Structure-activity relationships

Structure-activity relationships may be useful to increase the weight-of-evidence or human health hazards identification. Where classes of compounds are of interest (e.g., polycyclic aromatic hydrocarbons, polychlorinated biphenyls and dioxins) and where adequate toxicological data are available  on  one or more members of the class, a toxic equivalence approach may be useful to predict the human health hazard associated with exposure  to  other members of the class.