Explain the Metabolic activities of the kidney

For synthesis of creatine, three amino acids glycine, arginine and methionine are involved directly. The first reaction is to form glycocyamine from arginine and glycine. This occurs in the kidneys. Tbe synthesis is completed by methylation of glycocyamine in the liver. Creatinine is an anhydride of creatine. The kidney is also involved in carbohydrate metabolism. Glucose-6-phosphate is present in the renal cortex. This enables the kidney to contribute some glucose to the blood of glycogenolysis (the breaking down or catabolism of the polysaccharide glycogen into molecules of the sugar glucose and molecules of glucose - I -phosphate within the body by enzymes). Kidneys also contribute glucose to the blood by gluconeogenesis (the production of glucose from non-carbohydrate precursors, such as amino acids, within the liver).