Already have an account? Get multiple benefits of using own account!
Login in your account..!
Remember me
Don't have an account? Create your account in less than a minutes,
Forgot password? how can I recover my password now!
Enter right registered email to receive password!
Explain Major Histocornpatability Complex (MHC)
Major histocompatability complex is also known as the Human Leukocyte Antigen (HLA). MHC molecules are important components of the immune response. They permit cells that have been invaded by an infectious organism to be detected by the cells of the immune system called T-lymphocytes or T-cells. The MHC molecules do this by offering fragments of proteins (peptides) belonging to the invader on the surface of the cell. The T-cell recognizes the foreign peptide attached to the MHC molecule and binds to it, an action which stimulates the T-cell to either destroy or cure the infected cell. The MHC, therefore, is a set of genes that code for cell surface glycoproteins. These glycoproteins mark the body cells as 'self' and are divided into two main classes - class I MHC molecules are found on the surface of almost every cell of the body.
Class ll MHC molecules are confined to a few specialized cell types, such as macrophages, B-cells and activated T-cells. Each MHC antigen combination forms a unique complex that is recognized by specific antigen receptors on T-cells as 'self'. T-cell surface proteins CD4 and CD8 greatly enhance the interaction between an antigen presenting cell (APC) and killer T-cell and between AF'C and helper T-cell, respectively. The primary immunological function of MHC molecules, therefore, is to bind and "present" antigenic peptides on the surfaces of cells for recognition (binding) by the antigen- specific T-cell receptors (TCRs) of lymphocytes. The other specific defence mechanism in our body is the antibodies. Let us learn about their role in the immune system and their interaction with antigens.
Explain the texture of igneous rocks? There are four main textures of igneous rocks which are used to classify them. The rate of cooling and crystal growth account for the diff
Explain Free-radical theory of Ageing The body is subjected to a dilemma. On one hand, O 2 is essential for life and on the other hand, oxidative reactions can set free a lot
Vitamin E (Tocopherols) Vitamin E is an essential fat-soluble vitamin that functions, at least in part, as a lipid- soluble antioxidant. Presence of vitamin E was first revea
what is benzoin condensation and what are the results of it and the uses of this reaction
Nonionising Radiations : As stated earlier the radiation hazards are not limited to ionising radiations from radioactive materials. There are a number of other radiation sources i
what is subphylum chordata?
Minerals and vltamins Minerals and vltamins are not a source of energy but they are necessary in many of the steps involved in the release of energy in the cells. Thus, t
A 57 year olf female presented to her GP with a history of fatigue, weight loss and incresingly severe back pain. on examination she appeared pale with no signs of hepatomegaly or
To measure the volume of air in the longs Invert a bottle full of water so that its neck is in the surface of water in ajar. Introduce a glass or rubber tube into the neck and
Precautions : The following precautions should be taken while using UV lamps: 1) TJV lamps must always be properly shielded. 2)Wear approved goggles when working with or clo
Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!
whatsapp: +91-977-207-8620
Phone: +91-977-207-8620
Email: [email protected]
All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd