Explain rifabutin, Biology

Assignment Help:

Explain Rifabutin

Two alternative regimens are based on the fact that rifabutin appears to be as effective as rifampin against TB, and has less effect on protease inhibitor levels. The first substitutes low-dose rifabutin (150 mg once/day or 300 mg 3x/week) for rifampin in the standard regimen (i.e., isoniazid, rifabutin, pyrazinamide and ethambutol) and uses higher than usual doses of indinavir (Crixivan) or nelfinavir (Viracept), or standard doses of amprenavir (Agenerase) or fos amprenavir (Lexiva)  as the protease inhibitor.

The second decreases the rifabutin dose further to 150 mg every other day or 3 times weekly and gives it with standard doses of atazanavir  (Reyataz), ritonavir/lopinavir (Kaletra) or ritonavir alone or combined with other protease inhibitors. Saquinavir (Fortovase, Invirase) alone should not be used. If the HAART regimen contains nevirapine, the usual dose of rifabutin should be used. Higher rifabutin doses (450-600 mg daily) are needed if the HAART regimen contains efavirenz.

 


Related Discussions:- Explain rifabutin

Cooking of vitamin c-containing foods, Q. Why isn't the cooking of vitamin ...

Q. Why isn't the cooking of vitamin C-containing foods appropriate for vitamin C supply? To obtain vitamin C, for instance, from an orange dessert, the vitamin- containing food

Traditionally value biological resources, However, according to conventiona...

However, according to conventional principles of economic analysis it is necessary that a resource is used for it to acquire a value. Consequently economists traditionally value bi

Invertebrate zoology, give an example invertebrate phylum/phyla for protopl...

give an example invertebrate phylum/phyla for protoplasmic grade organization

Phylum mollusca, what is salen and its characterstics

what is salen and its characterstics

Explain the parts of plasma membrane, The plasma membrane consists mainly o...

The plasma membrane consists mainly of: 1. Phospholipids embedded in a protein bilayer 2. Proteins embedded in a phospholipid bilayer 3. Proteins embedded in a polymer of

Define the characteristics that are seen in rickets, Define the characteris...

Define the characteristics that are seen in Rickets? The following characteristics are seen in fully developed cases of rickets: 1) In case of young infants, delayed closure

Chlamydiosis-diagnosis, Diagnosis Clinical signs: In most of the case...

Diagnosis Clinical signs: In most of the cases in initial stages like bacterial infections there is leucocytosis with neutrophilia, which at later stages of the disease may c

Define solvent chemical potentials from phase equilibria, Define Solvent Ch...

Define Solvent Chemical Potentials from Phase Equilibria? Previously explained how we can evaluate the activity coefficient γ m,B of a nonelectrolyte solute of a binary soluti

Determine the proecss of contrast sense, Contrast sense Sense of contr...

Contrast sense Sense of contrast is the ability to perceive slight changes in luminance between regions which are not separated by definite borders. This is as important as to

Head stream of highland brook zone, Head stream of Highland brook zone ...

Head stream of Highland brook zone This is formed by a number of small streams, which originate from a marsh, a spring or a glacier. This is a small shallow zone with an irreg

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd