Already have an account? Get multiple benefits of using own account!
Login in your account..!
Remember me
Don't have an account? Create your account in less than a minutes,
Forgot password? how can I recover my password now!
Enter right registered email to receive password!
Explain Major Histocornpatability Complex (MHC)
Major histocompatability complex is also known as the Human Leukocyte Antigen (HLA). MHC molecules are important components of the immune response. They permit cells that have been invaded by an infectious organism to be detected by the cells of the immune system called T-lymphocytes or T-cells. The MHC molecules do this by offering fragments of proteins (peptides) belonging to the invader on the surface of the cell. The T-cell recognizes the foreign peptide attached to the MHC molecule and binds to it, an action which stimulates the T-cell to either destroy or cure the infected cell. The MHC, therefore, is a set of genes that code for cell surface glycoproteins. These glycoproteins mark the body cells as 'self' and are divided into two main classes - class I MHC molecules are found on the surface of almost every cell of the body.
Class ll MHC molecules are confined to a few specialized cell types, such as macrophages, B-cells and activated T-cells. Each MHC antigen combination forms a unique complex that is recognized by specific antigen receptors on T-cells as 'self'. T-cell surface proteins CD4 and CD8 greatly enhance the interaction between an antigen presenting cell (APC) and killer T-cell and between AF'C and helper T-cell, respectively. The primary immunological function of MHC molecules, therefore, is to bind and "present" antigenic peptides on the surfaces of cells for recognition (binding) by the antigen- specific T-cell receptors (TCRs) of lymphocytes. The other specific defence mechanism in our body is the antibodies. Let us learn about their role in the immune system and their interaction with antigens.
Ask question how many years that our earth survived?#Minimum 100 words accepted#
Effects of Global warming ñ Alterations in the Global Precipitation: A more warm atmosphere will contribute to enhanced evaporation from surface waters and leads to the more
How soil textural classes categorised and what are is their significance? The soil textural classes are based on the percentage of the separate(s) which contributes maximum to
Explain Betice Jones Protein - abnormal constituent of urine Betice-Jones Protein: Bence-Jones proteins are the small proteins (dimers of iminunoglobuljn light chains) normally
Q. Write the purposes of conditioning of wheat prior to milling? The purpose of conditioning of wheat prior to milling are to make the bran and germ pliable, thus preventing th
what properties identify nonmetals
Soil Textural Classes On the basis of the proportion of different soil separates present, the soils are classified into different groups called as soil classes. The soil class
How did the Earth form and become spherical? The Earth's Shape : About five billion years ago the solar system was forming from gases and dust floating in space. Gravity, th
Explain Protective and Excretory Function Protective function: Large quantity of mucin is secreted by gastric glands. Mucin lubricates the food bolus (a mass of chewed food) an
Define Hypoparathyroidism Hypoparathyroidism or a decrease in the secretion of parathormone causes an upset in calcium metabolism. Hypocalcemia develops and the muscles go into
Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!
whatsapp: +91-977-207-8620
Phone: +91-977-207-8620
Email: [email protected]
All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd