Exstrophy of the bladder, Biology

Assignment Help:

Exstrophy of the Bladder

This is the most common major congenital defect of lower urinary and genital tract. This is found more frequently in males than in females.

Exstrophy of bladder results when an abnormally large cloacal membrane prevents mesodermal growth and lower abdominal midline fusion. When the cloacal membrance ruptures the anterior abdominal wall, pubis, bladder and urethra fail to develop normally. The paired original tissues of the penis or clitoris fail to fuse in the midline.

In complete extrophy the entire bladder to the external urethral meatus is exposed and may be without ventral covering and this may be accompanied with epispadias, undesceded testes or inguinal hernia.

Incidence

It occurs approximately in 40,000 deliveries.

Pathophysiology

It results from failure of the abdominal wall and its under lying structures to fuse in utero. The anterior surface of the bladder lies open on the lower part of abdomen allowing constant passage of urine to out side. Management includes surgical closure of bladder in 48 hours. Complete correction by school age. Also urinary diversion may be done in some cases.


Related Discussions:- Exstrophy of the bladder

Class polychaeta - classification of coelom, Class Polychaeta - Classificat...

Class Polychaeta - Classification of Coelom There are mainly marine forms with distinct head, having eyes and tentacles, segments have lateral projections of the body wall ter

How does the male gamete penetrate the egg cell, Q. How does the male gamet...

Q. How does the male gamete penetrate the egg cell? How does the female gamete protect itself from the entrance of more gametes after the entrance of the first sperm cell? The

Freshwater animals, Freshwater Animals In Figure you have seen that th...

Freshwater Animals In Figure you have seen that the body fluids of freshwater animals are hyperosmotic to their aqueous surroundings. This results in two-kinds of osmotic prob

Enlist the modalities available for hand wash, Q. Enlist the modalities ava...

Q. Enlist the modalities available for hand wash? Modalities available for hand wishing are a) 2-4% Chlorhexidine b) 0.3-1 %Triclosan c) 0.6% Parachlorometaxylenol (PC

Advanced nervous systems - general trend in evolution, Advanced Nervous Sys...

Advanced Nervous Systems - General Trend In Evolution In higher groups of animals you will observe clear trends towards centralisation of the nervous system, to maximize effe

Respiratory chain to produce atp, Decreasing power is available in a cell b...

Decreasing power is available in a cell both as NADPH and NADH but these have quite distinct roles. NADH is oxidized by the respiratory chain to produce ATP by oxidative phosphoryl

Explain the presumptive test - most probable number test, Explain the Presu...

Explain the Presumptive Test - Most Probable Number Test? The Presumptive test is used to detect and estimate coliform population of a water sample. This test is carried out by

Mechanisms of sex determination and dosage compensation, XYY humans are fer...

XYY humans are fertile males. XXX humans are fertile females. What do these observations reveal about the mechanisms of sex determination and dosage compensation?

What is ascaris, What is ascaris? What is the disease caused by this worm? ...

What is ascaris? What is the disease caused by this worm? Ascaris, or Ascaris lumbricoides, is an animal of the nematode phylum, i.e., a roundworm. Ascaris causes ascariasis, a

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd