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A classical secretory protein vary from a cytosolic protein by having a sequence about 13-35 amino acids long at its N-terminal end called as a signal peptide or signal sequence. The signal peptides of various secretory proteins vary in amino acid sequence but there are some regular features, for instance the center of the sequence commonly having of 10-15 hydrophobic amino acids. An signal hypothesis was proposed from early work in this area and predicted in which the signal peptide directs the secretory protein to the RER membrane and so goals the protein to cross into the RER lumen and be exported. The signal hypothesis has been explained to apply to protein secretion in plant, animal and bacterial cells.
Explain Nephrotoxicity Nephrotoxicity is the major dose-limiting toxicity of amphotericin B deoxycholate; sodium loading with normal saline may prevent or ameliorate it and is
Define Role of Iron in Controlling Gene Expression? Iron metabolism is regulated by a complex co-ordinate mechanism. Recent evidence supports specific past-transcriptional mech
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Give a detailed description of stereoblastula, please ?#
A biologist examines a series of cells and counts 140 cells in interphase, 10 cells in metaphase, 4 cells in anaphase and 7 cells in telophase. if complete cell cycle requires 24 h
At 1 AM, a healthy squid giant axon is placed in a bath of normal squid physiological extracellular saline and is internally perfused with normal squid intracellular saline. I
Explain Precautions for Detection of Metanil Yellow? 1. One should be careful while using concentrated HCl otherwise it may result in burn. 2. Amount of concentrated HCl in
Ivory was much in demand for production of a variety of jewellery and artifacts in the past. Reptile leather from crocodiles, lizards and snakes has quite a high demand for manufac
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