Already have an account? Get multiple benefits of using own account!
Login in your account..!
Remember me
Don't have an account? Create your account in less than a minutes,
Forgot password? how can I recover my password now!
Enter right registered email to receive password!
Explain Major Histocornpatability Complex (MHC)
Major histocompatability complex is also known as the Human Leukocyte Antigen (HLA). MHC molecules are important components of the immune response. They permit cells that have been invaded by an infectious organism to be detected by the cells of the immune system called T-lymphocytes or T-cells. The MHC molecules do this by offering fragments of proteins (peptides) belonging to the invader on the surface of the cell. The T-cell recognizes the foreign peptide attached to the MHC molecule and binds to it, an action which stimulates the T-cell to either destroy or cure the infected cell. The MHC, therefore, is a set of genes that code for cell surface glycoproteins. These glycoproteins mark the body cells as 'self' and are divided into two main classes - class I MHC molecules are found on the surface of almost every cell of the body.
Class ll MHC molecules are confined to a few specialized cell types, such as macrophages, B-cells and activated T-cells. Each MHC antigen combination forms a unique complex that is recognized by specific antigen receptors on T-cells as 'self'. T-cell surface proteins CD4 and CD8 greatly enhance the interaction between an antigen presenting cell (APC) and killer T-cell and between AF'C and helper T-cell, respectively. The primary immunological function of MHC molecules, therefore, is to bind and "present" antigenic peptides on the surfaces of cells for recognition (binding) by the antigen- specific T-cell receptors (TCRs) of lymphocytes. The other specific defence mechanism in our body is the antibodies. Let us learn about their role in the immune system and their interaction with antigens.
General appearance - General Examination of Urine Dilute urine is usually pale and straw-colored while the concentrated urine is dark and acid urine is darker. Blood may cause
what makes a mineral a mineral? The properties of minerals: There are seven main properties that are used to describe and classify any mineral found. All seven properties are
Define the Nature of Sound This section is a recapitulation of what you have learnt in school. You would recall that sound waves consist of the longitudinal waves of alternate
Explain Steroids Steroids form a group of compounds which are often found in association with fats but structurally and functionally these are somewhat unrelated to most
Mr. X was administered the Wechsler Adult Intelligence Scale-Fourth Edition (WAIS-IV), which is an individually administered test of a person's intellectual ability and cognitive s
Pulse products: The important processed pulse products are puffed chickpea and pea, besan, papads, pulse-based weaning foods, quick cooking dhals, and canned dry peas Oils
Explain Antibodies Antibodies (also referred to as immunoglobulins and garnmaglobulins) are produced by plasma cells. They are Y-shaped proteins that each respond to a specific
Model water wheels A meat skewer or a knitting needle can be used as an axle. An old typewriter ribbon- spool or a sticking plaster reel is useful as a basis for these improvis
1. Beta catenin is a protein that translocates to the nucleus in the presence of Wnt ligand. In the absence of Wnt, beta catenin is targeted for degradation. Using a cell line fro
Explain Age Related Changes - Ageing Age related changes are mainly observed at a cellular level. The connective tissues throughout body show an increase in stiffness because o
Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!
whatsapp: +91-977-207-8620
Phone: +91-977-207-8620
Email: [email protected]
All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd