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Explain Lipid Formulations
Three lipid formulations of amphotericin B are marketed in the US: amphotericin B lipid complex (ABLC, Abelcet), liposomal amphotericin B (L-AmB, AmBisome), and amphotericin B colloidal dispersion (ABCD, Amphotec). In clinical trials, these formulations have been at least as effective as amphotericin B deoxycholate.
Compared to conventional amphotericin B, acute infusion-related reactions are worse with Amphotec, less with Abelcet, and least with AmBisome. Nephrotoxicity is less common with lipid-based products and, when it occurs, less severe than with amphotericin B deoxycholate. Liver toxicity, which is generally not associated with amphotericin B deoxycholate, has been reported with the lipid formulations
Why is a weekly acidic drug best absorbed in an acidic environment?
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Hi,I am a graduating student from my course BS in Biology major in Zoology. I was wondering if you guys have any great idea of a good thesis title?
Blunt or Non-penetrating Injury When body is struck by a blunt object such as steering wheel or blows to chest with blunt object. External injury may appear minor but the
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