Explain lipoprotein excess, Biology

Assignment Help:

Explain Lipoprotein (Lp(a) Excess ?

While cholesterol and triglycerides are important lipid risk factors, another lipoprotein factor called Lipoprotein (a) is thought to play a significant role especially in genetic predisposition to coronary artery disease. Lp (a) is a sub fraction of LDL but ten times more atherogenic, and its serum level is genetically determined. Being a dual pathogen influencing both atherosclerotic and thrombotic process, it is considered as a powerful independent risk factor for premature and extensive coronary disease. It is widely believed to be a biological marker for familial CAD, having the same significance as that of a history of premature CAD in the family.

The inherited serum levels of Lp(a) are not influenced by gender, diet, smoking, or other risk factors. The pathological effects of Lp (a) begin at a level of 20-30 mg/dl and are magnified in the presence of high LDL, low HDL or a high TCHDLc ratio, again highlighting the significance of lipid fraction interrelationship. There is a ethnic and genetic variability in the level of Lp(a). Indians have a higher level than other groups or races like Chinese or Japanese.

However there are no data showing that the decrease in Lp(a) levels is associated with a decrease in the incidence of Cardio-vascular or cerebro-vascular disease. The value of the routine screening for, and/or treating Lp(a) excess, is therefore still debatable. Even then Lp(a) levels should probably be taken into account impatient with CAD without established risk factors. The other factors should be rigorously modified or eliminated because, as has been seen, in hypercholesterolemia patients with increased Lp(a) levels, the decrease in LDL cholesterol levels is followed by neutralisation of the atherogenic potential of Lp(a).

 


Related Discussions:- Explain lipoprotein excess

Determine teenager mindset and the eating disorders, Determine Teenager min...

Determine Teenager mindset and the eating disorders? Self image is an important determinant of weight and figure. Mostly girls under eat as already mentioned earlier, in order

What is speciation, What is speciation? The Speciation is the process b...

What is speciation? The Speciation is the process by which different species emerge from a common ancestor species. The Speciation generally begins when populations of the same

State in brief about the zinc, State in brief about the Zinc    It is c...

State in brief about the Zinc    It is concerned with the functioning of sulphydryl compounds, such as cysteine, in regulation of redox potential within the cell. Zinc is somet

Relevance of biology to agriculture, ways in which modern agricultural acti...

ways in which modern agricultural activities may threaten survival species

Explain about rheology of foods, Q. Explain about Rheology of Foods? Rh...

Q. Explain about Rheology of Foods? Rheology is the study of stress and strain or in other words, it is the study of flow and deformation of materials, both liquids and solids,

Ground water sources and characteristics, After glaciers, ice caps and snow...

After glaciers, ice caps and snowfields, ground water is the next largest fresh water reservoir. Precipitation that does not evaporate back into the air and does not run off over t

What is the reduction of stress on the implant, Reduction of stress on the ...

Reduction of stress on the implant - Removal of prosthesis when it is in the non aesthetic areas - Occlusal adjustment - Reducing Cantilever length - Occlusal splint

Cold hardiness and cold acclimation, Cold Hardiness and Cold Acclimation ...

Cold Hardiness and Cold Acclimation In connection with cold response we would like to introduce two terms- cold hardiness and cold acclimation. Cold-hardiness ref

What are the physio-chemical properties of vitreous, What are the physio-ch...

What are the physio-chemical properties of vitreous? PHYSIO-CHEMICAL PROPERTIES OF VITREOUS: Vitreous is a clear gel like optically empty structure. Its physio-chemical prop

Lungs - respiratory organs, Lungs - Respiratory Organs In arachnid art...

Lungs - Respiratory Organs In arachnid arthropods such as scorpion and spider, respiration takes place by means of book lungs. There are four pairs of these structures in the

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd