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A classical secretory protein vary from a cytosolic protein by having a sequence about 13-35 amino acids long at its N-terminal end called as a signal peptide or signal sequence. The signal peptides of various secretory proteins vary in amino acid sequence but there are some regular features, for instance the center of the sequence commonly having of 10-15 hydrophobic amino acids. An signal hypothesis was proposed from early work in this area and predicted in which the signal peptide directs the secretory protein to the RER membrane and so goals the protein to cross into the RER lumen and be exported. The signal hypothesis has been explained to apply to protein secretion in plant, animal and bacterial cells.
What is Diagnosis of Heart Disease in the Newborn ? Clinical diagnosis of heart disease in the newborn can be quite challenging. Manifestations of potentially life threatening
T ypes of hormones - (i) Releasing and Inhibitory hormones - Hormones of hypothalamus and kidney (renin) which control secretion of trophic hormones. (ii) Trophic hormon
Microevolution is: the change in allele frequency in a population. Cannot occur if genetic equilibrium is reached. Results in the formation of a new species. Is influenced by mutat
discuss the merits nd demerits of five kingdom classification.
The aqueous solution with the lowest pH is: Select one: a. 0.01 M HCl. b. 0.1 M acetic acid (pKa = 4.86). c. 0.1 M formic acid (pKa = 3.75). d. 0.1 M HCl. e. 10 t
R in d e rp es t It is also known as cattle plague resulting in high fever, diarrhoea and high mortality rates. In year 2006, OIE has declared that India is free from rin
Alzheimer's disease - a devastating brain disease which gradually ruins the , thinking skills, patient's memory and ultimately the ability to perform the simpl
Determine the term Memory - Psychological tests The acquisition, reaction, and retrieval of new information is a domain of much importance in infants and young children at risk
Why Protein requirements of athletes get increased? Protein requirements of athletes, particularly those engaged in strength and power events, may be increased above those of s
Q. What is the significance of water for enzymatic activity? Enzymes, Biological catalysts, depend on water to reach their substrates and bind to them. There is no enzymatic ac
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