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Explain Terbinafine
Terbinafine (Lamisil) - Terbinafine is a synthetic allylamine approved by the FDA for treatment of onychomycosis of the toenail or fingernail due to dermatophytes. It likely acts by inhibiting squalene epoxidase and blocking ergosterol synthesis. The most commonly reported adverse effects of oral terbinafine have been headache, gastrointestinal symptoms containing diarrhea, dyspepsia and abdominal pain, and occasionally a taste disturbance that may occur for weeks after the drug is stopped. Rash, pruritus and urticaria, usually mild and transient, have occurred. Toxic epidermal necrolysis and erythema multiforme have been reported. Increased aminotransferase activity and serious hepatic injury have occurred. Liver function should be assessed before initiation and occasionally during treatment with terbinafine. Anaphylaxis, pancytopenia and severe neutropenia have also been reported.
Explain Unresorbable Barriers - Root Perforation MTA exhabits excellent tissue biocompatible non resorbable barrier and restorative material. It represents an extraord
Mammalian Lungs - Respiration In this we will study mainly mammalian lungs as it is the best representative of a respiratory surface adapted for terrestrial respiration. For t
Define Polyacrylamide gel electrophoresis (PAGE)? Acrylamide gel has the advantage over starch in that it is easier to prepare and is more inert, the pore size can be varied in
Water Loss - Plant Water Relation Plants lose about 98% of water to the atmosphere by transpiration. Often water loss by transpiration exceeds gain by absorption and results
What are the similarities between chlorplasts and prokaryotic cells?
Define the Elimination of Vitamin E? The primary oxidation product of α-tocopherol is α-tocophery quinone that can be conjugated to yield the glucuronate. This glucnronide is e
How does the absence of a nuclear envelope in prokaryotes prevent prokaryotes from controlling gene expression by modifying RNA after transcription? Without a nuclear envelope
Starting at the esophagus, trace the pathway of food through the system. At each organ, indicate anatomical adaptations to the general GI tract tube structure that enhance the spec
Mentalis The mental tubercles on either side of mental protruberance(in midline) gives origin to the mentalis muscle. Above the mentalis origin, the incisivus muscle takes orig
Isoniazid Serum aminotransferase activity increases in 10% to 20% of patients taking isoniazid, especially in the early weeks of treatment, but often returns to normal even wh
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