Explain terbinafine, Biology

Assignment Help:

Explain Terbinafine

Terbinafine (Lamisil)  -  Terbinafine is a synthetic allylamine approved by the FDA for treatment of onychomycosis of the toenail or fingernail due to dermatophytes. It likely acts by inhibiting squalene epoxidase and blocking ergosterol synthesis. The most commonly reported adverse effects of oral terbinafine have been headache, gastrointestinal symptoms containing diarrhea, dyspepsia and abdominal pain, and occasionally a taste disturbance that may occur for weeks after the drug is stopped. Rash, pruritus and urticaria, usually mild and transient, have occurred. Toxic epidermal necrolysis and erythema multiforme have been reported. Increased aminotransferase activity and serious hepatic injury have occurred. Liver function should be assessed before initiation and occasionally during treatment with terbinafine. Anaphylaxis, pancytopenia and severe neutropenia have also been reported.

 


Related Discussions:- Explain terbinafine

What are venous vessels and veins, What are venous vessels, veins and venul...

What are venous vessels, veins and venules? Venous vessels are each blood vessel that carries blood from the tissues to the heart. Veins and venules are venous vessels. Venules

How proteins can be classified, How Proteins can be Classified? I. Shap...

How Proteins can be Classified? I. Shape and size: fibrous proteins and globular proteins. Fibrous proteins play structural roles  in organisms. Globular proteins consist of lo

Physical concepts of plant water relation - osmosis, Physical Concepts of P...

Physical Concepts of Plant Water Relation - Osmosis Osmosis is a special case of diffusion. Here, the movement of water (solvent) takes place from a region of higher c

Concerning their permeability how are membranes classified, Q. Concerning t...

Q. Concerning their permeability how are membranes classified? Membranes can be classified as permeable, impermeable, selectively permeable or semipermeable. An impermeable

Determine energy expenditure for climbers, Determine energy expenditure for...

Determine energy expenditure for Climbers? The energy expenditure of 3250 Kcal/ day is reported in climbers to Mt. Everest using doubly labeled water teaching. Out of this, 161

Define criteria for assessment of vitamin d status, Define Criteria for Ass...

Define Criteria for Assessment of Vitamin D Status? You may recall the events involved in calcium homeostasis described earlier in this section. We studied that sufficient 25-O

Explain haemophilus influenzae, Haemophilus influenzae type b (Hib) Hi...

Haemophilus influenzae type b (Hib) Hib is endemic worldwide. Previously unvaccinated infants

Why the pancreas is considered a mixed gland, Q. What is a mixed gland? Why...

Q. What is a mixed gland? Why the pancreas is considered a mixed gland? Mixed gland is a gland that produces exocrine and endocrine secretions. The pancreas is an example of

Direction of flow, Direction of flow--either towards or away from the trans...

Direction of flow--either towards or away from the transducer (positive or negative Doppler shifts). Timing-instantaneous velocity and direction of flow throughout the various

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd