Explain rifabutin, Biology

Assignment Help:

Explain Rifabutin

Two alternative regimens are based on the fact that rifabutin appears to be as effective as rifampin against TB, and has less effect on protease inhibitor levels. The first substitutes low-dose rifabutin (150 mg once/day or 300 mg 3x/week) for rifampin in the standard regimen (i.e., isoniazid, rifabutin, pyrazinamide and ethambutol) and uses higher than usual doses of indinavir (Crixivan) or nelfinavir (Viracept), or standard doses of amprenavir (Agenerase) or fos amprenavir (Lexiva)  as the protease inhibitor.

The second decreases the rifabutin dose further to 150 mg every other day or 3 times weekly and gives it with standard doses of atazanavir  (Reyataz), ritonavir/lopinavir (Kaletra) or ritonavir alone or combined with other protease inhibitors. Saquinavir (Fortovase, Invirase) alone should not be used. If the HAART regimen contains nevirapine, the usual dose of rifabutin should be used. Higher rifabutin doses (450-600 mg daily) are needed if the HAART regimen contains efavirenz.

 


Related Discussions:- Explain rifabutin

Male reproductive system - penis, PENIS - Intromittent organ. Erecti...

PENIS - Intromittent organ. Erectile, its apex is penis glanse. Covered by prepuce (part of skin). Main function is insemination (To transfer sperms in vagina in deep).

List down the various mycotoxins associated with food, Q. List down the var...

Q. List down the various mycotoxins associated with food? Mycotoxins associated with foods are: • Aflatoxins (produced by Aspergillus flavus) • Ochratoxin (produced

Titration of inverted honey solution, Titration of inverted honey solution ...

Titration of inverted honey solution It involves the titration of the inverted honey solution. Carry out the titration in the following manner. 1) In a conical flask take 5

Give the causative organism of bacillary dysentery, Give the causative orga...

Give the causative organism and symptoms of Bacillary Dysentery • Bacillary dysentery is caused by  Shigella sp. (Shigella sonnei, S. dysenteraei). Incubation period is

Can you explain bacillus cereus poisoning, Q. Can you explain Bacillus Cere...

Q. Can you explain Bacillus Cereus Poisoning? Ans. Bacillus cereus poisoning is caused by the organism which is a large (3-5 pm long .and 1-4 pm wide), gram po%tive,

What is the etiological agent of amebiasis, What is the etiological agent o...

What is the etiological agent of amebiasis? How is it transmitted and what are the typical manifestations of the disease? Amebiasis is caused by the protozoan Entamoeba histoly

Explain the presumptive test - most probable number test, Explain the Presu...

Explain the Presumptive Test - Most Probable Number Test? The Presumptive test is used to detect and estimate coliform population of a water sample. This test is carried out by

Snake bite, S n ake bite Biting by a poisonous snake is manifested by...

S n ake bite Biting by a poisonous snake is manifested by clinical findings of local swelling and nervous symptoms. E t iology: The poisonous snakes have different typ

Explain performance testing of fats and oil, Explain performance testing of...

Explain performance testing of fats and oil In these cases, performance testing is the only means for evaluating the ability of fat or oil to perform the desired functions in a

Conventional agro-industrial oilseed cakes, Conventional agro-industrial oi...

Conventional agro-industrial oilseed cakes Groundnut meal: It is readily available protein source byproduct from the extraction of groundnut, which is a popular human food i

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd