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Explain Prevalence in coronaw artery disease ?
The first report to highlight the high prevalence of CAD among Indian expatriates came from an autopsy study done in Singapore. Coronary artery disease with myocardial involvement was seven times more common in Indians when compared to Chinese males. Subsequently, other studies from Singapore, Uganda, South Africa and Fiji confirmed a three-fold higher prevalence of CAD in Indians compassed to the respective native populations. In the Southall Study, the prevalence of CAD diagnosed by the presence of major Q waves was four per cent in India born man compaired 2.3 per cent in Europeans. Physicians of Indian origin ('first generation Indians') who have migrated to the West have Sour times higher prevalence of CAD ( 1 0 per cent) than that of general physicial population in USA. The age-adjusted prevalence of myocardial infarction (MI) or angina was three times more in Indian men (mean age 46.4 years) compared to the men in the Framingham Offspring Study(7 .2 per cent vs. 2.5 per cent).
While South Asians exhibit the highest prevalence of CAD and coronary risk factors as compared with Caucasians, they even differ from the other Asians. CAD prevalence rates for them are six times higher than Chinese and four times higher than other Asian Americans. In contrast Japanese have the similar prevalence rates as Whites. More 1.ecent1y the study of Health Assessment and Risk in Ethnic groups (SHARE) from Canada showed that the overall prevalence of CAD was 10.7 per cent among South Asian Indians versus 4.6 per cent in Europeans and 1.7 per cent in Chinese population.
please give me the expansion for ''gradient hypothesis'' and the two types of gradient hypothesis in deelopment of animals in detailed manner
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