Explain non-nucleoside reverse transcriptase inhibitors, Biology

Assignment Help:

Non-nucleoside reverse transcriptase inhibitors

(NNRTIs) - These drugs are direct, non-nucleoside inhibitors of HIV-1 reverse transcriptase. Combinations of an NNRTI with NRTIs tend to be at least additive in reducing HIV replication in vitro. HIV isolates that are resistant to NRTIs and protease inhibitors remain sensitive to NNRTIs, but cross-resistance is common within the NNRTI class. Resistance to NNRTIs develops rapidly if they are used alone or in combinations that do not completely suppress viral replication.

 


Related Discussions:- Explain non-nucleoside reverse transcriptase inhibitors

Fundamental cardiac unit, The fundamental contractile unit is the sarcomere...

The fundamental contractile unit is the sarcomere. Each muscle cell apart from the nucleus, mitochondria and other structures contains parallel fibrils. Sarcomere is a subunit of t

Describe the use of sorbates acid in microorganisms, Q. Describe the use of...

Q. Describe the use of Sorbates acid in Microorganisms? Sorbic acid is an unsaturated carboxylic acid whose salts as sodium, calcium or potassium are used in foods upto

Kindom amimalia, charachteristicsof phylum canidaria

charachteristicsof phylum canidaria

Traumatic reticuloperitonitis (trp), Tr aumatic reticuloperitonitis (TRP) ...

Tr aumatic reticuloperitonitis (TRP) It is also known as traumatic gastritis, hardware disease or traumatic reticulitis. Et i o l o g y : Frequentl

Of which substance are microtubules made, Of which substance are microtubul...

Of which substance are microtubules made? In which structures and cellular processes do microtubules participate? Microtubules are made of consecutive dimers of the protein tub

Disorders of motor neurons and the spinal cord, Disorders of motor neurons ...

Disorders of motor neurons and the spinal cord A number of movement disorders are produced by damage either to the spinal cord or to cortical projections to the spinal cord. Th

Why to dilute this stock to give the desired concentration, You are working...

You are working on a protocol in lab that requires 10ml of a 5% saline solution for a particular step. All you have in your lab is a 20% saline stock solution. How can you dilute t

Characters of the hemichordata, Two typical characters of the Hemichordata ...

Two typical characters of the Hemichordata that can be observed and used to identify them are: i) Soft, worm-like or short unsegmented body. ii) Body is divided into a (i) pr

Major events during gastrulation, MAJOR EVENTS DURING GASTRULATION - 1....

MAJOR EVENTS DURING GASTRULATION - 1.       There is rearrangement of cells due to morphogenetic movement of the cells of blastoderm. 2.       The three primary germ layer g

What are risk factors for diseases, What are risk factors for diseases? ...

What are risk factors for diseases? Risk factors for a disease are everything that contributes to enhance the risk of the disease to appear. For instance, for most cardiovascul

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd