Explain lipid formulations, Biology

Assignment Help:

Explain Lipid Formulations

Three lipid formulations of amphotericin B are marketed in the US: amphotericin B lipid complex (ABLC, Abelcet), liposomal amphotericin B (L-AmB, AmBisome), and amphotericin B colloidal dispersion (ABCD, Amphotec). In clinical trials, these formulations have been at least as effective as amphotericin B deoxycholate.

Compared to conventional amphotericin B, acute infusion-related reactions are worse with Amphotec, less with  Abelcet, and least with AmBisome.  Nephrotoxicity is less common with lipid-based products and, when it occurs, less severe than with amphotericin B deoxycholate. Liver toxicity, which is generally not associated with amphotericin B deoxycholate, has been reported with the lipid formulations

 


Related Discussions:- Explain lipid formulations

01.03 new technology, What is the best microscope to get a detailed view of...

What is the best microscope to get a detailed view of the parts inside of a preserved plant cell?

Define the properties of fibre, Define the Properties of Fibre? The str...

Define the Properties of Fibre? The structural make up of fibre influences its properties which in turn affects the physiologic and metabolic roles. This is well-depicted in th

Insulin dependent diabetes mellitus, Q. What is Insulin Dependent Diabetes ...

Q. What is Insulin Dependent Diabetes Mellitus? Mostly children and adolescents suffer from this type of diabetes however; it may appear in adults and elderly too. In this, the

Most abundant form under which nitrogen is found in nature, Q. What is the ...

Q. What is the most abundant form under which nitrogen is found in nature? The major abundant nitrogen-containing molecule found in nature is molecular nitrogen (N2). The air i

Assessment of peripheral vascular perfusion (beside test), Assessment of Pe...

Assessment of Peripheral Vascular Perfusion (Beside Test) Burger's Postural Test Perform in daylight.  Place patient supine with both legs elevated and knees

Post operative anticoagulation, Post Operative Anticoagulation :  Thromboe...

Post Operative Anticoagulation :  Thromboembolism remains a serious complication after valve replacement. Lifelong anticoagulation is requised for all patients with a prosthetic v

Explain flavour binding - protein, Flavour Binding   Some   protein pre...

Flavour Binding   Some   protein preparations, although acceptable from a functional and nutritional stand point, necessitate  a deodorizing step to remove the bound off-flavor

What is parasitism, Q. What is parasitism? The Parasitism is the ecolog...

Q. What is parasitism? The Parasitism is the ecological interaction in which a being lives at the expense of another. The parasite often doesn't cause immediate death of the ho

How do derived characters help cladistic taxonomists, How do derived charac...

How do derived characters help cladistic taxonomists determine phylogenetic relationships? A derived character is found only between members of a particular group. Thus, cladi

Difference between hemoglobin and oxyhemoglobin, Q. How different are hemog...

Q. How different are hemoglobin and oxyhemoglobin? Where is it expected to find a higher concentration of oxyhemoglobin, in peripheral tissues or in the lungs? Oxygen-bou

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd