Explain terbinafine, Biology

Assignment Help:

Explain Terbinafine

Terbinafine (Lamisil)  -  Terbinafine is a synthetic allylamine approved by the FDA for treatment of onychomycosis of the toenail or fingernail due to dermatophytes. It likely acts by inhibiting squalene epoxidase and blocking ergosterol synthesis. The most commonly reported adverse effects of oral terbinafine have been headache, gastrointestinal symptoms containing diarrhea, dyspepsia and abdominal pain, and occasionally a taste disturbance that may occur for weeks after the drug is stopped. Rash, pruritus and urticaria, usually mild and transient, have occurred. Toxic epidermal necrolysis and erythema multiforme have been reported. Increased aminotransferase activity and serious hepatic injury have occurred. Liver function should be assessed before initiation and occasionally during treatment with terbinafine. Anaphylaxis, pancytopenia and severe neutropenia have also been reported.

 


Related Discussions:- Explain terbinafine

Types of blastula, TYPES OF BLASTULA - Blastulas are of following type ...

TYPES OF BLASTULA - Blastulas are of following type -                    1 .       STEREOBLASTULA - The blastocoel is very small. It's blastomere are less in num

Contact guidance - modes of cell movement, Contact guidance - Modes of Cell...

Contact guidance - Modes of Cell Movement Besides chemical / ionic factors that regulate cell movement in developing embryos, physical factors as well appear to play a role in

What is orthopedic, Orthopedic Prophylactic antistaphylococcal drugs ad...

Orthopedic Prophylactic antistaphylococcal drugs administered preoperatively can decrease the incidence of both early and late infection following joint replacement. They also

Fertilization in earthworm, In earthworms, when the ovaries mature, the cli...

In earthworms, when the ovaries mature, the clitellum secretes a viscous substance in the form of a girdle. This girdle hardens in to a cocoon around the clitellum. The ova are dis

Precautions for determination of iodine number of lipids, Precautions for d...

Precautions for determination of iodine number of lipids? 1. If using the pipette for transferring the oil, allow the pipette to drain slowly and completely, as oil takes time

Explain dietary fibre - thyphoid, Dietary fibre Dietary fibre: Typhoid ...

Dietary fibre Dietary fibre: Typhoid patient has an inflamed intestinal mucosa, which can be easily perforated  and  ulcerated leading  to internal  haemorrhage. Thus foods hig

Define methods of estimation of ascorbic acid (vitamin c), Define Methods o...

Define Methods of Estimation of Ascorbic Acid (Vitamin C)? Ascorbic acid is also known as vitamin C which is a water soluble vitamin. As you already know, vitamins are a group

Explain the bohr''s model, Explain the Bohr's model? Bohr's Model :  ...

Explain the Bohr's model? Bohr's Model :  Electrons move around the nucleus at tremendous speeds and occupy most of the space in an atom. The exact position or location of an

What is right patellar tendon, What is right patellar tendon Which of t...

What is right patellar tendon Which of the following occur in response to an increase in the length of the right knee extensors in response to a quick tap applied to the right

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd