Explain rifabutin, Biology

Assignment Help:

Explain Rifabutin

Two alternative regimens are based on the fact that rifabutin appears to be as effective as rifampin against TB, and has less effect on protease inhibitor levels. The first substitutes low-dose rifabutin (150 mg once/day or 300 mg 3x/week) for rifampin in the standard regimen (i.e., isoniazid, rifabutin, pyrazinamide and ethambutol) and uses higher than usual doses of indinavir (Crixivan) or nelfinavir (Viracept), or standard doses of amprenavir (Agenerase) or fos amprenavir (Lexiva)  as the protease inhibitor.

The second decreases the rifabutin dose further to 150 mg every other day or 3 times weekly and gives it with standard doses of atazanavir  (Reyataz), ritonavir/lopinavir (Kaletra) or ritonavir alone or combined with other protease inhibitors. Saquinavir (Fortovase, Invirase) alone should not be used. If the HAART regimen contains nevirapine, the usual dose of rifabutin should be used. Higher rifabutin doses (450-600 mg daily) are needed if the HAART regimen contains efavirenz.

 


Related Discussions:- Explain rifabutin

How phosphorus in blood is presented, How Phosphorus in Blood is presented?...

How Phosphorus in Blood is presented? Phosphorus in Blood is Present as: 1.  Inorganic phosphorus in the form of HPO 4 or H 2 PO 4 2.  Organic or ester phosphorus such

Explain beef extract and yeast extract, Explain Beef Extract and Yeast Extr...

Explain Beef Extract and Yeast Extract These are aqueous extracts of lean beef and brewer's yeast, respectively. Beef extract provides amino acids, peptides, nucleotides, organ

Sample titration for determination of iodine number of lipid, Define Sample...

Define Sample titration for Determination of the Iodine Number of Lipids? With a clean dry pipette, accurately measure 0.3 mL of oil into a clean and dry iodination flask (Dupl

Explain the uses of isp in seafood products, Explain the Uses of ISO in Sea...

Explain the Uses of ISO in Seafood products  Seafood products  The most significant application in this category is the use of ISP in fish sausage and surimi based restructu

What is diagnosis of heart disease in the newborn, What is Diagnosis of Hea...

What is Diagnosis of Heart Disease in the Newborn ? Clinical diagnosis of heart disease in the newborn can be quite challenging. Manifestations of potentially life threatening

Define behaviour modification - combat from obesity problem, Define Behavio...

Define Behaviour modification - combat from obesity Problem? It is very important. A heavy parental hand and parent attitude and behaviours towards child's eating, interferes i

Understanding behaviour of diabetic patients, Q. Understanding Behaviour of...

Q. Understanding Behaviour of diabetic patients? Beliefs  Each of us has a set of beliefs that were learned by us when we were young. These include religious beliefs and

Pericardiocentesis, Pericardiocentesis It is removal of fluid form the...

Pericardiocentesis It is removal of fluid form the pericardial sac. It is a specialized procedure done n ICU or cardiac cath lab or OT. A 16 or 18 gauge needle is inserted

Gas exchange, Gas Exchange Gill surface area must be large enough to p...

Gas Exchange Gill surface area must be large enough to provide adequate exchange of gases. Therefore, highly active fish have largest relative gill area. Figure compares highl

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd