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Explain the effect of Deficiency of pyridoxine?
A deficiency of vitamin B6 alone is uncommon because it usually occurs in association with a deficit in other B-complex vitamins. Early biochemical changes include decreased levels of plasma pyridoxal 5'-phosphate (PLP) and urinary 4-pyridoxic acid. These are followed by decrease in synthesis of transaminuses (aninotransferases) and other enzymes of amino acid metabolism such hat there is an increased presence of xanthurenate in the urine and a decreased glutamate conversion to the anti- neurotransmitter α-aminobutyrate. Hypovitaminosis B6 may often occur with riboflavin deficiency, because riboflavin is needed for the formation of the coenzyme PLP.
Infants are especially susceptible to insufficient intakes, which can lead to epileptic form convulsions. Skin changes include dermatitis with cheilosis and glossitis. Moreover, there is usually a decrease in circulating lymphocytes and sometimes a normochromic, microcytic, or sideroblastic anaemia as well. The sensitivity of such systems as sulphur amino acid metabolism to vitamin B6 availability is reflected in homocysteinaernia. A decrease in the metabolism of glutamate in the brain, which is found in vitamin B6 insufficiency, reflects a nervous system dysfunction. As is the case with other micronutrient deficiencies, vitamin B6 deficiency results in an impairment of the immune system. Of current concern is the pandemic-like occurrence of low vitamin B6 intakes in many people who eat poorly (e.g. people with eating disorders). Vitamin B6 deficiency has also been observed in south-east Asian school children (infected with hookworm), elderly Europeans (Dutch), and in some individuals with hyperhomocysteinaemia or who are on chronic haemodialysis. Several medical conditions can also affect vitamin B6 metabolism and thus lead to deficiency symptoms.
Q. Basis of Classification on Form-relationship principle? As pointed out earlier, this system is mainly based on Form-relationship principle. thus the various genera were. g
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Vegetative Development - Differentiation It is referred to as qualitative changes that lead to increased specialisation. For example, the formation of cells and tissues of roo
Angiographic Quantification Gr 1 - minimal systolic jet, clears rapidly Gr 2 - partial RA opacification Gr 3 - Opacification of whole of RA GR4 - Opacification of
Processing grains and oil seeds for animal feeding Simple processing of grains such as grinding facilitates the digestion particularly in cattle and buffaloes. Fine grinding of
Q. What is Pulmonary Veins in Normal Pulmonary Vasculature? The right and left upper lobe or superior pulmonary veins descend lateral to the arteries, cross in front of the hil
What conclusion you can draw about microorganisms that you saw under microscope from the plaque of your teeth?
peptide bond
Q. Explain Spoilage of Sweetened condensed milk? The sweetened condensed milk contains about 8% milk fat, 23% total milk solids and sweetened with the addition of a sweetener,
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