Explain signal hypothesis, Biology

Assignment Help:

A classical secretory protein vary from a cytosolic protein by having a sequence about 13-35 amino acids long at its N-terminal end called as a signal peptide or signal sequence.  The  signal  peptides  of  various  secretory  proteins  vary  in amino  acid  sequence  but  there  are  some  regular  features,  for  instance  the center of the sequence commonly having of 10-15 hydrophobic  amino acids.   An signal hypothesis was proposed from early work in this area and predicted in which the signal  peptide  directs  the secretory  protein  to the RER  membrane  and  so goals  the  protein  to  cross  into  the  RER  lumen  and  be  exported.  The signal hypothesis has been explained to apply to protein secretion in plant, animal and bacterial cells.

 


Related Discussions:- Explain signal hypothesis

Introduction to heart surgery, INTRODUCTION :  It took just hundred years ...

INTRODUCTION :  It took just hundred years for cardiac surgery to advance to what it is today. Before 1896, surgeons considered heart to be "inviolable" and it was stated that ope

How to use subcellular fractionation and a western blot, A virus capsid con...

A virus capsid containing vimentin, your protein of interest, gets into the cell nucleus and is broken down with the DNA being released. It is unknown whether the capsids themselve

Omni science valve-types of valves, Omni Science Valve :  Thi...

Omni Science Valve :  This is another type of tilting disc valve available from 1978. The cage is made of titanium and disc out of pyrolitic carbon. There have been a

Explain hiv/aids, Explain HIV/AIDS HIV/AIDS is another example of  chro...

Explain HIV/AIDS HIV/AIDS is another example of  chronic infections.  Its existence was discovered recently in 1981. The spread  of  HIV infection  is widespread  and  can  pro

Endocrine glands - kidney, KIDNEY S - Origin . They develop from the ...

KIDNEY S - Origin . They develop from the mesoderm of the embryo. The kidneys secrete three hormones: renin, erythropoetin and calcitriol. (i) Renin . Whenever the rat

The social environment - stress of hospitalization, The Social Environment ...

The Social Environment   When the child is admitted to the hospital his social environment is totally changed and all health team members are strangers for him. It is your resp

Hypolimnion - summer stratification, Hypolimnion - Summer Stratification ...

Hypolimnion - Summer Stratification This zone forms the bottom layer which is deep, cold and non- circulating. The hypolimnion is generally rich in nutrients though its oxygen

Define ergogenic and for training and competition, Define Ergogenic and for...

Define Ergogenic and for training and competition? There is always our desire to work with the body more .than its capability. This is more so in case of athletes. They wish to

In how many form glycogen synthase exists, Glycogen  synthase exists  in t...

Glycogen  synthase exists  in two forms:   the phosphorylated form designated  as  'D' form is the  inactive one and  the dephoshorylated form designated as  'I'  form is the activ

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd