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Explain Skeletal muscle
Skeletal muscle has low activity of glucose-6-phosphate dehydogenase. Yet, like most other tissues it can synthesize ribose-5-phosphate. This is.probably accomplished by a reversal of the shunt pathway utilizing fructose-6-phosphate and glyceraldehyde-3- phosphate and the enzymes transketolase and transaldolase. Both fructose-6-phosphate and glyceraldehyde-3-phosphate are utilized in Embden-Meyerhof pathway for glycolysis. Hence it is not necessary to have a completely functioning HMP pathway for a tissue to synthesize ribose-5-phosphate.
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K.L. is a 30-year-old Caucasian male was brought to Emergency Department (ED) after a bicycle accident. He was hit from behind by a compact car traveling at 35 miles per hour. On
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