Explain the molecular basis for the rigor state, Chemistry

Assignment Help:

1.  The pH of a 0.02 M solution of an acid was measured as 4.6. 

            a) What is the [H+] of the solution?

            b) What is the acid dissociation constant K and the pK for this acid?

2.  What are the [H+] and the pH of 500 ml of 2.5 X 10-9M NaOH?

3.  How many grams of sodium succinate (FW = 10 g/mol) and disodium succinate (FW = 162 g/mol) must be added to 1 L of water to produce a solution with a solution with pH 6.0 and a total succinate solute concentration of 50 mM? (for succinic acid  pK1 = 4.21, pK2 = 5.64)

4.  A diploid organism with a 45,000-kb haploid genome contains 21% G residues.  Calculate the number of A, C, G, and T residues in the DNA of each cell in this organism.

5.  Determine the subunit composition of a protein from the following information:

            Molecular mass by gel filtration: 400 kD

            Molecular mass by SDS-PAGE: 100 kD

            Molecular mass by SDS-PAGE with 2-mercaptoethanol: 40 kD and 60 kD

6.  The crocodile, which can remain under water without breathing for up to 1 hr, drowns its air-breathing prey and then dines at its leisure.  An adaptation that aids the crocodile in doing so is that it can utilize virtually 100% of the O2 in its blood whereas humans, for example, can extract only about 65% of the oxygen in their blood.  Crocodile Hb does not bind BPG.  However, crocodile deoxyHb preferentially binds HCO3-.  How does this help the crocodile obtain his dinner?

7.  A peptide has the sequence

                        Glu-His-Trp-Ser-Gly-Leu-Arg-Pro-Gly

What is the charge on the peptide at pH 3, 8 and 11?

8.  The highly pathogenic anaerobic bacterium Clostridium perfringens is responsible for gas gangrene, a condition where animal tissue is destroyed.  This bacterium secretes an enzyme that efficiently catalyzes the hydrolysis of a specific peptide bond as show below:

            -X-Gly-Pro-Y- + H2O → -X-COO- + +H3N-Gly-Pro-Y-

where X and Y are any of the 20 common amino acids.

How does the secretion of this enzyme contribute to the invasiveness of this bacterium?  Why does this enzyme not affect the bacterium itself?

9.  When a higher vertebrate dies, its muscles stiffen as they are deprived of ATP, a state called rigor mortis.  Explain the molecular basis for the rigor state.


Related Discussions:- Explain the molecular basis for the rigor state

What is graph, Q. What is graph? A graph is a visual demonstrate of d...

Q. What is graph? A graph is a visual demonstrate of data. Demonstrating your data in graphs is able to reveal a pattern if one exists. You will encounter numerous different

What are co-ordination compounds and its applications?, The co-ordination c...

The co-ordination compounds are of great importance. These compounds constitute the minerals, plants and are also present in animals. These play important functions. For example, c

Thermal reactions , Indicate whether the following thermal reactions are al...

Indicate whether the following thermal reactions are allowed concerted reactions by the Woodward-Hoffmann criteria. Classify the reaction according to type. On the basis of

SEPERATION TECHNIQUES, DRAW A SET UP FOR THE FOLLOWING SEPERATION TECHNIQUE...

DRAW A SET UP FOR THE FOLLOWING SEPERATION TECHNIQUES; FILTRATION,SEPERATING FUNNEL EVAPORATION ,DECANTATIOON, DISTILLATION.

Carbon valency, how carbon tetra-valency lead to stability?

how carbon tetra-valency lead to stability?

The shape of s -orbital is, The shape of s -orbital is: (1) Pyramidal ...

The shape of s -orbital is: (1) Pyramidal (2) Spherical (3)Tetrahedral (4)Dumb-bell shaped Ans: Spherical

Oxygen, OXYGEN Oxygen is the second most electronegative substance after...

OXYGEN Oxygen is the second most electronegative substance after fluorine, and forms thermodynamically stable compounds with usually all elements. It rivals fluorine in the abil

Haloform reactions, what is the chemistry behind haloform reactions?

what is the chemistry behind haloform reactions?

Equilibrium constant, What is the effect of the various concentrations of a...

What is the effect of the various concentrations of aniline hydrochloride on the ph and the X value, and what''s the logic behind all this

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd