Explain inotropes and vasopressors, Biology

Assignment Help:

Explain Inotropes and Vasopressors

Persisting hemodynamic instability after correction of hypovolemia would necessitate the use of vasoactive agents. Which drug or intervention to use would depend on the type of shock. The clinical effects of available drugs are summarized in table. In cardiogenic shock, characterised by low cardiac output and peripheral vasoconstriction, dobutamine is a good drug to use, as it has inotropic as well as vasodilator effect. Phosphodiesterase inhibitors like milrinone also act in a similar fashion. Pure vasodilators like glyceryl trinitrate and sodium nitroprusside may also help in reducing the peripheral vasoconstriction and thereby, the systemic vascular resistance. Intra-aortic balloon counterpulsation increases coronary blood flow and reduces left ventricular afterload, thus reversing myocardial ischemia and improving cardiac performance. It is useful in patients in whom myocardial revascularization can be accomplished either by surgery or angioplasty and in the postoperative cardiac surgical patient with low cardiac output state. It is less successful in acute myocardial infarction complicated by cardiogenic shock if there is no lesion that can be revscularized.

531_summary of clinical effect.png


Related Discussions:- Explain inotropes and vasopressors

Explain epimerism, Epimerism:- Another type of stereo isomerism known ...

Epimerism:- Another type of stereo isomerism known as epimerism occurs with respect to a single asymmetric carbon atom of a monosaccharide possessing more than one asymmetric

What is computerised tomography, What is Computerised tomography Comput...

What is Computerised tomography Computerised tomography (CT, but also known as computerised axial tomography, or CAT) provides structural images. To generate brain scans, low l

Define age as a determinants of nutrient requirements, Define Age as a dete...

Define Age as a determinants of nutrient requirements? Age: Requirements change with increasing age between birth and maturity. Nutrient requirements per unit body weight are h

Nutrition intervention, Nutrition intervention Nutrition intervention, ...

Nutrition intervention Nutrition intervention, the third step of  the nutrition care process, is a specific set of activities and associated materials used  to address the prob

Explain leptospirosis, Leptospirosis It is a bacterial disease that oc...

Leptospirosis It is a bacterial disease that occurs in many domestic and wild animals, is endemic worldwide, but the highest incidence is in tropical and subtropical areas. Tr

Indications for gingival curettage - endodontic surgery, Indications for Gi...

Indications for Gingival Curettage - Endodontic Surgery a) Persistent periradicular pathosis following endodontic treatment, b) Periradicular lesion that enlarges after endo

Gregor johann mendel, GREGOR JOHANN MENDEL 1.         Mendel was born o...

GREGOR JOHANN MENDEL 1.         Mendel was born on 22 July 1822 at Heizendorf in Austria at Selesia village. 2.         Mendel was worked in Augustion Monastry as monk at Br

Neuropsychological assessment of adults, Neuropsychological assessment of a...

Neuropsychological assessment of adults A general introduction of the field of neuropsychological assessment and deals specifically with the extensive standard test batteries a

Why domain archaea are known to contain a true nucleus, Bacteria never have...

Bacteria never have a nucleus but some members of the domain Archaea are known to contain a true nucleus.

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd