Explain lock and key model, Biology

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Fischer 's template or lock and key model

According to this model, the catalytic site of the enzyme has a proper conformation compatible to a specific substrate even  in  the absence of the substrate molecule. The catalytic site binds the substrate and catalyzes the reaction without any  change  in  its  own  three  dimensional conformation. It  has become possible to explain the specificity of many enzymes for only one of the stereoisomers of the  substrate by  this model.

 


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