Gonorrhea

Single doses of cefixime (Suprax) orally or ceftriaxone  (Rocephin)  intramuscularly (IM) are highly effective for uncomplicated anogenital or pharyngeal infection, including infection with penicillin- and tetracycline-resistant strains of Neisseria gonorrhoeae.  Cefpodoxime (Vantin)  is another option for oral therapy, although experience is limited. Single-dose treatment with ciprofloxacin (Cipro, and others), ofloxacin or levofloxacin is highly effective when N. gonorrhoeae are susceptible, but strains with clinically significant fluoroquinolone resistance are common worldwide, especially in Asia and the Pacific Islands (including Hawaii), and are increasing in the western United States.