Explain non-nucleoside reverse transcriptase inhibitors, Biology

Assignment Help:

Non-nucleoside reverse transcriptase inhibitors

(NNRTIs) - These drugs are direct, non-nucleoside inhibitors of HIV-1 reverse transcriptase. Combinations of an NNRTI with NRTIs tend to be at least additive in reducing HIV replication in vitro. HIV isolates that are resistant to NRTIs and protease inhibitors remain sensitive to NNRTIs, but cross-resistance is common within the NNRTI class. Resistance to NNRTIs develops rapidly if they are used alone or in combinations that do not completely suppress viral replication.

 


Related Discussions:- Explain non-nucleoside reverse transcriptase inhibitors

Sodium - mineral elements, SODIUM The element is available in table sa...

SODIUM The element is available in table salt. A proper balance of sodium and potassium is essential. Its absorption is under control of aldasterone. The various f

What do you mean by zoological nomenclature, What do you mean by Zoological...

What do you mean by Zoological Nomenclature? This trust is housed in the British Museum, London and is responsible for some of the most important literature in Zoological Nomen

Show the model of behaviour change, Behavior Change Communication (BCC) int...

Behavior Change Communication (BCC) interventions that address diabetes mellitus are designed to promote behaviors that prevent diabetes and complications of diabetes. Behavior cha

What is the etiology of cholera, Q. What is the etiology of cholera? T...

Q. What is the etiology of cholera? The most common cause of cholera is consumption of food or drinking water that has been contaminated with the bacteria. It is important to

Discuss about intracellular perfusion fluid, At 1 AM, a healthy squid giant...

At 1 AM, a healthy squid giant axon is placed in a bath of normal squid physiological extracellular saline and is internally perfused with normal squid intracellular saline.  I

What is the usual reproduction cycle of a dna virus, Q What is the usual re...

Q What is the usual reproduction cycle of a DNA virus? A usual virus has proteins on its capsid that bind to the outer membrane of the host cell. In the place where the virus a

The upper or mountain course - classification of the river, The upper or mo...

The upper or mountain course - Classification of the river Here the water is fast flowing and runs through a 'V' shaped valley with unstable banks. The fast flowing water has

Signal transduction, Signal Transduction The body consists of a huge va...

Signal Transduction The body consists of a huge variety of cell types which must work together to sustain the life of an organism. They must respond to their environment and co

Explain the term trans fatty acids, Explain the term Trans fatty acids? ...

Explain the term Trans fatty acids? Plant derived fats and oils contain cis-fatty acids. You may recall reading about the cis and trans isomers in the Nutritional Biochemistry

Determine the term - akinetic and myoclonic seizures, Determine the term - ...

Determine the term - Akinetic and Myoclonic Seizures Akinetic seizures are ordinarily seen only in children. Usually, an affected child collapses suddenly and without warning.

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd