Explain rifabutin, Biology

Assignment Help:

Explain Rifabutin

Two alternative regimens are based on the fact that rifabutin appears to be as effective as rifampin against TB, and has less effect on protease inhibitor levels. The first substitutes low-dose rifabutin (150 mg once/day or 300 mg 3x/week) for rifampin in the standard regimen (i.e., isoniazid, rifabutin, pyrazinamide and ethambutol) and uses higher than usual doses of indinavir (Crixivan) or nelfinavir (Viracept), or standard doses of amprenavir (Agenerase) or fos amprenavir (Lexiva)  as the protease inhibitor.

The second decreases the rifabutin dose further to 150 mg every other day or 3 times weekly and gives it with standard doses of atazanavir  (Reyataz), ritonavir/lopinavir (Kaletra) or ritonavir alone or combined with other protease inhibitors. Saquinavir (Fortovase, Invirase) alone should not be used. If the HAART regimen contains nevirapine, the usual dose of rifabutin should be used. Higher rifabutin doses (450-600 mg daily) are needed if the HAART regimen contains efavirenz.

 


Related Discussions:- Explain rifabutin

What are Modes of Nutrition, What is Nutrition? Explain types of nutrition?...

What is Nutrition? Explain types of nutrition? Nutrition - Taking Nutrients from environment Nutrients - Substances which are needed for the sources of chemical potential en

Show examples of annelids, Q What are the few examples of annelids? Ear...

Q What are the few examples of annelids? Earthworms, lugworms and leeches. Q. Which are the morphological features that differentiate the beings of the phylum Annelida from

Into which phyla is the fungi kingdom divided, Fungi are classified in thei...

Fungi are classified in their own kingdom. Into which phyla is the fungi kingdom divided? Into which of those phyla are mushrooms classified? The kingdom fungi is separated in

Describe the metabolism of lipids, Q. Describe the metabolism of lipids? ...

Q. Describe the metabolism of lipids? Fats are split into fatty acids and glycerol by the enzyme. They are absorbed in small intestine and recombined into fats. It is stored in

Show Relation between tissue and the implant material, Relation between Tis...

Relation between Tissue and the implant material The biologic interaction between the tissue and the implant material at an  interface may result in a variety of phenomena such

Amoeboid protozoan, Amoeboid Protozoan Amoeboid protozoan are distingu...

Amoeboid Protozoan Amoeboid protozoan are distinguished by the presence of flowing extensions of their body known as pseudopodia. These are used for feeding and locomotion. Th

Fats are essential for meeting nutritional need of essential, Why Fats are ...

Why Fats are essential for meeting nutritional need of essential? Fats are essential for meeting nutritional needs of essential, fatty acids like linoleic acid (n-6) and alpha

Write in 3-4 lines about foot examination, Write in 3-4 lines about foot ex...

Write in 3-4 lines about foot examination Foot ulceration and amputation are common and major causes of morbidity and disability in people with diabetes. Skin integrity should

Define causes of vitamin a deficiency - inadequate diet, Define Causes of V...

Define Causes of Vitamin A Deficiency - Inadequate diet? A child is born with poor stores of vitamins and minerals due to maternal malnutrition. Diets of pregnant women are def

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd