Explain lipid formulations, Biology

Assignment Help:

Explain Lipid Formulations

Three lipid formulations of amphotericin B are marketed in the US: amphotericin B lipid complex (ABLC, Abelcet), liposomal amphotericin B (L-AmB, AmBisome), and amphotericin B colloidal dispersion (ABCD, Amphotec). In clinical trials, these formulations have been at least as effective as amphotericin B deoxycholate.

Compared to conventional amphotericin B, acute infusion-related reactions are worse with Amphotec, less with  Abelcet, and least with AmBisome.  Nephrotoxicity is less common with lipid-based products and, when it occurs, less severe than with amphotericin B deoxycholate. Liver toxicity, which is generally not associated with amphotericin B deoxycholate, has been reported with the lipid formulations

 


Related Discussions:- Explain lipid formulations

Lower respiratory tract, Lower Respiratory Tract: Trachea:   ...

Lower Respiratory Tract: Trachea:   Trachea or windpipe  is 12 cm long, 2.5 cm in diameter lying in front of the esophagus and  ends opposite the fourth dorsal

State about the latent squint disease, State about the Latent squint diseas...

State about the Latent squint disease Latent squint is seen commonly as exophoria in infancy and presbyopic age and esophoria in childhood. Hypermetropes can have esophoria and

Post-mating isolating mechanisms, The second category of isolating mechanis...

The second category of isolating mechanism that may permit interspecific mating but ensures reduced viability is called post-mating isolating mechanism. This category could be subd

What is digital periapical radiography, Q. What is Digital periapical radio...

Q. What is Digital periapical radiography? Digital radiographs can be subjected to image processing with which the images can be altered to achieve task specific image characte

Explain the communication process, Q. Explain the communication process? ...

Q. Explain the communication process? Communication is a process by which information is exchanged between individuals through a common system of symbols, signs, or behavior. C

Explain concept of digestion of proteins, Digestion of Proteins The pr...

Digestion of Proteins The proteolytic enzymes secreted  by  gastric juice, pancreatic juice  and  intestinal juice cause the hydrolysis of proteins in  the gastrointestinal tra

Ventricular septal defect, A newborn baby with a patent foramen ovale or a ...

A newborn baby with a patent foramen ovale or a ventricular septal defect might be cyanotic (blue). Will a two-year-old with these defects also be cyanotic? Explain your answer.

Regents for estimation of reducing sugar by fehling soxhlet, Define Regents...

Define Regents for Estimation of Reducing Sugar by Fehling Soxhlet Method? Fehling A solution - copper sulphate solution Fehling B solution - alkaline tartarate so

Explain vitamin k as an essential fat soluble micronutrient, Explain Vitami...

Explain Vitamin K as an essential fat soluble micronutrient? Vitamin K is an essential fat-soluble micronutrient the only unequivocal role in health is in the maintenance of no

Meiosis, What problem would most likely to occur if a haploid cell attempte...

What problem would most likely to occur if a haploid cell attempted to perform meiosis?

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd