Explain rifabutin, Biology

Assignment Help:

Explain Rifabutin

Two alternative regimens are based on the fact that rifabutin appears to be as effective as rifampin against TB, and has less effect on protease inhibitor levels. The first substitutes low-dose rifabutin (150 mg once/day or 300 mg 3x/week) for rifampin in the standard regimen (i.e., isoniazid, rifabutin, pyrazinamide and ethambutol) and uses higher than usual doses of indinavir (Crixivan) or nelfinavir (Viracept), or standard doses of amprenavir (Agenerase) or fos amprenavir (Lexiva)  as the protease inhibitor.

The second decreases the rifabutin dose further to 150 mg every other day or 3 times weekly and gives it with standard doses of atazanavir  (Reyataz), ritonavir/lopinavir (Kaletra) or ritonavir alone or combined with other protease inhibitors. Saquinavir (Fortovase, Invirase) alone should not be used. If the HAART regimen contains nevirapine, the usual dose of rifabutin should be used. Higher rifabutin doses (450-600 mg daily) are needed if the HAART regimen contains efavirenz.

 


Related Discussions:- Explain rifabutin

Carrier ions like na+ facilitate the absorption of substance, Carrier ions ...

Carrier ions like Na+ facilitate the absorption of substances like: 1. amino acids and glucose 2. glucose and fatty acids 3. fatty acids and glycerol 4. fructose and so

Metazoan branches, Metazoan Branches The Kingdom Animalia comprises al...

Metazoan Branches The Kingdom Animalia comprises all the multicellular animals (metazoans). These are divided into three branches: Mesozoa Parazoa Eumetazoa

What is intra oral and extra oral, What is Intra oral and Extra Oral A...

What is Intra oral and Extra Oral A) Intra oral a) Frontal in occlusion b) Left and right occlusion (Using intra oral photography mirror) c) Occlusal view maxillary

What is the function of the umbilical cord, What is the function of the umb...

What is the function of the umbilical cord? The umbilical cord is a set of blood vessels that connects the fetus with the placenta. In the fetus one extremity of the cord inse

What are the maximum crop yields, What are the Maximum Crop Yields   Mi...

What are the Maximum Crop Yields   Mitscherlich conducted a large number of experiments with different plants, making use of pots 20 cm in diameter and 20 cm in depth. By addin

Ecology.., write the charecteristics of lake ecosystem

write the charecteristics of lake ecosystem

Categorisation of neuropsychological assessment, Categorisation of Neuropsy...

Categorisation of Neuropsychological Assessment One can divide neuropsychological assessment into two areas: i) Comprehensive and ii) Specialised assessment. Comprehen

How many computers can access the ebook on, I usually study in the library ...

I usually study in the library on the schools computers so I will be accessing the eBook from many different computers throughout the semester. Is there a limit to how many compute

Structure of the vascular system, Structure of the Vascular System Th...

Structure of the Vascular System The layers of the vascular system are all similar in veins and ateries. The difference of thickness of various layers constitute the functio

What function present in placental mammalian embryos, Q. Which is the extra...

Q. Which is the extraembryonic membrane whose function is to store nitrogen wastes of the embryo? Is this function present in placental mammalian embryos? The allantois is the

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd