Explain the oxidative phase of the pentose phosphate pathway, Biology

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With the help of reaction briefly explain the oxidative phase of the pentose phosphate pathway.

The oxidative branch of the pathway generates NADPH and pentose-5 phosphate, through  the  following reactions:

i)  Glucose-6-phosphate  is dehydrogenated  to  6-phosphogluconate via  6- pliosphoglucaono-lactone  by glucosed-phosphate  dehydrogenase  in presence of NADP'  and the cofactors Mg++,  Mn++  or Ca++.

 


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