Explain terbinafine, Biology

Assignment Help:

Explain Terbinafine

Terbinafine (Lamisil)  -  Terbinafine is a synthetic allylamine approved by the FDA for treatment of onychomycosis of the toenail or fingernail due to dermatophytes. It likely acts by inhibiting squalene epoxidase and blocking ergosterol synthesis. The most commonly reported adverse effects of oral terbinafine have been headache, gastrointestinal symptoms containing diarrhea, dyspepsia and abdominal pain, and occasionally a taste disturbance that may occur for weeks after the drug is stopped. Rash, pruritus and urticaria, usually mild and transient, have occurred. Toxic epidermal necrolysis and erythema multiforme have been reported. Increased aminotransferase activity and serious hepatic injury have occurred. Liver function should be assessed before initiation and occasionally during treatment with terbinafine. Anaphylaxis, pancytopenia and severe neutropenia have also been reported.

 


Related Discussions:- Explain terbinafine

Composed of proteins and dna, Chromosomes, colored bodies, are composed of ...

Chromosomes, colored bodies, are composed of proteins and DNA; so are chromatids. At metaphase I there are 46 chromosomesaligned in pairs along the human cells equatorial plate. At

Energy requirement during congestive cardiac failure, Q. Energy requirement...

Q. Energy requirement during congestive cardiac failure? Energy: Composition of the calorie requirements on the basis of body weight is usually not feasible due to the presence

Which are the extra abundant ribosomes in secretory cells, Q Which are the ...

Q Which are the extra abundant ribosomes in secretory cells - the free cytoplasmic ribosomes or those associated with the rough endoplasmic reticulum? Free cytoplasmic ribosome

What are gene interactions?, What are gene interactions? What are the three...

What are gene interactions? What are the three main types of gene interactions? The Gene interaction is the phenomenon in which a given phenotypical trait is conditioned by two

Explain the atp-sensitive potassium channel, ATP-sensitive potassium channe...

ATP-sensitive potassium channel?   A.  In smooth muscle cells surrounding an arteriole serving a region of the body that has just recently had very high levels of cellular acti

Factors affecting the rapeutic relationship, FACTORS AFFECTING THE RAPEUTIC...

FACTORS AFFECTING THE RAPEUTIC RELATIONSHIP: A  rapport  is developed between the nurse and  the patient. Rapport  is defined as, a relationship of mutual sympathy and underst

What is respiration quotient, a) Where casparian strips situated in a plant...

a) Where casparian strips situated in a plant body are and what are they made up of? Mention its function. b) What is respiration quotient (RQ)? Under what conditions will th

Acid-base imbalances from appearing in the body, List and briefly describe ...

List and briefly describe the mechanisms that prevent acid-base imbalances from appearing in the body. In addition, indicate where each mechanism functions most significantly.

Agarose gel electrophoresis, Agarose gel electrophoresis  is the method to ...

Agarose gel electrophoresis  is the method to analyze the size of the DNA (or RNA) fragments. In the presence of an electric field, bigger fragments of DNA move through a gel slowe

How is the circulatory system of birds characterized, How is the circulator...

How is the circulatory system of birds characterized? Birds, as every vertebrate, have a closed circulatory system. The heart is same to the mammalian heart, having four chambe

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd