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Galactose Metabolism
Galactose goes to the liver via portal blood and is phosphorylated by galactokinase togalactose- 1 -phosphate (GIP) using ATP as a phosphate donor as shown in Figure. 1 -phosphate reacts with uridine diphosphate glucose to fom uridine diphosphategalactose catalyzed by galactose-I-phosphate uridyl transferuse. It is then convertedto UDP-glucose catalyzed by UDP-galactose 4-epimerase. Since this would be thewell-fed state, the glucose would be incorporated into the glycogen chain through theaction of glycogen synthase.
Explain Conventional Factors ? Smoking, Hypertension, diabetes mellitus, obesity, hypercholesterolemia, and reduced physical activity are considered as conventional risk factor
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