Explain the absorption, storage and elimination of thiamin, Biology

Assignment Help:

Explain the Absorption, Storage and Elimination of thiamin?

After a meal, thiamin is found in the intestine in the free form. Its absorption involves two mechanisms- both active and passive. At lower Intraluminal concentrations (of <1-2mmol/L) thiamin is absorbed by an active sodium-dependent carrier-mediated system. This mechanism involves phosphorylation. At a higher concentration, passive diffusion occurs thiamin is absorbed primarily from the upper jejunum by diffusion and by an active transport mechanism but can also occur in the duodenum and ileum.

After absorption, only a small part passes into circulation as free thiamin while a  greater part is converted into thiamin pyrophosphate (TBP) in the liver and intestinal  rnucosa with the help of the enzyme thiamin  kinase and AT?. A small quantity of thiamin is also converled into thiamin triphosphate (TTP). Thiamin is transported in blood by facilitated diffusion - in erythrocytes in both free and phosphorylated forms and in plasma as free thiamin and TMP. Thiamin or its phosphorylated derivatives are present in negligible amounts in various tissues. Thiamin is excreted in urine.


Related Discussions:- Explain the absorption, storage and elimination of thiamin

Dopamine for working memory, Dopamine is important for working memory and d...

Dopamine is important for working memory and drug that increases the level of dopamine in the brain or facilities the action of dopamine, enhances working memory capabilities.Dopam

Define factorial method to calculate nitrogen requirements, Define Factoria...

Define Factorial method to Calculate Nitrogen Requirements? The nitrogen requirements have been calculated by a factorial method suggested by different expert groups, described

Basics of echocardiography, Echocardiography is one of the -most frequent...

Echocardiography is one of the -most frequently used imaging modalities for diagnosing cardiovascular diseases. It i's versatile and is applicable in the entire spectrum of

What is kingdom protista in diversity of life, What is Kingdom Protista in ...

What is Kingdom Protista in diversity of life? Members of Kingdom Protista are grouped separately from the other eukaryotic kingdoms because most of the organisms have a unicel

Phlum arthropoda, how to write a project on phylum arthropoda

how to write a project on phylum arthropoda

Vitamins, Which vitamin is useful for the clotting of blood?

Which vitamin is useful for the clotting of blood?

Advantage and disadvantages of fensom and spanner, Advantage and disadvanta...

Advantage and disadvantages of Fensom and Spanner Electroosmotic Flow Hypothesis The model has several advantages over Munch's model. The presence of P- proteins, and the occl

Key skills for healthy coping, Key skills for healthy coping are: - Pr...

Key skills for healthy coping are: - Problem-solving and goal setting skills: Finding a problem and challenges, thinking of alternatives for dealing with them, testing those

Byproducts high in energy and nitrogen, Byproducts high in energy and nitro...

Byproducts high in energy and nitrogen Byproducts in this category include products such as blood meal and poultry offal meal, fish meal, extracted oilseed meals/cakes and wast

What is gum arabic, Gum Arabic Gum Arabic or Gum Acacia is the oldest  ...

Gum Arabic Gum Arabic or Gum Acacia is the oldest  and best known of the natural gums. Gum Arabic is the natural exudate produced by various species of the thorny Acacia trees

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd