as the primary site of age related changes. Remember that collagen molecules are polymers of tropocollagen monomers. Newly polymerised molecules of collagen comprise non-covalent bonds and with age covalent cross-linking takes place between the monomers. Like the age of the organism increases cross-linking becomes much more hard to dissociate and by the time of maturity in mammals collagen becomes insoluble. From maturity to old age; cross-linking is strengthened and its effect can be computed. The age related changes in collagen are indisputable. Age related changes in the structure of collagen influence the functioning and structure of bones, tendon, blood vessels, joints, ligament etc. The inflexibility of collagen fibrils may be a contributory factor for the onset of atherosclerosis and hypertension.


Related Discussions:- Extracellular aging

Extinction of a plant species, How could humans be disadvantaged by the ext...

How could humans be disadvantaged by the extinction of a plant species? The loss of a plant species may deprive humans of any beneficial substances (e.g. drugs) that the specie

Explain non-nucleoside reverse transcriptase inhibitors, Non-nucleoside rev...

Non-nucleoside reverse transcriptase inhibitors (NNRTIs) - These drugs are direct, non-nucleoside inhibitors of HIV-1 reverse transcriptase. Combinations of an NNRTI with NRTIs

Events prior to the sperm-egg fusion, Events prior to the Sperm-Egg Fusion ...

Events prior to the Sperm-Egg Fusion In a number of organisms that have been studied, the sperm remain immotile in the testis or in the semen. The sperm become active and mot

Cranium, need images of cranium

need images of cranium

Explain the techniques of surgical correction , Explain  the Techniques of...

Explain  the Techniques of Surgical Correction ? Techniques of Surgical Correction proximal Dissection (De Bakey type I and IZ or Stanford A) Monitoring lines are insert

Explain about the weight imbalance, Explain about the Weight Imbalance? ...

Explain about the Weight Imbalance? You are aware that obesity is one of the major public health problems of the world, Earlier a problem of the developed nations; it is now in

What is the typical localization of the tropical forests, What is the typic...

What is the typical localization of the tropical forests regarding latitude? Tropical rain forests, as the Amazon forest and the Congo forest, are typically located in low lati

Transcription and processing of trna in prokaryotes , The rRNA transcriptio...

The rRNA transcription units in E. coli hold some tRNA genes which are processed and transcribed at the time of rRNA transcription. The other tRNA genes  happen  in  clusters  of

What are the types of good in the demand curve, What are the types of good ...

What are the types of good in the demand curve? Some types of good are as follows: • Normal good: When incomes of consumers/households increase the quantity demanded wo

What is an example of an ion of biological importance, What is an example o...

What is an example of an ion of biological importance? Sodium in one, but so are potassium and calcium

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd