Explain signal hypothesis, Biology

Assignment Help:

A classical secretory protein vary from a cytosolic protein by having a sequence about 13-35 amino acids long at its N-terminal end called as a signal peptide or signal sequence.  The  signal  peptides  of  various  secretory  proteins  vary  in amino  acid  sequence  but  there  are  some  regular  features,  for  instance  the center of the sequence commonly having of 10-15 hydrophobic  amino acids.   An signal hypothesis was proposed from early work in this area and predicted in which the signal  peptide  directs  the secretory  protein  to the RER  membrane  and  so goals  the  protein  to  cross  into  the  RER  lumen  and  be  exported.  The signal hypothesis has been explained to apply to protein secretion in plant, animal and bacterial cells.

 


Related Discussions:- Explain signal hypothesis

How to facilitate information transfer during transcription, How is energy ...

How is energy used to facilitate information transfer during transcription?

Compare and contrast enantiomers in relation to sugars, Compare and contras...

Compare and contrast enantiomers, epimers, and anomers, specifically in relation to sugars.

Enzyme specificity, Enzyme Specificity Enzymes play a critical role wit...

Enzyme Specificity Enzymes play a critical role within biological systems through helping reactions to occur beneath the commonly mild conditions in that organisms live. Enzyme

Gastrulation, Gastrulation  Gastrulation is the process through whic...

Gastrulation  Gastrulation is the process through which the presumptive areas of organ specific rudimetns present on the surface of blastula move to their specific position

What are the maximum crop yields, What are the Maximum Crop Yields   Mi...

What are the Maximum Crop Yields   Mitscherlich conducted a large number of experiments with different plants, making use of pots 20 cm in diameter and 20 cm in depth. By addin

Medical management of chronic renal failure, Medical Management   In ch...

Medical Management   In chronic  renal failure  there  is irreversible renal failure. The goals of medical management are:   To promote maximal  renal  function  To ma

What happens to the blood when it passes through the lungs, Q. Do the arter...

Q. Do the arteries that carry blood from the heart to the lungs contain arterial or venous blood? What happens to the blood when it passes through the lungs? Arteries of the pu

How is snow - blindness caused in humans, How is snow - blindness caused in...

How is snow - blindness caused in humans? a) Mention the site where syngamy happens in amphibians and reptiles correspondingly.

Genetics, what is a homologous chromosome

what is a homologous chromosome

How genetic predisposition causing the underweight, How Genetic Predisposit...

How Genetic Predisposition causing the underweight? Mother's Health Status; Poor nutritional status of the girl child coupled with under nutrition during pregnancy results in L

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd