Already have an account? Get multiple benefits of using own account!
Login in your account..!
Remember me
Don't have an account? Create your account in less than a minutes,
Forgot password? how can I recover my password now!
Enter right registered email to receive password!
Explain Major Histocornpatability Complex (MHC)
Major histocompatability complex is also known as the Human Leukocyte Antigen (HLA). MHC molecules are important components of the immune response. They permit cells that have been invaded by an infectious organism to be detected by the cells of the immune system called T-lymphocytes or T-cells. The MHC molecules do this by offering fragments of proteins (peptides) belonging to the invader on the surface of the cell. The T-cell recognizes the foreign peptide attached to the MHC molecule and binds to it, an action which stimulates the T-cell to either destroy or cure the infected cell. The MHC, therefore, is a set of genes that code for cell surface glycoproteins. These glycoproteins mark the body cells as 'self' and are divided into two main classes - class I MHC molecules are found on the surface of almost every cell of the body.
Class ll MHC molecules are confined to a few specialized cell types, such as macrophages, B-cells and activated T-cells. Each MHC antigen combination forms a unique complex that is recognized by specific antigen receptors on T-cells as 'self'. T-cell surface proteins CD4 and CD8 greatly enhance the interaction between an antigen presenting cell (APC) and killer T-cell and between AF'C and helper T-cell, respectively. The primary immunological function of MHC molecules, therefore, is to bind and "present" antigenic peptides on the surfaces of cells for recognition (binding) by the antigen- specific T-cell receptors (TCRs) of lymphocytes. The other specific defence mechanism in our body is the antibodies. Let us learn about their role in the immune system and their interaction with antigens.
EXTINGUISHING A FIRE : The techniques and equipment which you will learn about in this section relate to the standard kinds of fire fighting equipment found in buildings open to t
1. DH is admitted with end-stage liver disease and severe ascites requiring paracentesis while in the hospital. He has been started on PN therapy for his poor nutritiona
Fire Escapes : When a fire breaks out in a building, it is not unusual for people to panic. Sometimes flames can spread rapidly, especially if fanned by blow of air from open or b
Explain the texture of igneous rocks? There are four main textures of igneous rocks which are used to classify them. The rate of cooling and crystal growth account for the diff
Explain Protein Reserve - Functions of Plasma Proteins Plasma proteins provide a reserve, which can be drawn upon for vital functions in the situations of starvation and protei
STERILIZATION OF GLASSWARE Activity is related activities. Whenever you require the glassware for doing an experiment you can follow the procedure given in Activity independent
Normal 0 false false false EN-US X-NONE X-NONE MicrosoftInternetExplorer4
define carbohydrates.give a brief account on classification of carbohydrates.
How does nuclear power relate to kinematics?
Structure of the brain. Include different parts and their function.
Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!
whatsapp: +91-977-207-8620
Phone: +91-977-207-8620
Email: [email protected]
All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd