Explain terbinafine, Biology

Assignment Help:

Explain Terbinafine

Terbinafine (Lamisil)  -  Terbinafine is a synthetic allylamine approved by the FDA for treatment of onychomycosis of the toenail or fingernail due to dermatophytes. It likely acts by inhibiting squalene epoxidase and blocking ergosterol synthesis. The most commonly reported adverse effects of oral terbinafine have been headache, gastrointestinal symptoms containing diarrhea, dyspepsia and abdominal pain, and occasionally a taste disturbance that may occur for weeks after the drug is stopped. Rash, pruritus and urticaria, usually mild and transient, have occurred. Toxic epidermal necrolysis and erythema multiforme have been reported. Increased aminotransferase activity and serious hepatic injury have occurred. Liver function should be assessed before initiation and occasionally during treatment with terbinafine. Anaphylaxis, pancytopenia and severe neutropenia have also been reported.

 


Related Discussions:- Explain terbinafine

Zoonoses disease-chikungunya, Chikungunya Chikungunya, a metazoonosis,...

Chikungunya Chikungunya, a metazoonosis, is caused by chikungunya virus belonging to genus Alphavirus of the family Togavirideae. The virus is transmitted by infected mosquito

Necrotic enteritis, N e c r otic enteritis It can be designated as ...

N e c r otic enteritis It can be designated as enterotoxaemia of chickens, turkeys and ducks caused by Clostridium perfringens. The toxin released by this spore-bearing a

Explain the types of photoelectric cells, Question 1. State the basic p...

Question 1. State the basic properties of light. Discuss the special features of ultra-microscopy and phase contrast microscopy 2. What are ultrasonic waves? Explain the dif

General procedure of titration - nutritional biochemistry, Define General ...

Define General procedure of titration - Nutritional  Biochemistry? In general a titration requires that we add precise amounts of the known titrant to the unknown analyte or ti

Physical concepts of plant water relation - osmosis, Physical Concepts of P...

Physical Concepts of Plant Water Relation - Osmosis Osmosis is a special case of diffusion. Here, the movement of water (solvent) takes place from a region of higher c

On average what is the life duration of the red blood cells, On average wha...

On average what is the life duration of the red blood cells? Where are they destroyed? What is the destination of the heme groups after the destruction of hemoglobin molecules?

When manifested in homozygosity in the offspring?, Why can it be said that ...

Why can it be said that a recessive allele can remain hidden in the phenotype of an individual and revealed only when manifested in homozygosity in the offspring? A recessive a

Why does bark often break and die naturally, Why does bark often break and ...

Why does bark often break and die naturally? Bark is the mature periderm of the branches, stem and roots. It breaks and dies when these structures grow and thus the peridermal

Explain cori cycle , Under the limiting oxygen conditions experienced in ...

Under the limiting oxygen conditions experienced in by vigorous exercise, the configuration of NADH by glycolysis exceeds the ability of the respiratory chain to oxidize it back to

Spermatogenesis, SPERM A T OGENESIS The process of maturation of ...

SPERM A T OGENESIS The process of maturation of reproductive cells in the testes of male to form spermatozoa (sperm) is known as spermatogenesis. The testes are formed

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd