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A classical secretory protein vary from a cytosolic protein by having a sequence about 13-35 amino acids long at its N-terminal end called as a signal peptide or signal sequence. The signal peptides of various secretory proteins vary in amino acid sequence but there are some regular features, for instance the center of the sequence commonly having of 10-15 hydrophobic amino acids. An signal hypothesis was proposed from early work in this area and predicted in which the signal peptide directs the secretory protein to the RER membrane and so goals the protein to cross into the RER lumen and be exported. The signal hypothesis has been explained to apply to protein secretion in plant, animal and bacterial cells.
What is the autotrophic hypothesis on the origin of life? An autotrophic hypothesis on the origin of life asserts that the first living beings on earth were producers of their
why frog respire through skin
Iron deficiency should be treated with supplemental iron. • Osteoporosis should be treated with calcium and vitamin D supplements. • Depending on individual factors, patien
Q. Pathophysiology of mitral stenosis? Normally there is no pressure gradient between left atrium and the left ventricle during diastole. However, as the valve orifice size dec
Cross-Pollination - Types of Pollination In this kind of pollination the pollen from anther of one individual is transferred to the stigma of another individual of the same sp
In a cohort study that found an association between alcohol consumption and bladder cancer, 20,000 middle-aged men were asked about their drinking habits and then tracked for five
Q. Do the phylogenetically proximal species have cells with proximal chromosome counts? The number of chromosomes typical of each species is proximal for phylogenetically proxi
Lysosomes Lysosomes are small vesicles which are bounded by a single membrane & contain hydrolytic enzymes in the form of minute crystalline or semi crystalline granules of
Renal parenchymal disease is the commonest cause of secondary hypertension. Hypertensive and diabetic nephropathy and chronic glomerulonephritis are the main causes. Eventually, t
ADP-ATP system of energy exchange : In 1929 Lohmann, Fiske and subbarow published their discovery that the energy exchanges compounds in all biological systems are t
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