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Explain Theory of enzyme action
L. Michaelis and k L. Menten developed a general theory of enzyme action and kinetics in 1913. According to this theory, we learnt that in an enzyme substrate reaction, the ezzyme (E) first combines with the substrate (S) with the formation of an enzyme-substrate (ES) complex, which subsequently breaks down into the product (P) and the enzyme (E) is recovered. Thus, tlie enzyme catalyzed reaction proceeds in the following two steps:
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Symptoms contain fever, weakness, rashes, with erythema and edema. Serum sickness depends on the immune difficult formed and the size of the complexes.
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