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Gene repressor proteins which inhibit the transcription of particular genes in eukaryotes also exist. They may act by binding either to control parts within the promoter region near the gene or at sites located a long distance away from the gene, called as silencers. The repressor protein should inhibit transcription directly. One instance is the mammalian thyroid hormone receptor that, in the absence of thyroid hormone represses transcription of the goal genes. Furthermore, other repressors inhibit transcription by blocking activation. This can be get in one of several ways: by blocking the DNA binding site for an activator protein, through binding to and masking the activation domain of the activator factor, or by forming a non-DNA binding complex with the activator protein. Several instance of every mode of action are known.
Cytokines activate inflammatory cells like neutrophils and eosnophils.IL-5 is important in activation of eosnophils, IL-4 enhances IgE production by B-cells. IL-4, Il-5, IL-6, TNF-
Tubercular Meningitis (TBM) Tubercular meningitis is a serious complication of childhood tuberculosis. It usually occurs secondarily to primary infection with tuburculosi
Anther Dehiscence and Pollen Transfer Anther Dehiscence Anther dehiscence simply means the release of pollen grains from dry and mature anthers. It involves the rupturi
Osmosis and transpiration both play a part in the movement of water through a plant. Which of these two processes makes the greater contribution to the movement of water up the t
Bleeding on Probing (BOP) BOP when elicited (notated in patient record as BOP +) after the insertion of a probe into the sulcus with light pressure i.e. 25 N has been shown to
Q. In ancient Greece the father of Medicine, Hypocrates, described a method of diagnosing diabetes mellitus by tasting the patient's urine. What is the physiological explanation fo
What is the name of enzyme in gastric juice?
Inhibitor Proteins - Enzyme-activity Control One kind of inhibitor protein found in higher plants is an endopeptidase which degrades nitrate reductase thus causing irreversibl
Sublimation is the process by which solid water changes directly to vapour phase without passing through the intervening liquid phase. The gradual disappearance of flakes of ice
is the leukamia dangerous
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