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Explain the endochondral ossification
The second type of osteogenesis is endochondral ossification. This process is different from intramembranous ossification in that it occurs with a cartilage base. Endochondral ossification is responsible for a good deal of formation of the long bones , vertebrae and portion of the mandible. It occurs in the following steps: Embryonic mesenchymal stem cells differentiate into a primitive hyaline cartilage. Blood vessels and bone- forming units, which resorb the cartilage and replace it with osteoid, invade this matrix.
Describe the Physiology of atrial septal defect? In ASD the magnitude of left to right shunt is determined by the size of the defect and the relative compliance of the right ve
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