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Explain Itraconazole
It has a broader spectrum of activity than fluconazole. It is active against a wide variety of fungi including Cryptococcus neoformans, Aspergillus spp., Blastomyces dermatitidis, Coccidioides immitis, Histoplasma capsulatum, Paracoccidioides brasiliensis, Pseudallescheria boydii, Sporothrix spp., and dermatophytes. It also has good activity against most Candida spp. containing some strains of fluconazole-resistant C. glabrata. Itraconazole has no clinically meaningful activity against Fusarium spp. or Zygomycetes. Itraconazole is not recommended for treatment of meningitis because it does not cross the blood-brain barrier.
LIPOIDA L MODELS According to Overton (1902) plasma membrane consists of single layer of lipid, because cell permeability is related to lipids. According to Gorter and
Matthew Meselson and Frank Stahl grew bacteria in media having either N14 or N15 for various numbers of cell divisions. DNA from the bacterial samples were isolated and spun within
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ExplainTransketolase Transketolase with the help of TPP and Mg ++ is required again. This time it transfers carbon 1+2 from xylulose-5-phosphate to erythrose-4-phospha
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what is virus ?? what is classidication , uses , disease of viruses ? what are types of virus ?
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