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A classical secretory protein vary from a cytosolic protein by having a sequence about 13-35 amino acids long at its N-terminal end called as a signal peptide or signal sequence. The signal peptides of various secretory proteins vary in amino acid sequence but there are some regular features, for instance the center of the sequence commonly having of 10-15 hydrophobic amino acids. An signal hypothesis was proposed from early work in this area and predicted in which the signal peptide directs the secretory protein to the RER membrane and so goals the protein to cross into the RER lumen and be exported. The signal hypothesis has been explained to apply to protein secretion in plant, animal and bacterial cells.
site of fertilistion in human
Q. Can you explain about Cardiomyopathies? Cardiomyopathy is a primary disorder of heart muscle that may cause cardiac dysfunction and is not related to any obvious disease pr
A 19 year old model for Glamour magazine tripped over an extension cord causing injury to her epidermis. She is afraid the injury will leave a scar. Based on your knowledge of rege
N e wcastle disease / Ranikhet disease (ND/RD) This disease is caused by Newcastle disease virus (NDV) belonging to the genus Paramyxovirus of the family Paramyxoviridae. Alo
MR means medical representative. Medical rep has to sell products of pharma companies or drug manufacturers. He has to go to doctors and medical shops to sell drugs and promote dru
MECHANISM OF URINE FORMATION - Production of urine is uripoisis or diuresis. First of all it was explained by Kushney. Nephron separates acidic urine from basic blood, so ma
Explain Extra Cardiac Conduit Fontan ? This can be done with or without cardipulmonary bypass. First step is to make a bi-directional Glenn shunt. The main pulmonary artery is
What is ADP phosphorylation? What respectively are photophosphorylation and oxidative phosphorylation? ADP phosphorylation is the addition of one inorganic phosphate in the mol
Digestive Enzymes Now let us consider the general principles of digestion that are applicable t6all animals. We will start with the digestive enzymes that breakdown the large
Plant Responses to Specific Stress Conditions By now you must have developed a feeling that plants are organised to function optimally under a set of environmental conditions.
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