Explain signal hypothesis, Biology

Assignment Help:

A classical secretory protein vary from a cytosolic protein by having a sequence about 13-35 amino acids long at its N-terminal end called as a signal peptide or signal sequence.  The  signal  peptides  of  various  secretory  proteins  vary  in amino  acid  sequence  but  there  are  some  regular  features,  for  instance  the center of the sequence commonly having of 10-15 hydrophobic  amino acids.   An signal hypothesis was proposed from early work in this area and predicted in which the signal  peptide  directs  the secretory  protein  to the RER  membrane  and  so goals  the  protein  to  cross  into  the  RER  lumen  and  be  exported.  The signal hypothesis has been explained to apply to protein secretion in plant, animal and bacterial cells.

 


Related Discussions:- Explain signal hypothesis

Fowl typhoid, F o wl typhoid Fowl typhoid is caused by Salmonella G...

F o wl typhoid Fowl typhoid is caused by Salmonella Gallinarum , a Gram negative bacillus in the family enterobacteriaceae (serogroup D). Chickens are the natural hosts fo

Conjugation – protozoan, Conjugation – Protozoan Conjugation is charac...

Conjugation – Protozoan Conjugation is characteristic of ciliates. The details vary from species to species. The general features can be observed in Paramecium sps. which has

Explain inborn errors of metabolism, Q.  Explain Inborn Errors of Metabolis...

Q.  Explain Inborn Errors of Metabolism? Some of the disorders caused by inborn error of metabolism namely phenylketonuria, tyrosinemia, maple syrup urine disease, homocystinur

Biochemistry, tertiary structure of protein

tertiary structure of protein

Metabolism, METABOLISM  - Word given by Shwann . It includes bio-ch...

METABOLISM  - Word given by Shwann . It includes bio-chemical reactions occur in body may be constructive or destructive. It includes -                         Anabo

Supportive therapy for diabetes patient, Q. Supportive Therapy for diabetes...

Q. Supportive Therapy for diabetes patient? Certain foods, part of food or food components have been found to be beneficial in managing hyperglycemia. Most of these have been i

Ecosystem, ECOSYSTEM Plants, animals and human beings live in association...

ECOSYSTEM Plants, animals and human beings live in association with a wide variety of other plants and animals. These communities of organisms are not mere ad boc collections of

What are the frequencies of the s, Platinum color in foxes is produced by h...

Platinum color in foxes is produced by heterozygous genotype Ss, and silver foxes are the genotype SS. The genotype ss is lethal, and the fox dies in early embryonic development. I

Enzyme-controlled reaction, If an enzyme-controlled reaction normally takes...

If an enzyme-controlled reaction normally takes place at 10ºC, in general terms how will the reaction be affected by  (a) a fall in temperature to 2°C , (b) a rise in temperature t

What are the differences between astral and anastral mitosis, What are the ...

What are the differences between astral and anastral mitosis? Astral mitosis is that in which there is structure of the aster, a structure made by the centrioles. Anastral mito

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd