Explain signal hypothesis, Biology

Assignment Help:

A classical secretory protein vary from a cytosolic protein by having a sequence about 13-35 amino acids long at its N-terminal end called as a signal peptide or signal sequence.  The  signal  peptides  of  various  secretory  proteins  vary  in amino  acid  sequence  but  there  are  some  regular  features,  for  instance  the center of the sequence commonly having of 10-15 hydrophobic  amino acids.   An signal hypothesis was proposed from early work in this area and predicted in which the signal  peptide  directs  the secretory  protein  to the RER  membrane  and  so goals  the  protein  to  cross  into  the  RER  lumen  and  be  exported.  The signal hypothesis has been explained to apply to protein secretion in plant, animal and bacterial cells.

 


Related Discussions:- Explain signal hypothesis

What do you understand by metanephridia, What do you understand by Metaneph...

What do you understand by Metanephridia? An excretory-osmoregulatory organ comprising a ciliated funnel, nephrostome, connected to tubules that lead to the external nephridiopo

What are the problems regarding terrestrial environment, Q. What are the pr...

Q. What are the problems that vertebrates needed to solve to adapt to the terrestrial environment since they came from the aquatic habitat? How evolution does solve those problems?

Define obesity - excessive fat intake, Define Obesity - Excessive Fat Intak...

Define Obesity - Excessive Fat Intake? In obesity, cutting down total energy intake or increasing output to ensure energy balance is the basic principle of prevention. Fat bein

Disposal of microorganisms, Disposal : You must always sterilize cultures ...

Disposal : You must always sterilize cultures and contaminated instruments and glassware before disposing them of or before washing-up. Usually, you can do this by autoclaving or

Determine number of sucrose molecules in the solution, Determine number of ...

Determine number of sucrose molecules in the solution When a solid is dissolved in a volatile solvent the vapour pressure of the solution is less than the vapour pressure of th

Bque, what is working of heart

what is working of heart

In which lysosomic enzymes play a fundamental role, Q. What are the various...

Q. What are the various biological examples in which lysosomic enzymes play a fundamental role? The remodelation of the osseous tissue, the function of the elimination of the t

Define about the excretion of calcium, Define about the Excretion of Calciu...

Define about the Excretion of Calcium? Calcium is excreted approximately in equal amounts in urine and through intestinal secretions. Bile and other secretions into the intest

Trichomonas vaginalis - protozoan, Trichomonas vaginalis - Protozoan T...

Trichomonas vaginalis - Protozoan This cosmopolitan protozoan lives exclusively in the female vagina and male urethra or prostate. It causes a mild disease called trichomonas

Comparing the dna of a calfs liver and thymus, When comparing the DNA of a ...

When comparing the DNA of a calfs liver and thymus, which would be predicted to have more DNA and why? What are the differences of the DNA between the two?

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd