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Explain the Absorption, Storage and Elimination of Folate?
Folic acid is readily absorbed from the small intestines through the portal vein and passed onto the tissues through general circulation. Naturally occurring food folate is converted into the monoglutamate form by the enzyme pteroylpolyglutarnate hydrolase or folate conjugase or glutamate carboxypeptidase II, located in the jejunal brush border membrane. After de conjugation, the monoglutaniyl folate is transported across the membrane by a pH-dependent carrier-mediated mechanism.
Folic acid once absorbed is acted upon by hepatic dihydrofolate reductase to convert to its metabolically active form which is tetrahydrofolic acid (THF). Following absorption, folic acid is largely reduced and methylated in the liver to 'N-5 methyltetrahydrofolic acid, which is the main transporting and storage form of folate in the body. Folate transport across membranes into cells in kidney, placenta and choroid plexus, occurs via membrane-associated folate binding proteins that act s folate receptors and facilitate cellular uptake of folate. Larger doses of folate may escape metabolism by the liver and appear in the blood mainly as folic acid.
Describe a. the factors responsible for promoting lactation, and b. the mechanism responsible for the cessation of lactation when a mother weans her baby.
Mode of nutrition in lizards
Q. What benefits can commensalism offer to a species? The Commensalism may involve obtainment of food (for instance, the innocuous bacteria of the human gut), shelter or suppor
Enumerate about the diseases Insomnia The results from studies of people, who claim that they do not sleep, or wake up frequently from sleep show that their insomnia can have m
Choose one property of water and explain why that property is important to life.
can u show the different activities on the topic
what is bowman''s capsule?
life cycle of ascomycota
The cell cycle undergoes a sequence of changes which involve a period of growth replication of DNA, Followed by cell division. This sequence of changes is called cell cycle.
Explain the Properties of Gum tragacanth Gum tragacanth swells in water to give thick viscosity dispersions or pastes similar in texture to soft gels. The viscosity shows a sh
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