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Explain Itraconazole
It has a broader spectrum of activity than fluconazole. It is active against a wide variety of fungi including Cryptococcus neoformans, Aspergillus spp., Blastomyces dermatitidis, Coccidioides immitis, Histoplasma capsulatum, Paracoccidioides brasiliensis, Pseudallescheria boydii, Sporothrix spp., and dermatophytes. It also has good activity against most Candida spp. containing some strains of fluconazole-resistant C. glabrata. Itraconazole has no clinically meaningful activity against Fusarium spp. or Zygomycetes. Itraconazole is not recommended for treatment of meningitis because it does not cross the blood-brain barrier.
What is Life threatening haemorrhage Life threatening haemorrhage has been reported when a drill perforates the sublingual region of the mandible and injures the sublingual arte
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6. What is the function of the myelin sheath? Do all axons present a myelin sheath?
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