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Explain the Systemic Metabolic Responses?
Many of the metabolic responses to infection are similar to those following injury. The key changes include:
Hyper metabolism: Oxygen consumption is elevated in the infected patient. It may be 50-60% higher than normal and is related to the severity of the infection (PaCO3 of < 32 mmHg-hypelventilation). In the pre-operative and post injury period, such a response often occurs secondary to severe pneumonia, abdominal infection or wound infection. Increased metabolism is related to fever -being 10-13% for every 1°C elevation in temperature. The metabolic rate returns to normal as the infection resolves.
MITOCHONDRIA It is the power house of the cell because they are the major centers of release of energy in the aerobic respiration. Mitochondria and chloroplast both are a
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