Explain terbinafine, Biology

Assignment Help:

Explain Terbinafine

Terbinafine (Lamisil)  -  Terbinafine is a synthetic allylamine approved by the FDA for treatment of onychomycosis of the toenail or fingernail due to dermatophytes. It likely acts by inhibiting squalene epoxidase and blocking ergosterol synthesis. The most commonly reported adverse effects of oral terbinafine have been headache, gastrointestinal symptoms containing diarrhea, dyspepsia and abdominal pain, and occasionally a taste disturbance that may occur for weeks after the drug is stopped. Rash, pruritus and urticaria, usually mild and transient, have occurred. Toxic epidermal necrolysis and erythema multiforme have been reported. Increased aminotransferase activity and serious hepatic injury have occurred. Liver function should be assessed before initiation and occasionally during treatment with terbinafine. Anaphylaxis, pancytopenia and severe neutropenia have also been reported.

 


Related Discussions:- Explain terbinafine

What is a membrane, Membrane is any delicate sheet that divides one region ...

Membrane is any delicate sheet that divides one region from other blocking or permitting (selectively or completely) the passage of substances. The skin, for example, can be consid

What are the two big groups into which cells are classified, What are the t...

What are the two big groups into which cells are classified? Cells can be divided as eukaryotic or prokaryotic. Prokaryotic cell is the cell that without a delimited nucleus

Calculate the volume of a 25% urethane solution, Assume that the blood volu...

Assume that the blood volume of a rabbit is 0.5 liters. If the effective dose of the anesthetic urethane is 10 micrograms/mL, calculate the volume of a 25% urethane solution that m

Regulation of testicular, Normal 0 false false false EN...

Normal 0 false false false EN-IN X-NONE X-NONE MicrosoftInternetExplorer4

Fats , FATS ( = True Fats, Triglycerides, Neutral Fats) They are es...

FATS ( = True Fats, Triglycerides, Neutral Fats) They are esters of fatty acids and 3-carbon trihydric alcohol glycerol (= glycerine). T rue fat is also called trig

What are the parathyroids, Q. What are the parathyroids? Where are they loc...

Q. What are the parathyroids? Where are they located and what are the hormones secreted by these glands? The parathyroids are four small glands embedded two in each posterior f

Explain risk factor global perspective in heart dieases, Explain risk facto...

Explain risk factor at the global perspective in heart diease? While the risk of Cardio-vascular diseases has been found to be variable in different ethnic groups with the high

Is neuron b in the frog central nervous system, IS Neuron B in the frog cen...

IS Neuron B in the frog central nervous system Consider Neuron B in the frog central nervous system whose plasma membrane has a previously unknown channel that is selectly cond

Nature of viral diseases, N a ture of viral diseases Viral diseases ...

N a ture of viral diseases Viral diseases are manifested in acute, sub-acute or chronic forms, as frank clinical cases or as latent infections, some of which are fatal. Thes

Explain cigrates smoking from lifestyle risk factors, Explain cigrates smok...

Explain cigrates smoking from lifestyle risk factors ? Smoking is the single most important preventable risk factor for CAD. There is strong evidence that smoking can significa

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd