Explain the absorption, storage and elimination of thiamin, Biology

Assignment Help:

Explain the Absorption, Storage and Elimination of thiamin?

After a meal, thiamin is found in the intestine in the free form. Its absorption involves two mechanisms- both active and passive. At lower Intraluminal concentrations (of <1-2mmol/L) thiamin is absorbed by an active sodium-dependent carrier-mediated system. This mechanism involves phosphorylation. At a higher concentration, passive diffusion occurs thiamin is absorbed primarily from the upper jejunum by diffusion and by an active transport mechanism but can also occur in the duodenum and ileum.

After absorption, only a small part passes into circulation as free thiamin while a  greater part is converted into thiamin pyrophosphate (TBP) in the liver and intestinal  rnucosa with the help of the enzyme thiamin  kinase and AT?. A small quantity of thiamin is also converled into thiamin triphosphate (TTP). Thiamin is transported in blood by facilitated diffusion - in erythrocytes in both free and phosphorylated forms and in plasma as free thiamin and TMP. Thiamin or its phosphorylated derivatives are present in negligible amounts in various tissues. Thiamin is excreted in urine.


Related Discussions:- Explain the absorption, storage and elimination of thiamin

Define physical activity as a factor for obesity, Define Physical activity ...

Define Physical activity as a factor for obesity? Sedentary life style with lack of an exercise schedule tends to make one obese. As we approach middle age, our physical activi

Show the process of healing abutment, Q. Show the process of Healing abutme...

Q. Show the process of Healing abutment? Healing abutments are therefore not considered ideal. It is for this reason that the definitive abutment, selected at first stage surge

Steps of initiation , The entire mechanism of protein synthesis i...

The entire mechanism of protein synthesis in eukaryotes is generally the same as in prokaryotes, with three phases explained as termination, elongation and initiation. Furthermore,

Pulsatile perfusion-type of blood pump, Pulsatile Perfusion: Conventional...

Pulsatile Perfusion: Conventional pumps give continuous flow with very little pulsatile property. Pulsatile perfusion is likely to result in better post operative renal and cardi

Describe the common operations performed in pcs, Describe the common operat...

Describe the common operations performed in paediatric cardiac surgery 1) Closed Heart Surgery: Surgery on Heart or Great Vessels done without using the Heart-Lung machine.

Particulate theory - pre-mendelian theory, Particulate Theory (i)      ...

Particulate Theory (i)         Maupertuis (1689-1759) proposed that the body of each parent give rise to minute particles. (ii)         In sexual reproduction, these particl

What are the corals, Q What are the corals? Corals are characterized by...

Q What are the corals? Corals are characterized by their polypoid shape, slow growth and sessility and secretion of a solid skeleton made of calcium carbonate. Numerous coral i

Define sugar as a type of carbohydrates, Define Sugar as a type of Carbohyd...

Define Sugar as a type of Carbohydrates? This group includes monosaccharide and disaccharides. List down the names of sugars under both these groups and check it out with those

Name the various test batteries, Name the various Test batteries Test ...

Name the various Test batteries Test batteries typically assess the following domains: General cognitive ability Language ability Visuoperceptual and constructi

Explain the treatment of travelers diarrhea, Treatment of travelers'diarrhe...

Treatment of travelers'diarrhea  The most common cause of travelers' diarrhea, usually a self-limited illness lasting several days, is infection with noninvasive enterotoxigeni

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd