Explain itraconazole, Biology

Assignment Help:

Explain Itraconazole

It has a broader spectrum of activity than fluconazole. It is active against a wide variety of fungi including Cryptococcus neoformans, Aspergillus spp., Blastomyces dermatitidis, Coccidioides immitis,  Histoplasma capsulatum,  Paracoccidioides brasiliensis,  Pseudallescheria boydii,  Sporothrix spp., and dermatophytes. It also has good activity against most Candida spp. containing some strains of fluconazole-resistant C. glabrata. Itraconazole has no clinically meaningful activity against Fusarium  spp. or Zygomycetes. Itraconazole  is not recommended for treatment of meningitis because it does not cross the blood-brain barrier.

 


Related Discussions:- Explain itraconazole

Results-types of surgery in ar, Results: Largely depends on the LV functi...

Results: Largely depends on the LV function. In most centres surgical mortality is 3 to 4 percent. For patients with severe LV dysfunction the immediate and late results of sur

Causes of cancer, Causes of Cancer We know earlier that a malignant tu...

Causes of Cancer We know earlier that a malignant tumor is a large aggregation of cancer cells, all of them descended from a single founder cell that was once a normal cell wi

Express the term - amnion, Express the term - Amnion One of the extraem...

Express the term - Amnion One of the extraembryonic membranes found in terrestrial vertebrate. The amnion is filled with fluid and the developing embryo of reptiles, birds, and

What are pioneer species, What are pioneer species? What is the role of the...

What are pioneer species? What is the role of the pioneer species? Pioneer species are those first species that colonize places where before there were no living beings, like,

What are the major cells of the connective tissue proper, Q. What are the m...

Q. What are the major cells of the connective tissue proper? What is the name given to the intercellular material that surrounds these cells? The major cells of the connective

Portal circulation, POR T AL CIRCULATION When a vein branches into se...

POR T AL CIRCULATION When a vein branches into set of capillary to distribute blood in some parts, such venous circulation is called portal system. Three types of portal syst

Difference between the concepts of karyotype and genome, What is the differ...

What is the difference between the concepts of karyotype and genome? Genome is the set of DNA molecules that characterizes each living being or every species. The concept then

Vitamins and minerals requirement in diabetes, Q. Vitamins and minerals req...

Q. Vitamins and minerals requirement in diabetes? The recommendation of vitamins and minerals is the same as for general population. However, lower levels of magnesium are ass

Amount of intracellular chloride ions in neuron a, Amount of intracellular ...

Amount of intracellular chloride ions in neuron A Neuron A is a healthy neuron with all the usual ion channels.  When at rest with a membrane voltage of R millivolts, neuron A

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd