Use of Chlamydia in Pregnancy 

Doxycycline, other tetracyclines and the flour quinolones generally should not be used during pregnancy. Azithromycin appears to be safe in pregnant women; most Medical  Letter consultants consider it the treatment of choice. Amoxicillin (Amoxil, and others), an effective alternative, is also safe. Many patients, pregnant or not, cannot tolerate the GI effects of erythromycin, and erythromycin estolate is contraindicated in pregnancy. In general, treatment failure may be more common in pregnancy and repeat testing is recommended. Patients who fail treatment can usually be retreated with the same drug.