Explain terbinafine, Biology

Assignment Help:

Explain Terbinafine

Terbinafine (Lamisil)  -  Terbinafine is a synthetic allylamine approved by the FDA for treatment of onychomycosis of the toenail or fingernail due to dermatophytes. It likely acts by inhibiting squalene epoxidase and blocking ergosterol synthesis. The most commonly reported adverse effects of oral terbinafine have been headache, gastrointestinal symptoms containing diarrhea, dyspepsia and abdominal pain, and occasionally a taste disturbance that may occur for weeks after the drug is stopped. Rash, pruritus and urticaria, usually mild and transient, have occurred. Toxic epidermal necrolysis and erythema multiforme have been reported. Increased aminotransferase activity and serious hepatic injury have occurred. Liver function should be assessed before initiation and occasionally during treatment with terbinafine. Anaphylaxis, pancytopenia and severe neutropenia have also been reported.

 


Related Discussions:- Explain terbinafine

Central carbons participate in the peptide bond, Q. Do the -H groups bound ...

Q. Do the -H groups bound to the central carbons participate in the peptide bond? The central carbons themselves, the -R groups and the hydrogen attached to the central carbons

Modern biology, Modern Biology Increasing advancement in biotechnology ...

Modern Biology Increasing advancement in biotechnology has brought about a veritable explosion of Biological knowledge since early 1950s.This vast modern biological information

Explain about mental foramen and nerve, Explain about Mental foramen and ne...

Explain about Mental foramen and nerve Mental foramen is a strategically important landmark during osteotomy procedures. Its location and the possibility that an anterior loop

Defina about the lipid metabolism, Defina about the Lipid Metabolism? A...

Defina about the Lipid Metabolism? Animal studies consistently show a hypotriglyceridenlic effect although equivocal results have been seen with healthy humans. Hypotriglycerid

What is impaired glucose tolerance, Q. What is Impaired Glucose Tolerance? ...

Q. What is Impaired Glucose Tolerance? Glucose tolerance is assessed by taking the fasting blood sugar value. An oral glucose load of 75 grams glucose is administered and blood

Define colorimetric method - 2, Define Colorimetric Method - 2, 4 Dinitroph...

Define Colorimetric Method - 2, 4 Dinitrophenylhydrazine Method? We shall use this method in estimating vitamin C in a given sample in the laboratory. Here, let us look at the

Difference between ectoparasite and endoparasite, Q. What is the difference...

Q. What is the difference between ectoparasite and endoparasite? The Ectoparasites are parasites that explore the external surface of the host (like, for instance, mites that p

Explain the classification of carbohydrates, Define Classification of Carbo...

Define Classification of Carbohydrates? Carbohydrates are defined as polyhydroxy aldehydes or ketones or substances that produce such compounds when hydrolyzed. Carbohydrates a

Barker’s in utero hypothesis, Barker’s in Utero Hypothesis The develop...

Barker’s in Utero Hypothesis The developmental origins of adult disease, often called as the ‘Barker hypothesis’ states that adverse influences early in development, particula

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd