Explain rifabutin, Biology

Assignment Help:

Explain Rifabutin

Two alternative regimens are based on the fact that rifabutin appears to be as effective as rifampin against TB, and has less effect on protease inhibitor levels. The first substitutes low-dose rifabutin (150 mg once/day or 300 mg 3x/week) for rifampin in the standard regimen (i.e., isoniazid, rifabutin, pyrazinamide and ethambutol) and uses higher than usual doses of indinavir (Crixivan) or nelfinavir (Viracept), or standard doses of amprenavir (Agenerase) or fos amprenavir (Lexiva)  as the protease inhibitor.

The second decreases the rifabutin dose further to 150 mg every other day or 3 times weekly and gives it with standard doses of atazanavir  (Reyataz), ritonavir/lopinavir (Kaletra) or ritonavir alone or combined with other protease inhibitors. Saquinavir (Fortovase, Invirase) alone should not be used. If the HAART regimen contains nevirapine, the usual dose of rifabutin should be used. Higher rifabutin doses (450-600 mg daily) are needed if the HAART regimen contains efavirenz.

 


Related Discussions:- Explain rifabutin

Male reproductive disorders-preputial prolapse, Preputial prolapse Thi...

Preputial prolapse This deformity is seen in some of the tropical zebu breeds but is not uncommon in European breeds. Initially, it begins as a temperory eversion of a small p

Describe chemical equation of photosynthesis?, Q. What is the chemical equa...

Q. What is the chemical equation of photosynthesis? The chemical equation of photosynthesis is given below: 6 CO 2 + 6 H 2 O + light --> C 6 H 12 O 6 + 6 O 2

Describe what is circulatory support and inotropes, Describe what is Circul...

Describe what is Circulatory Support and Inotropes ? Colloid or Crystalloids: Hypotension after PGEl infusion is common. It is the result of relative intravascular volume deple

Is the bacterium mrsa pathogenic or non-pathogenic, Is the bacterium MRSA p...

Is the bacterium MRSA pathogenic or non-pathogenic? MRSA bacteria are pathogenic. This group of bacteria belongs to Staphylococcus aureus family, which have grown resistant to

Explain disease dengue, Dengue Dengue fever is a viral disease transmi...

Dengue Dengue fever is a viral disease transmitted by mosquito bites that occurs worldwide in tropical and subtropical areas. Major epidemics have occurred in recent years in

Show characteristics of protozoans, Q. What are the characteristics of prot...

Q. What are the characteristics of protozoans that make them resemble animals? Protozoans are unicellular beings with some related characteristics to animal cells. In compar

Active or moderately active lifestyles - physical activity, Define Active o...

Define Active or moderately active Lifestyles - physical activity? These people have occupations that p-e not strenuous in terms of energy demands, but involve more energy expe

Physical examination of a child, PHYSICAL EXAMINATION OF A CHILD This ...

PHYSICAL EXAMINATION OF A CHILD This practical as you have seen above deals with assisting in various diagnostic procedures of a child. The first responsibility of you as a

Explain the protein efficiency ratio (per), Explain the Protein Efficiency ...

Explain the Protein Efficiency Ratio (PER)? PER method was developed by Osborne, Mendel and Ferry in 1919 and is based on the growth of young rats. The diets usually contain 10

How molecular biology change forsenic biology, Explain in 100+ words Why/ho...

Explain in 100+ words Why/how did molecular biology change forsenic biology.

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd