Explain rifabutin, Biology

Assignment Help:

Explain Rifabutin

Two alternative regimens are based on the fact that rifabutin appears to be as effective as rifampin against TB, and has less effect on protease inhibitor levels. The first substitutes low-dose rifabutin (150 mg once/day or 300 mg 3x/week) for rifampin in the standard regimen (i.e., isoniazid, rifabutin, pyrazinamide and ethambutol) and uses higher than usual doses of indinavir (Crixivan) or nelfinavir (Viracept), or standard doses of amprenavir (Agenerase) or fos amprenavir (Lexiva)  as the protease inhibitor.

The second decreases the rifabutin dose further to 150 mg every other day or 3 times weekly and gives it with standard doses of atazanavir  (Reyataz), ritonavir/lopinavir (Kaletra) or ritonavir alone or combined with other protease inhibitors. Saquinavir (Fortovase, Invirase) alone should not be used. If the HAART regimen contains nevirapine, the usual dose of rifabutin should be used. Higher rifabutin doses (450-600 mg daily) are needed if the HAART regimen contains efavirenz.

 


Related Discussions:- Explain rifabutin

Oogenesis in mammals, Oogenesis in Mammals In mammals also the oogoni...

Oogenesis in Mammals In mammals also the oogonial cells are derived from primordial germ cells. The multiplication phase, that is all of the oogonial divisions and transforma

Law of diminishing return, Law of Diminishing Return A German scientis...

Law of Diminishing Return A German scientist Mitscherlich calculated the effect of different quantities of various growth factors on the yield of plants by means of a mathemat

Determine the steps for withdrawing the insulin, Determine the Steps for Wi...

Determine the Steps for Withdrawing the Insulin The important thing about measuring a dose is to use the front of the plunger not the back - Check doctor's prescription.

Explain the effect of deficiency of copper in human, Explain the effect of ...

Explain the effect of Deficiency of Copper in Human? Owing to the remarkable homeostatic mechanisms, copper deficiency in humans is rare. However, copper deficiency has been re

Heparin, HE P ARIN It is highly sulphated mucopolysaccharide made ...

HE P ARIN It is highly sulphated mucopolysaccharide made of alternate units of glucosamine and glucuronic acid. Heparin is mainly produced by liver and mast cells. I

Define interaction of niacin with other nutrients, Define Interaction of ...

Define Interaction of niacin with other Nutrients? You may recall reading earlier that trypotophan present in dietary proteins is converted to niacin. There is an interdepend

Demonstrate the cell membrane, While working in the lab, you isolate a cell...

While working in the lab, you isolate a cell from a mouse and a cell from a human and fuse them together to form a live, hybrid cell. You then use an antibody that recognizes all m

Candidiasis, Candidiasis Candidiasis (Moniliasis) is a disease of man, ...

Candidiasis Candidiasis (Moniliasis) is a disease of man, animals and birds and is caused chiefly by Candida albicans. Crop mycosis (thrush) of poultry is caused by C. albicans

Describe cytokinesis in a plant cell, Describe cytokinesis in a plant cell....

Describe cytokinesis in a plant cell. Vesicles produced by the Golgi apparatus fuse at  the midline of the cell to form the cell plate, a  cell wall that elongates to divide th

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd