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A classical secretory protein vary from a cytosolic protein by having a sequence about 13-35 amino acids long at its N-terminal end called as a signal peptide or signal sequence. The signal peptides of various secretory proteins vary in amino acid sequence but there are some regular features, for instance the center of the sequence commonly having of 10-15 hydrophobic amino acids. An signal hypothesis was proposed from early work in this area and predicted in which the signal peptide directs the secretory protein to the RER membrane and so goals the protein to cross into the RER lumen and be exported. The signal hypothesis has been explained to apply to protein secretion in plant, animal and bacterial cells.
Explain Indications for Surgery of Total Anomalous pulmonary Venous Connection ? Once TAPVC is diagnosed in a neonate with symptoms, operation should be undertaken immediately.
Mitral Valve Replacement : Patients who require surgery and are not candidates for BMV, CMV or OMV should have mitral valve replacement (MVR). Types of Surgery for Mitra
Explain Water as a lubricant? All fluids have lubricating as they can make it easier for the solid materials to slip over one another. Water-based fluids act as lubricants in
The pentose phosphate pathway also called as the phosphogluconate pathway and the hexose monophosphate shunt is a procedure which gives pentoses 5-carbon sugars and NADPH. There ar
Define About the Sterols - Non Glyceride Fractions? These constitule a major proportion of the non-glyceride component while tocopherols, carotene pigments and flavour compound
Characteristic features of Phylum Cnidaria All are aquatic animals. Radial or biradial symmetry around an oro-aboral axis, but no head. Diploblastic, with an epidermi
Meninges (Singular-Meninx) - Ceverings of brain. By infection in meninges meningitis or brain fever is caused. These menings are internally lined by squamous epitheliu
Reproductive health disorders to dairy livestock accounts to a loss of about Rs 30,000- 50,000 crore annually to the nation. Better herd management can minimize the occurrence of d
What is protein denaturation? Is there any change in the primary structure when a protein is denatured? Secondary, tertiary and quaternary structures of proteins are spatial st
why is epidermis peeledsuggest why a marine amoeba does not have a contractile vacuole
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