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Gene repressor proteins which inhibit the transcription of particular genes in eukaryotes also exist. They may act by binding either to control parts within the promoter region near the gene or at sites located a long distance away from the gene, called as silencers. The repressor protein should inhibit transcription directly. One instance is the mammalian thyroid hormone receptor that, in the absence of thyroid hormone represses transcription of the goal genes. Furthermore, other repressors inhibit transcription by blocking activation. This can be get in one of several ways: by blocking the DNA binding site for an activator protein, through binding to and masking the activation domain of the activator factor, or by forming a non-DNA binding complex with the activator protein. Several instance of every mode of action are known.
Q. Show Coding for stimulus intensity? Coding for stimulus intensity: If AP's are all-or-none responses that do not vary in amplitude, how does the NS distinguish between stim
Vasoactive substances such as Endothelium Derived Relaxing Factors (EDRF). Prostacyclin and Endothelin can be formed in the vascular endothelium. Endothelial dysfunction can lead t
Define Sodium, Potassium and Chloride - Minerals? Claude Bernard was the first to draw attention to the internal environment (milieu interior), referring to the extracellular f
Question 1 What is megalobastic anemia? Discuss briefly its lab diagnosis. How would you differentiate megaloblastic anemia from other anemias? Question 2 What is hemog
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how many grams of table sugar would you need to dissolved in water to produce 0.75 liters of a 0:25 molar acqeous solution of table sugar?
Calcium antagonists are not recommended for the treatment of CHF because of their negative inotropic effects. However, second-generation dihydropyridine-type calcium antagonists su
Removable soft tissue-borne partial dentures have one of the lowest patient acceptance rates in dentistry. Those patients wearing the partial dentures often exhibit greater mobilit
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