Explain the absorption, storage and elimination of thiamin, Biology

Assignment Help:

Explain the Absorption, Storage and Elimination of thiamin?

After a meal, thiamin is found in the intestine in the free form. Its absorption involves two mechanisms- both active and passive. At lower Intraluminal concentrations (of <1-2mmol/L) thiamin is absorbed by an active sodium-dependent carrier-mediated system. This mechanism involves phosphorylation. At a higher concentration, passive diffusion occurs thiamin is absorbed primarily from the upper jejunum by diffusion and by an active transport mechanism but can also occur in the duodenum and ileum.

After absorption, only a small part passes into circulation as free thiamin while a  greater part is converted into thiamin pyrophosphate (TBP) in the liver and intestinal  rnucosa with the help of the enzyme thiamin  kinase and AT?. A small quantity of thiamin is also converled into thiamin triphosphate (TTP). Thiamin is transported in blood by facilitated diffusion - in erythrocytes in both free and phosphorylated forms and in plasma as free thiamin and TMP. Thiamin or its phosphorylated derivatives are present in negligible amounts in various tissues. Thiamin is excreted in urine.


Related Discussions:- Explain the absorption, storage and elimination of thiamin

Phylogenetic species concept, Q. Phylogenetic species concept ? Taxonom...

Q. Phylogenetic species concept ? Taxonomists (scientists who compare, classify and name organisms) tend to describe a species by studying their physical characteristics and be

How yersinia enterolytica infection occurs, Normal 0 false fa...

Normal 0 false false false EN-IN X-NONE X-NONE MicrosoftInternetExplorer4 How Yersinia enterol

Glomerular filtrate, Normal 0 false false false EN-IN ...

Normal 0 false false false EN-IN X-NONE X-NONE MicrosoftInternetExplorer4

What is myocardial infarction, Q. What is myocardial infarction? The My...

Q. What is myocardial infarction? The Myocardial infarction is the condition in which an area of this tissue or the entire heart muscle dies by hypoxia due to lack of blood irr

Supenisory nursing round, Supenisory Nursing Round: Supervisory rounds...

Supenisory Nursing Round: Supervisory rounds are tours or excursions into areas where patients are cared for where personnel operate, where intra and inter departmental commun

Predominantly affects of gout disease, Q. Predominantly affects of gout dis...

Q. Predominantly affects of gout disease? The disease predominantly affects males after the age of 35 years. Gout starts suddenly with an arthritic pain in the big toe and may

Define foam spray drying method, Define Foam Spray Drying Method? This...

Define Foam Spray Drying Method? This is an extension of spray drying and involves the use of gases dissolved under pressure prior to spraying. The main advantage is that the

Observing where soil bacteria live, Observing where soil bacteria live ...

Observing where soil bacteria live Dig up a clover, alfalfa or soy-bean plant. Carefully increase all the soil from the roots and see if you can find the little white nodules o

What are sensory receptors, Q. What are sensory receptors? Sensory rece...

Q. What are sensory receptors? Sensory receptors are structures specialized in the acquiring of information, mechanical pressure, like temperature, pH, luminosity and chemical

Test, which area of the basal nuclei is responsible for controlling appendi...

which area of the basal nuclei is responsible for controlling appendicular muscle tone?

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd