Explain terbinafine, Biology

Assignment Help:

Explain Terbinafine

Terbinafine (Lamisil)  -  Terbinafine is a synthetic allylamine approved by the FDA for treatment of onychomycosis of the toenail or fingernail due to dermatophytes. It likely acts by inhibiting squalene epoxidase and blocking ergosterol synthesis. The most commonly reported adverse effects of oral terbinafine have been headache, gastrointestinal symptoms containing diarrhea, dyspepsia and abdominal pain, and occasionally a taste disturbance that may occur for weeks after the drug is stopped. Rash, pruritus and urticaria, usually mild and transient, have occurred. Toxic epidermal necrolysis and erythema multiforme have been reported. Increased aminotransferase activity and serious hepatic injury have occurred. Liver function should be assessed before initiation and occasionally during treatment with terbinafine. Anaphylaxis, pancytopenia and severe neutropenia have also been reported.

 


Related Discussions:- Explain terbinafine

Illustrate enzyme-substrate interaction, On what structural level of the en...

On what structural level of the enzyme (primary, secondary, tertiary or quaternary) does the enzyme-substrate interaction depend? The substrate binds to the enzyme in the activ

Explain the protein efficiency ratio (per), Explain the Protein Efficiency ...

Explain the Protein Efficiency Ratio (PER)? PER method was developed by Osborne, Mendel and Ferry in 1919 and is based on the growth of young rats. The diets usually contain 10

What events occur during platelet plug formation, What is the role of plate...

What is the role of platelet plug formation in hemostasis? What events occur during platelet plug formation? Describe the circumstances that may induce inappropriate platelet plug

Adhesion of cells to extracellular cell matrix, Adhesion of Cells to Extrac...

Adhesion of Cells to Extracellular Cell Matrix You know that the cells in order to move or change shape, adhere to each other or to the substratum in their environment. Usual

Neuroglia - organisation of nervous system, Neuroglia - Organisation of Ner...

Neuroglia - Organisation of Nervous System We may refer neuroglia as the connective tissue of the nervous system. It involves all elements of the nervous system other than ne

Eye - conjuctiva, CONJUNCTI V A - Ectodermal in origin. Formed by epi...

CONJUNCTI V A - Ectodermal in origin. Formed by epidermis. It is thin, transparent covers cornea. Made up of stratified epithelium. It has 2 parts - (i) Ocular conjunct

What is the meaning of body composition, What is the meaning of Body compos...

What is the meaning of Body composition? It refers primarily to the distribution of muscle, fat, bone and other tissues in the body, and its measurement is often considered as

Explain glycogenolysis, Glycogenolysis Unlike glycogenesis, glycogenoly...

Glycogenolysis Unlike glycogenesis, glycogenolysis is the  breakdown of glycogen. Glycogen is  broken down  in  the  liver and muscle catalysed  by  the  enzyme glycogen phosph

Fast response - biological responses, Fast Response - Biological Responses ...

Fast Response - Biological Responses Some of the fast responses are discussed below: It was found that when mung bean root tips were kept in a specific solution (contain

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd