Explain nephrotoxicity, Biology

Assignment Help:

Explain Nephrotoxicity

Nephrotoxicity is the major dose-limiting toxicity of amphotericin B deoxycholate; sodium loading with  normal saline may prevent or ameliorate it and is generally recommended for patients who can tolerate a fluid load. The nephrotoxicity of amphotericin B may add to the nephrotoxicity of other drugs including cyclosporine (Sandimmune, Neoral), tacrolimus  (Prograf)  and aminoglycoside antibiotics like gentamicin (Garamycin, and others). Hypo- kalemia and hypomagnesemia are common and are usually due to a mild renal tubular acidosis. Weight loss, malaise, anemia, thrombocytopenia and mild leukopenia can happen. Cardiac toxicity and myopathy have been reported.

 


Related Discussions:- Explain nephrotoxicity

Which terrestrial vertebrate group is extremely rare deserts, Which terrest...

Which terrestrial vertebrate group is extremely rare in deserts? The Amphibians are terrestrial vertebrates very rare in desert environments (although there are a few species a

Explain food applications of dextran, Food Applications Dextran can be ...

Food Applications Dextran can be used in food products, as it is capable of moisture retention and inhibition of crystallization of sugar. The properties of dextran as gelling

Define role of nutrients in controlling gene expression, Define Role of Nut...

Define Role of Nutrients in Controlling Gene Expression? The role of several nutrients in controlling gene expression, as mentioned earlier, is in infancy, but with advancing b

Palaeontological evidence of evolution, EVIDENCES OF EVOLUTION - The ev...

EVIDENCES OF EVOLUTION - The evidences of organic evolution derived from many lines of study indicate that present day forms have arisen by gradual changes from pre existing fo

Plant tissue, classification of plan''s tissue

classification of plan''s tissue

Explain briefly nucleic acids dna and rna, Explain briefly Nucleic Acids (D...

Explain briefly Nucleic Acids (DNA & RNA)? Nucleic Acids (DNA & RNA) :  Nucleic acids are the molecules that contain genetic information that is inherited, and are responsibl

Role of hormones in aging, Role of Hormones in Aging Aging as well ref...

Role of Hormones in Aging Aging as well reflects the inefficiency of the endocrine system. A change in the hormonal secretions may contribute to the development of physical ai

Endosperm with micropylar haustorium, Endosperm with micropylar Haustorium ...

Endosperm with micropylar Haustorium A very prominent and aggressive micropylar haustorium is seen in Impatiens. Here the division of the primary endosperm nucleus is followed

Determine what is dermal branchiae, Determine what is dermal branchiae? ...

Determine what is dermal branchiae? External extensions of outer epidermis and peritoneum of the echinoderm body cavity. Both outer epidermis and inner peritoneum are lined wit

Determine food sources for zinc, Determine Food Sources of Zinc? Zinc i...

Determine Food Sources of Zinc? Zinc is normally associated with the protein and/or nucleic acid fraction of foods. Thus, foods high in proteins are good sources of zinc. Lean

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd