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Explain The absorption of itraconazole capsules
It is decreased with concurrent use of drugs that reduce gastric acidity, such as antacids, H2-receptor blockers, proton pump inhibitors or didanosine (Videx).
Itraconazole is a potent inhibitor of the hepatic isozyme CYP3A4 and may enhances serum concentrations of drugs that are metabolized by this enzyme. For this reason, itraconazole is contraindicated with the following drugs: cisapride (Propulsid), dofetilide (Tikosyn), ergot alka- loids, levomethadyl (Orlaam), lovastatin, oral midazolam (Versed, and others), pimozide (Orap), quinidine, simvastatin, and triazolam (Halcion, and others). Itraconazole is itself also a substrate of CYP3A4; its metabolism may be affected by both inducers of the enzyme, such as rifampin and carbamazepine (Tegretol, and others), and by other inhibitors.
Explain the Superficial Minor Burns? Superficial minor bums are immersed immediately in cool water if possible. The burn is carefully cleaned to prevent infection. If dirt is d
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Genomic clone is the piece of a DNA taken from genome of a cell or an animal, and spliced into the bacteriophage or other kind of cloning vector. A genomic clone might contain cod
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Which of the following E. coli can utilize lactose? Explain your answer. (-) superscript means mutation in the gene. Explain why the strain is able or unable to utilize la
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