Explain terbinafine, Biology

Assignment Help:

Explain Terbinafine

Terbinafine (Lamisil)  -  Terbinafine is a synthetic allylamine approved by the FDA for treatment of onychomycosis of the toenail or fingernail due to dermatophytes. It likely acts by inhibiting squalene epoxidase and blocking ergosterol synthesis. The most commonly reported adverse effects of oral terbinafine have been headache, gastrointestinal symptoms containing diarrhea, dyspepsia and abdominal pain, and occasionally a taste disturbance that may occur for weeks after the drug is stopped. Rash, pruritus and urticaria, usually mild and transient, have occurred. Toxic epidermal necrolysis and erythema multiforme have been reported. Increased aminotransferase activity and serious hepatic injury have occurred. Liver function should be assessed before initiation and occasionally during treatment with terbinafine. Anaphylaxis, pancytopenia and severe neutropenia have also been reported.

 


Related Discussions:- Explain terbinafine

Explain zanamivir, Zanamivir  (Relenza) Started within 2 days after on...

Zanamivir  (Relenza) Started within 2 days after onset of symptoms, this orally inhaled neuraminidase inhibitor can shorten the duration of illness and may decrease the incide

What would be the probability of obtaining result, A plant grown from one o...

A plant grown from one of Mendel's yellow peas is selfed. Five progeny peas are obtained from this self and they are all yellow. If the original selfed plant had been homozygous, w

What is the need of monitoring and surveillance, What is the need of Monito...

What is the need of Monitoring and Surveillance? Monitoring, we know, is the act of observing something and sometimes keeping a .record of it while surveillance is a repeated s

Heredity and variations, HEREDITY 1.         Like begets like i.e; ever...

HEREDITY 1.         Like begets like i.e; every living organism reproduces its own kind. Frog reproduce frogs, rats reproduce rats only. 2.         Heredity includes the cha

History of ecology, History of Ecology The roots of ecology lie in Natu...

History of Ecology The roots of ecology lie in Natural History, which is as old as human civilisation itself. As a matter of fact man indulged in ecology in a practical sort of

Bones, which bone forms the non-moving muscle attachment in the hip joint

which bone forms the non-moving muscle attachment in the hip joint

Pituitary disorders, PITUITARY DISORDERS - (a) Pituitary Dwarfism . It...

PITUITARY DISORDERS - (a) Pituitary Dwarfism . It is caused by the deficiency of growth hormones (GH) from childhood. It is characterised by small but well porportioned body a

Knock-out experiment, Knock-out experiment  is a method for deleting, mutat...

Knock-out experiment  is a method for deleting, mutating or otherwise inactivating the gene in a mouse. This laborious technique involves transfecting a crippled gene into cultured

Assessment of exstrophy of the bladder, Assessment You can observe it...

Assessment You can observe it visually at birth. The anterior abdominal wall is absent and the posterior bladder lining which is bright red in colour is exposed. Urine seeps

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd