Explain tenofovir disoproxil fumarate, Biology

Assignment Help:

Tenofovir disoproxil fumarate (TDF, Viread) 

Tenofovir DF is the only nucleotide RTI available for treatment of HIV. It is a prodrug of tenofovir, a potent inhibitor of HIV replication. Tenofovir DF is given once daily and is generally well tolerated. It is effective as part of initial HIV therapy and has activity against some HIV strains that are resistant to other NRTIs. It is available alone or in combination with emtricitabine (Truvada). Tenofovir should not be used in three-drug combinations  with abacavir/lamivudine or didanosine/lamivudine because of high  rates of virologic failure. Tenofovir is also active against HBV, even strains that are resistant to lamivudine.

 


Related Discussions:- Explain tenofovir disoproxil fumarate

Explain divisions of the angiosperms, Q. What are the two divisions of the ...

Q. What are the two divisions of the angiosperms? The angiosperms are divided into dicotyledonous and monocotyledonous.

Respiratory system - developmental changes, Respiratory System - Developmen...

Respiratory System - Developmental Changes after Birth The new-born's lungs are collapsed and need powerful breaths to inflate them; airways too are small, offering remarkable

What is facultative anaerobic beings, What is the difference between facult...

What is the difference between facultative anaerobic beings and obligate anaerobic beings? Facultative anaerobic beings, such as the fungi Saccharomyces cerevisiae, a brewing y

What is an oligopeptide, Q. What is an oligopeptide? How is it differing fr...

Q. What is an oligopeptide? How is it differing from a polypeptide? Peptide is the molecule formed by the union of amino acids through the peptide bond. Oligopeptide is a pepti

Pressure flow mechanism for translocation, experiments that support pressur...

experiments that support pressure flow as a mechanism for translocation

Glucose-6-phosphate, Three molecules of ducose-6-phosphate  yield 3 molecul...

Three molecules of ducose-6-phosphate  yield 3 molecules of CO,  and 3 molecules of five carbon residues (pentose sugar). The latter are converted ultimately to  2 molecules  of  g

Explain rifampin, Options with Rifampin Standard 4-drug treatment regi...

Options with Rifampin Standard 4-drug treatment regimens including rifampin can be given to HIV-infected patients with active TB who are simultaneously receiving HAART if the H

Mechanisms for pumping blood, Normal 0 false false false ...

Normal 0 false false false EN-IN X-NONE X-NONE MicrosoftInternetExplorer4

Explain free water - water found in food, Explain Free Water - Water Found ...

Explain Free Water - Water Found in Food? Water which is bound by such minute forces, that its vapour pressure is equal to the vapour pressure of pure water. It can be found as

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd