Explain the absorption, storage and elimination of thiamin, Biology

Assignment Help:

Explain the Absorption, Storage and Elimination of thiamin?

After a meal, thiamin is found in the intestine in the free form. Its absorption involves two mechanisms- both active and passive. At lower Intraluminal concentrations (of <1-2mmol/L) thiamin is absorbed by an active sodium-dependent carrier-mediated system. This mechanism involves phosphorylation. At a higher concentration, passive diffusion occurs thiamin is absorbed primarily from the upper jejunum by diffusion and by an active transport mechanism but can also occur in the duodenum and ileum.

After absorption, only a small part passes into circulation as free thiamin while a  greater part is converted into thiamin pyrophosphate (TBP) in the liver and intestinal  rnucosa with the help of the enzyme thiamin  kinase and AT?. A small quantity of thiamin is also converled into thiamin triphosphate (TTP). Thiamin is transported in blood by facilitated diffusion - in erythrocytes in both free and phosphorylated forms and in plasma as free thiamin and TMP. Thiamin or its phosphorylated derivatives are present in negligible amounts in various tissues. Thiamin is excreted in urine.


Related Discussions:- Explain the absorption, storage and elimination of thiamin

Create a dichotomous key for ant, Create a dichotomous key the following or...

Create a dichotomous key the following organisms, ant, butterfly, fly, beetle, grass hopper, wasp, ladybug, roach and dragonfly.

Complications of exchange transfusion, Complications of Exchange Transfusio...

Complications of Exchange Transfusion i) Infection of umbilical vessels and systemic injection related to blood transfusion like malaria, CMV, AIDS and hepatitis B. ii) O

Xerarch - ecology, Xerarch - Ecology Successions initiated on bare roc...

Xerarch - Ecology Successions initiated on bare rock, wind-blown sand, rocky talus slopes, or other situations where there is an extreme deficiency of water are termed xerarch

Illustrate meiosis ii and meiosis i, Q. How many cells are made after meios...

Q. How many cells are made after meiosis II and meiosis I? After meiosis II four cells are created, After Meiosis I two cells with already separated homologous are created

Chemical energy of matter, Chemical energy of matter : As is obvious from ...

Chemical energy of matter : As is obvious from  the above  account  living cells  obtain  energy  by breaking   C-C and C-H bonds  of organic  matter under the  process of catabol

State the medial pterygoid, Medial pterygoid Muscle bounds the pterygom...

Medial pterygoid Muscle bounds the pterygomandibular space medially which is entered when an inferior alveolar nerve block is administered. Infection of this space is dangerous

Amoeboid tapetum - tapetum, Amoeboid Tapetum - Tapetum It is also know...

Amoeboid Tapetum - Tapetum It is also known as invasive or periplus modial tapetum. This type of tapetum is more prevalent in the monocotyledons (Arum) than in the dicotyledon

Signs and symptoms of emphysema, Pathophysiology Distension and damage...

Pathophysiology Distension and damage of the respiratory bronchioles selectively occur. Opening develops in the walls of the bronchioles. and they become enlarged and conf

Flightless birds, #Most of the world''s flightless birds are either nocturn...

#Most of the world''s flightless birds are either nocturnal and secretive (e.g. the kagu) or large, swift and well-armed (the ostrich). The exceptions are found primarily on island

Adverse effects, Hypotension, hyperkalemia, taste disturbance, angiedema, r...

Hypotension, hyperkalemia, taste disturbance, angiedema, renal insufficiency. In the absence of any symptoms of hypotension, and normal renal function and K + levels, the dosage

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd