Explain lipoprotein excess, Biology

Assignment Help:

Explain Lipoprotein (Lp(a) Excess ?

While cholesterol and triglycerides are important lipid risk factors, another lipoprotein factor called Lipoprotein (a) is thought to play a significant role especially in genetic predisposition to coronary artery disease. Lp (a) is a sub fraction of LDL but ten times more atherogenic, and its serum level is genetically determined. Being a dual pathogen influencing both atherosclerotic and thrombotic process, it is considered as a powerful independent risk factor for premature and extensive coronary disease. It is widely believed to be a biological marker for familial CAD, having the same significance as that of a history of premature CAD in the family.

The inherited serum levels of Lp(a) are not influenced by gender, diet, smoking, or other risk factors. The pathological effects of Lp (a) begin at a level of 20-30 mg/dl and are magnified in the presence of high LDL, low HDL or a high TCHDLc ratio, again highlighting the significance of lipid fraction interrelationship. There is a ethnic and genetic variability in the level of Lp(a). Indians have a higher level than other groups or races like Chinese or Japanese.

However there are no data showing that the decrease in Lp(a) levels is associated with a decrease in the incidence of Cardio-vascular or cerebro-vascular disease. The value of the routine screening for, and/or treating Lp(a) excess, is therefore still debatable. Even then Lp(a) levels should probably be taken into account impatient with CAD without established risk factors. The other factors should be rigorously modified or eliminated because, as has been seen, in hypercholesterolemia patients with increased Lp(a) levels, the decrease in LDL cholesterol levels is followed by neutralisation of the atherogenic potential of Lp(a).

 


Related Discussions:- Explain lipoprotein excess

Adverse effects of noise pollution, 1.      Effect on general health:  ...

1.      Effect on general health:          Noise pollution increases the rate of heart beat, constriction of blood vessels and blood pressure. Noise also causes anxiety, stres

fat digestion requires two steps, Fat digestion requires two steps? What a...

Fat digestion requires two steps? What are the steps and what enzymes are used to accomplish each step?

Osmosis: Hypertonic Solution, If a cell were placed in a hypertonic solutio...

If a cell were placed in a hypertonic solution what could it do to protect itself?

Explain doxycycline, Explain Doxycycline Doxycycline, which frequently c...

Explain Doxycycline Doxycycline, which frequently causes gastrointestinal disturbances and can cause photosensitivity and vaginitis, offers an inexpensive once-daily alternative

Simple closed circulation and double closed circulation, Q. What is the dif...

Q. What is the difference between simple closed circulation and double closed circulation? Double closed circulation or Closed circulation is that in which the blood circulates

Asexual reproduction in fungi, Asexual reproduction in fungi Fungi repr...

Asexual reproduction in fungi Fungi reproduce asexually by means of sporulation and fragmentation. Fragmentation : This is a type of asexual reproduction in fungi whi

Water supply, A rural town in an established agricultural area with no pros...

A rural town in an established agricultural area with no prospects for extensive development is located along a river that is used as the source of water supply for the community.

Discuss the biological importance of imidazole, Discuss the biological impo...

Discuss the biological importance of Imidazole. Bring in examples of biomolecules that contain this group. Please be as thorough as possible.

What are the main constituents of the earth atmosphere, What are the main c...

What are the main constituents of the earth's atmosphere in our time? The present atmosphere of the earth is constituted mostly of molecular nitrogen (N2) and molecular oxygen

Fruits, how to do write the assaigment in botany give idea

how to do write the assaigment in botany give idea

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd