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Explain what is Genetic Factors ?
It has been suggested that certain genetic defect(s) could be partly responsible for increased risk of CAD in Asian Indians. No specific genetic defect has yet been identified butan excess prevalence or activation of the so-called 'thrifty' or pig-out gene [B3 subunit of heteromeric G protein (GNB3)l may be responsible for the development of obesity and metabolic syndrome when coupled with absence ofregular exercise (gene-environment interaction) - ultimately leading to Cardiovascular diseases. Ethnicity is a strong surrogate for this gene-environment interaction and may underlie the propensity to develop obesity and CVD due to natural selection of the 'thrifty' gene. Genetic predisposition may also be related to the Lipoprotein a (Lp-a), an atherogenic lipid fraction whose level is geneticallyDetermined and is found to be higher in Indians.
Q. Medical Management of mitral regurgitation? Vasodilator therapy to reduce afterload may be beneficial in patients with chronic mitral regurgitation, but there is no evidence
Hexokinase, that catalyzes the first irreversible step of glycolysis, is inhibited by glucose 6-phosphate. Thus when PFK is inhibited and fructose 6-phosphate builds up an
When underlying coronary artery disease is the cause of heart failure in the coronary revascularization may both improve symptoms and prevent progression. Patients with angina and
Floral Induction The transformation of vegetative apex into a floral apex is a multifactor and multistep phenomenon. Despite researches on flowering carried out during the las
Planning the Nursing Care The goals of nursing care are: Identify the causative factor of megaloblastic anaemia. Administer appropriate vitamins depending on
Explain Adverse effects of Amprenavir The most common adverse effects have been nausea, vomiting (especially in combination with zidovudine), perioral paresthesias and rash (J
The axons of all the baroreceptors in the body were destroyed at 2 AM. All else is normal. Which of the following statements is true for the system at 2:10 AM when compared to th
Define Energy Requirement for Cancer Patients? It must be clear to you that cancer imposes increased energy demands because of the hyper-metabolic state of the disease process
Explain Xeno-transplantation Xeno-transplantation could enable individuals to survive and contribute their alleles to the gene pool who might not have already done so thus inc
What is genes Duplication ? Duplication of genes can happen when a portion of a chromosome breaks off and attaches itself to the end of its homologous chromosome, as seen below
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