Explain lipoprotein excess, Biology

Assignment Help:

Explain Lipoprotein (Lp(a) Excess ?

While cholesterol and triglycerides are important lipid risk factors, another lipoprotein factor called Lipoprotein (a) is thought to play a significant role especially in genetic predisposition to coronary artery disease. Lp (a) is a sub fraction of LDL but ten times more atherogenic, and its serum level is genetically determined. Being a dual pathogen influencing both atherosclerotic and thrombotic process, it is considered as a powerful independent risk factor for premature and extensive coronary disease. It is widely believed to be a biological marker for familial CAD, having the same significance as that of a history of premature CAD in the family.

The inherited serum levels of Lp(a) are not influenced by gender, diet, smoking, or other risk factors. The pathological effects of Lp (a) begin at a level of 20-30 mg/dl and are magnified in the presence of high LDL, low HDL or a high TCHDLc ratio, again highlighting the significance of lipid fraction interrelationship. There is a ethnic and genetic variability in the level of Lp(a). Indians have a higher level than other groups or races like Chinese or Japanese.

However there are no data showing that the decrease in Lp(a) levels is associated with a decrease in the incidence of Cardio-vascular or cerebro-vascular disease. The value of the routine screening for, and/or treating Lp(a) excess, is therefore still debatable. Even then Lp(a) levels should probably be taken into account impatient with CAD without established risk factors. The other factors should be rigorously modified or eliminated because, as has been seen, in hypercholesterolemia patients with increased Lp(a) levels, the decrease in LDL cholesterol levels is followed by neutralisation of the atherogenic potential of Lp(a).

 


Related Discussions:- Explain lipoprotein excess

Explain the features of alternaria, Explain the Features of Alternaria? ...

Explain the Features of Alternaria? 1. Alternaria colony is wooly and compact. Underside is very dark coloured. Colony colour is grayish green or black with gray edges rapidly

Define about the resistant starch, Define about the Resistant Starch? U...

Define about the Resistant Starch? Until 1980's starch was thought to be completely hydrolyzed and absorbed from the small intestine of man, independent of its source, type and

Lateral and the apical buds of the plants, What is the dissimilarity betwee...

What is the dissimilarity between the lateral and the apical buds of the plants? The Lateral buds are portions of meristematic tissue located in the base of the shoots. The Api

Explain ventilation, Explain Ventilation, Chest Compressions? Even when...

Explain Ventilation, Chest Compressions? Even when the first three defibrillation attempts fail, the best chance of resuscitation still lies in successful defibrillation. Hence

Which chemical causes tooth destruction, The bacteria that cause dental cav...

The bacteria that cause dental cavities in humans break down sugars, releasing what chemical which causes tooth destruction? a) Acids b) Bases c) Enzymes d) Monosaccha

Define treatment and management of adverse food reactions, Define Treatment...

Define Treatment and Management of Adverse Food Reactions? Management of adverse food reactions involves diagnosing the problem followed by nutritional and medical care.

Define the role of protein and purines, Q. Define the Role of Protein and P...

Q. Define the Role of Protein and Purines? Cellular materials of plants, grams and legumes and animal glandular organ meats (liver, pancreas brain, kidneys) contain nucleoprote

Noise pollution, Sound is a main mean of communication and entertainment an...

Sound is a main mean of communication and entertainment and is also very effective alarm system for some animal. A loud and unwanted or unpleasant sound causes discomfort and is ca

Logical order in which molecules-atoms are associated, Q What is the logica...

Q What is the logical order in which the concepts of molecules, atoms, cells... up to biosphere are associated? Atoms form molecules that form cells that form tissues that form

Which disease is associated with rapid dehydration, Which disease is associ...

Which disease is associated with the following symptoms? Sudden onset of profuse watery stool followed by vomiting, rapid dehydration and muscular cramps?

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd