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Where would a predicted silent mutation have to be situated to actually result in a loss-of-function mutation (and potentially lead to the onset of disease)?
A. Intron-exon junction/splice site
B. Translational start site
C. Stop codon
D. Anywhere within the exonic sequences
Before you solve the problem organize your thoughts on paper in the following manner. A) What will my answer look like? What units will I be using? B) What do I need to know
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