Already have an account? Get multiple benefits of using own account!
Login in your account..!
Remember me
Don't have an account? Create your account in less than a minutes,
Forgot password? how can I recover my password now!
Enter right registered email to receive password!
Explain Major Histocornpatability Complex (MHC)
Major histocompatability complex is also known as the Human Leukocyte Antigen (HLA). MHC molecules are important components of the immune response. They permit cells that have been invaded by an infectious organism to be detected by the cells of the immune system called T-lymphocytes or T-cells. The MHC molecules do this by offering fragments of proteins (peptides) belonging to the invader on the surface of the cell. The T-cell recognizes the foreign peptide attached to the MHC molecule and binds to it, an action which stimulates the T-cell to either destroy or cure the infected cell. The MHC, therefore, is a set of genes that code for cell surface glycoproteins. These glycoproteins mark the body cells as 'self' and are divided into two main classes - class I MHC molecules are found on the surface of almost every cell of the body.
Class ll MHC molecules are confined to a few specialized cell types, such as macrophages, B-cells and activated T-cells. Each MHC antigen combination forms a unique complex that is recognized by specific antigen receptors on T-cells as 'self'. T-cell surface proteins CD4 and CD8 greatly enhance the interaction between an antigen presenting cell (APC) and killer T-cell and between AF'C and helper T-cell, respectively. The primary immunological function of MHC molecules, therefore, is to bind and "present" antigenic peptides on the surfaces of cells for recognition (binding) by the antigen- specific T-cell receptors (TCRs) of lymphocytes. The other specific defence mechanism in our body is the antibodies. Let us learn about their role in the immune system and their interaction with antigens.
i need help
What is your evaluation of the effectiveness of the U.S. health care system in the context of delivery, finance, management, and/or sustainability? What are the issues that prompte
Ask question #Minimum 100 words acceptedYou are caring for a 29-year-old woman who is married with two small children, ages 1 and 3 years, at home. She is recuperating from a left
describe the factors which decide broad area of scientific activity
Reflexes: It is of interest to know, that all sensory information does not have to go to the - brain before we can react to a stimulus. Our responses to certain stimuli
Define the functions of the Macrophages The macrophages: 1) phagocytose microorganisms and inert particles 2) secrete IL-1 (Interlukin I), TNF (tumor necrosis factor),
Explain Cough reflex Actions - Respiratory Process Cough reflex causes cough due to irritation of some receptors in tracheo-bronchial tree. It is a protective reflex. The irrit
1. Describe the paths of water through the hydrologic cycle. Explain the processes and the energy gains and losses involved in the changes of water between its 3 states. Operatio
Illustrate about the colour of the soil The colour of the soil gets influenced by the oxidation states of metal ions. Colours such as red, yellow and reddish brown are found u
Explain Ester formation Ester formation : In presence of dry HCl, amino acids react with alcohol to form esters. This is one of the ways of blocking XOOH group in the
Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!
whatsapp: +91-977-207-8620
Phone: +91-977-207-8620
Email: [email protected]
All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd