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A classical secretory protein vary from a cytosolic protein by having a sequence about 13-35 amino acids long at its N-terminal end called as a signal peptide or signal sequence. The signal peptides of various secretory proteins vary in amino acid sequence but there are some regular features, for instance the center of the sequence commonly having of 10-15 hydrophobic amino acids. An signal hypothesis was proposed from early work in this area and predicted in which the signal peptide directs the secretory protein to the RER membrane and so goals the protein to cross into the RER lumen and be exported. The signal hypothesis has been explained to apply to protein secretion in plant, animal and bacterial cells.
Explain Adverse Effects Fluconazole is generally well tolerated. Gastrointestinal distress and rash can happen. Stevens-Johnson syndrome, anaphylaxis and hepatic necrosis have
Define Strategies for to overcome from alzheimer's disease? Some of these, based on the stage of the disease and individual needs are: a. supervising meal times with minimal
Why do fats have thermal isolation properties? Triglycerides are weak heat conductors and in addition they form thick layers of fat tissue when accumulated by the organism. Tha
The vascular tone increases as the arterial size decreases. The tone at any time reflects the effects of excitory and inhibitory pathways. Neurotransmitters, physical forces like s
Lactate dehydrogenase (LDH) is one of the important enzymes in glycolysis which catalyzes the interconversion of pyruvate and lactate as follows: Functional lactate d
Q. Why does thymine replace uracil in DNA? The difference between DNA and RNA is existence of a hydroxyl (-OH) group on 2' carbon of the ribose sugar in the backbone. Removal o
explain the relationship between concentration gradient and active and passive transport
The method of recombination or crossing-over Which of the following is a false statement regarding the method of recombination or crossing-over? A. Crossing-over takes place
what is process of ultrafilteration involved?
L e p t o s p i r o s i s It is zoonotic disease characterized by interstitial nephritis, haemolytic anaemia and abortions. E t iology : The disease i
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