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Explain the endochondral ossification
The second type of osteogenesis is endochondral ossification. This process is different from intramembranous ossification in that it occurs with a cartilage base. Endochondral ossification is responsible for a good deal of formation of the long bones , vertebrae and portion of the mandible. It occurs in the following steps: Embryonic mesenchymal stem cells differentiate into a primitive hyaline cartilage. Blood vessels and bone- forming units, which resorb the cartilage and replace it with osteoid, invade this matrix.
Influence of Yolk on Cleavage Though biological significance of yolk is to provide nourishment to the developing embryo, it is not part of the active cytoplasm. Yolk is dead
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