Explain tenofovir disoproxil fumarate, Biology

Assignment Help:

Tenofovir disoproxil fumarate (TDF, Viread) 

Tenofovir DF is the only nucleotide RTI available for treatment of HIV. It is a prodrug of tenofovir, a potent inhibitor of HIV replication. Tenofovir DF is given once daily and is generally well tolerated. It is effective as part of initial HIV therapy and has activity against some HIV strains that are resistant to other NRTIs. It is available alone or in combination with emtricitabine (Truvada). Tenofovir should not be used in three-drug combinations  with abacavir/lamivudine or didanosine/lamivudine because of high  rates of virologic failure. Tenofovir is also active against HBV, even strains that are resistant to lamivudine.

 


Related Discussions:- Explain tenofovir disoproxil fumarate

Determine the occurrence of folic acid, Occurrence of folic acid Folic...

Occurrence of folic acid Folic acid is an active principle widely  occurring in the animal and vegetable kingdom. Richest sources are liver, dark  green leafy vegetables, bean

Discuss in brief distant and contact osteogenesis, Q. Discuss in brief dist...

Q. Discuss in brief distant and contact osteogenesis? Three terms are used to describe individual aspects of bone formation process that occur at implants. They are Osteocondu

How does a population differ from a community, How does a population differ...

How does a population differ from a community? A population having of all members of a single species that live in an area, while a community consists of all organisms of any s

Prodigality of nature, By prodigality of nature it is meant that organisms ...

By prodigality of nature it is meant that organisms have an enormous potential to reproduce. A carp or salmon is known to lay over a million eggs. A frog may lay Bs many as 12,000

Centrifugal pump-type of blood pump, Centrifugal Pump: This is available ...

Centrifugal Pump: This is available for clinical perfusion from 1976 (Bio Medicus Pump). It is disposable, causes less blood trauma and reduces the risk of massive air embolism.

Kidneys participate in the acid-basic equilibrium, Q. How do kidneys partic...

Q. How do kidneys participate in the regulation of the acid-basic equilibrium of the body? How are alkalosis and acidosis respectively corrected by the kidneys? Kidneys can reg

Osmoregulation in non-chordate metazoans, Osmoregulation in Non-Chordate Me...

Osmoregulation in Non-Chordate Metazoans Previously you have studied that in protozoans, particularly fresh water protozoans; contractile vacuoles play a significant role in t

Rh-factor, Rh-factor It is one of the factor associated with blood. ...

Rh-factor It is one of the factor associated with blood. In addition to ‘A', ‘B', ‘AB' and ‘O' groups, Rh factor test is also done in the blood. People having Rh factor a

Swine fever, S w i n e fever It is also known as hog cholera and re...

S w i n e fever It is also known as hog cholera and results in high fever and prostration. E t iology : Pestivirus belonging to family Togaviridae is responsi

Historical review of developmental biology, HISTORICA L REVIEW Anox...

HISTORICA L REVIEW Anoximander (600 B.C.) was the first western philospher who proposed the idea that "living creatures arose from the moist element". Empedocles (500 B.

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd