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A classical secretory protein vary from a cytosolic protein by having a sequence about 13-35 amino acids long at its N-terminal end called as a signal peptide or signal sequence. The signal peptides of various secretory proteins vary in amino acid sequence but there are some regular features, for instance the center of the sequence commonly having of 10-15 hydrophobic amino acids. An signal hypothesis was proposed from early work in this area and predicted in which the signal peptide directs the secretory protein to the RER membrane and so goals the protein to cross into the RER lumen and be exported. The signal hypothesis has been explained to apply to protein secretion in plant, animal and bacterial cells.
EVOLUTION OF MAN - Mammals evolved from primitive reptiles (therapsida) in Triassic period, about 210 million years ago. Mammals existed as inconspicuous group of small
How Hormonal Status affects the bmr? Thyroid status may be most important factor and can make differences of up to plus or minus 50% for hyperthyroidism or hypothyroidism, resp
Reversible airways obstructive disease, advanced heart block, or episodic decompensation. Vasodilators Agents that dilate arteriolar smooth muscle and lower peripheral vascu
Q. What do you mean by Diabetes Mellitus? Diabetes Mellitus as you know is a metabolic disorder, which is characterized by high blood sugar. It is a chronic disease condition,
Ancillary Accomodation: Ward KitchenIPantry: It should have large sink and drain board along with fly proof door. If the food is received from central kitchen and tray pre
in sericulture industry do which stages of silkworm weaver buy? why do they do so?
Cheese Production Cheese production involves the conversion of the milk protein, k-casein to paracasein by a defined, limited hydrolysis, catalysed by chymosin (rennin). In the
Describe DNA replication in details? Replication : DNA replicates itself by first breaking the hydrogen bonds between the nitrogen base pairs, and "unzips" itself into two s
Why is the fish circulation classified as a simple and complete circulation? Complete circulation is that in which there is no mixture of venous blood and arterial blood. As ci
how temperature acts as limiting factor explain?
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