Already have an account? Get multiple benefits of using own account!
Login in your account..!
Remember me
Don't have an account? Create your account in less than a minutes,
Forgot password? how can I recover my password now!
Enter right registered email to receive password!
Explain Major Histocornpatability Complex (MHC)
Major histocompatability complex is also known as the Human Leukocyte Antigen (HLA). MHC molecules are important components of the immune response. They permit cells that have been invaded by an infectious organism to be detected by the cells of the immune system called T-lymphocytes or T-cells. The MHC molecules do this by offering fragments of proteins (peptides) belonging to the invader on the surface of the cell. The T-cell recognizes the foreign peptide attached to the MHC molecule and binds to it, an action which stimulates the T-cell to either destroy or cure the infected cell. The MHC, therefore, is a set of genes that code for cell surface glycoproteins. These glycoproteins mark the body cells as 'self' and are divided into two main classes - class I MHC molecules are found on the surface of almost every cell of the body.
Class ll MHC molecules are confined to a few specialized cell types, such as macrophages, B-cells and activated T-cells. Each MHC antigen combination forms a unique complex that is recognized by specific antigen receptors on T-cells as 'self'. T-cell surface proteins CD4 and CD8 greatly enhance the interaction between an antigen presenting cell (APC) and killer T-cell and between AF'C and helper T-cell, respectively. The primary immunological function of MHC molecules, therefore, is to bind and "present" antigenic peptides on the surfaces of cells for recognition (binding) by the antigen- specific T-cell receptors (TCRs) of lymphocytes. The other specific defence mechanism in our body is the antibodies. Let us learn about their role in the immune system and their interaction with antigens.
Explain Control of Our Heart through Nerves When we exercise in the mornings, the heart beats faster and when we sleep at night, it slows down. Have you ever wondered how does
Explain the Respiratory Centre The respiratory centre consists of two main parts - inspiratory centre and the expiratory centre. The inspiratory centre is dominant. A reciproca
Explain the Simple Cells - Primary Visual Cortex They are most sensitive to lines oriented in a particular angle to the vertical. Simple cells probably receive a convergence of
Why Rainfall is imprtant factor in active soil formation Of the various climatic elements that take part in active soil formation, rainfall or precipitation is the most importa
Handling of Chemicals : Laboratory technicians who work in laboratories, need to be aware of the potential danger of the substances they handle. In the case of those working in ch
If the Quabbin Reservoir Watershed is 100 km2, the average precipitation in New England is 130 cm/year, and the volume of the reservoir is 1.5 x 1012 liters, what is the residence
how do i make a box being pulled up a rough incline by a rope connected to a pulley
Interaction in the earth ecosystem: In this comparatively smaller section, we will give you the idea, that the earth as a whole is an ecosystem. Whatever you have learnt till
Ecological Crises: The natural atmosphere which man has inherited from the past, with healthy and fresh air, shielding from excessive radiation of the sun, has been deteriorat
Night Sky: When you look up at the sky on a clear night, what do you-see? Most of it is dotted with twinkling stars. You may see the moon or Venus as a bright point or Mars as
Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!
whatsapp: +1-415-670-9521
Phone: +1-415-670-9521
Email: [email protected]
All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd