Explain skeletal muscle, Biology

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Explain Skeletal muscle

Skeletal muscle has low activity of glucose-6-phosphate dehydogenase. Yet, like most other  tissues  it can synthesize ribose-5-phosphate.  This  is.probably accomplished  by a reversal  of  the shunt pathway utilizing fructose-6-phosphate and glyceraldehyde-3- phosphate and  the enzymes transketolase  and  transaldolase. Both fructose-6-phosphate and glyceraldehyde-3-phosphate  are utilized  in Embden-Meyerhof pathway for  glycolysis. Hence it is not necessary  to have a completely functioning HMP pathway  for  a  tissue to synthesize  ribose-5-phosphate.

 


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