Explain terbinafine, Biology

Assignment Help:

Explain Terbinafine

Terbinafine (Lamisil)  -  Terbinafine is a synthetic allylamine approved by the FDA for treatment of onychomycosis of the toenail or fingernail due to dermatophytes. It likely acts by inhibiting squalene epoxidase and blocking ergosterol synthesis. The most commonly reported adverse effects of oral terbinafine have been headache, gastrointestinal symptoms containing diarrhea, dyspepsia and abdominal pain, and occasionally a taste disturbance that may occur for weeks after the drug is stopped. Rash, pruritus and urticaria, usually mild and transient, have occurred. Toxic epidermal necrolysis and erythema multiforme have been reported. Increased aminotransferase activity and serious hepatic injury have occurred. Liver function should be assessed before initiation and occasionally during treatment with terbinafine. Anaphylaxis, pancytopenia and severe neutropenia have also been reported.

 


Related Discussions:- Explain terbinafine

Illustrate adaptation to terrestrial life, Q. Why can the allantois be cons...

Q. Why can the allantois be considered an adaptation to terrestrial life? The allantois is an adaptation to dry land because in embryos of oviparous terrestrial beings like bir

Nutrition, difference between holophytic nutrition and holozoic nutrition.

difference between holophytic nutrition and holozoic nutrition.

Explain the mode of feeding or nutrition support, Explain the Mode of Feedi...

Explain the Mode of Feeding or Nutrition Support? Do you recall studying about the nutrition support methods, namely enteral and perenteral feeding? These two methods form the

Endodontic success, Endodontic success - According to Strindberg 1956 ...

Endodontic success - According to Strindberg 1956 the endodontic success is the postoperative clinical as well as radiographic satisfaction after a predetermined postoperative

Zoonoses disease-monkey b virus disease, Monkey B virus disease The di...

Monkey B virus disease The disease is caused by Herpesvirus simiae or B virus, a member of the herpes group of viruses. The infection occurs naturally among primates of the ge

What is st heart rate index, Q. What is ST Heart Rate Index? To calcula...

Q. What is ST Heart Rate Index? To calculate the index, the maximum ST depression is divided by the Delta heart rate (difference between the resting and maximum heart rate). As

Principles governing cleavage, Principles Governing Cleavage a) The n...

Principles Governing Cleavage a) The nucleus and mitotic achromatic figure tend to occupy the centre of active cytoplasmic density of the dividing cells, e.g., in isolecithal

Which compounds does not contain an amine, Which of the following compounds...

Which of the following compounds does NOT contain an amine? Select one: a. Glutamine b. Acetate ion c. Urea d. Guanidinium ion e. Creatine

Dna replication, DNA Replication Deoxyribonucleic acid (DNA) is the car...

DNA Replication Deoxyribonucleic acid (DNA) is the carrier of genetic data for all living creatures. An organism's genome, made of DNA, encodes the genetic blueprint for buildi

Change in structure of a protein, Q. Is it expected that a change in the pr...

Q. Is it expected that a change in the primary, in the secondary or in the tertiary structure of a protein will produce furthermore functional consequences? Any change of the p

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd