Explain rifabutin, Biology

Assignment Help:

Explain Rifabutin

Two alternative regimens are based on the fact that rifabutin appears to be as effective as rifampin against TB, and has less effect on protease inhibitor levels. The first substitutes low-dose rifabutin (150 mg once/day or 300 mg 3x/week) for rifampin in the standard regimen (i.e., isoniazid, rifabutin, pyrazinamide and ethambutol) and uses higher than usual doses of indinavir (Crixivan) or nelfinavir (Viracept), or standard doses of amprenavir (Agenerase) or fos amprenavir (Lexiva)  as the protease inhibitor.

The second decreases the rifabutin dose further to 150 mg every other day or 3 times weekly and gives it with standard doses of atazanavir  (Reyataz), ritonavir/lopinavir (Kaletra) or ritonavir alone or combined with other protease inhibitors. Saquinavir (Fortovase, Invirase) alone should not be used. If the HAART regimen contains nevirapine, the usual dose of rifabutin should be used. Higher rifabutin doses (450-600 mg daily) are needed if the HAART regimen contains efavirenz.

 


Related Discussions:- Explain rifabutin

Define recommended dietary allowance for pyridoxine (rda), Define Recommend...

Define Recommended Dietary Allowance for pyridoxine (RDA)? Average requirements for pyridoxine vary with age, sex and physiological conditions such as protein status, pregnan

Explain hyperglycaemic, Hyperglycaemic:- In the fasting state, glucose ...

Hyperglycaemic:- In the fasting state, glucose release from the liver increases due to the action of glucagon and in the muscle by epinephrine. Glucagon  also  enhances glucone

Define the use of computers in numerical taxonomy, Define the Use of Comput...

Define the Use of Computers in Numerical Taxonomy The use of computers in numerical taxonomy has made it possible to compare a large number of characters from many organisms wi

Zoology, Give the salient features of phylum protozoa

Give the salient features of phylum protozoa

Explain carboxypeptidase, Carboxypeptidase The  inactive  zymogen  proc...

Carboxypeptidase The  inactive  zymogen  procarboxypeptidase  is  activated  by  trypsin .The further action on the polypeptides is carried out by carboxypeptidase which  attac

Explain some effect of inadequate nutrition, Explain some Effect of Inadequ...

Explain some Effect of Inadequate nutrition? Inadequate nutrition ranks as one of the major problems of old age. Various factors which may be responsible for the change in one

What is biochemical composition, What is Biochemical Composition As lif...

What is Biochemical Composition As life evolved on this planet, nature selected only a few elements, and life eventually came to be based essentially on carbon compounds. Out o

Define traditional methods of food processing, Define Traditional Methods o...

Define Traditional Methods of Food Processing? Because food is so important to survival and most foods remain edible for only a brief period of time, people as the initial ages

Planning of the nursing care, Planning of the Nursing Care 1) Educa...

Planning of the Nursing Care 1) Educate and teach the parents 2) Provide preoperative and postoperative care. Educate an Teach the Parents The parents may be

Sulphur (s) - macronutrients, Sulphur (S) - Macronutrients Sulphur is ...

Sulphur (S) - Macronutrients Sulphur is present in the soil in inorganic and organic forms. In most soils organically bounds is the major S reservoir. The inorganic forms of S

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd