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Explain Entecavir
Entecavir (Baraclude) taken orally once a day as monotherapy appears to be superior to lamivudine for patients with chronic HBV infection, but susceptibility to entecavir may be reduced in patients refractory to lamivudine. How it compares with adefovir remains to be established, but HBV isolates from lamivudine-refractory patients failing entecavir therapy have remained susceptible to adefovir in vitro.
Production of substances interfering with virus proliferation In some cases plants are known to synthesise chemicals that inhibit crucial functions of pathogens. This makes pl
By bombarding atoms in a thin metal sheet with energetic particles, Rutherford found that most of the mass of an atom is concentrated inside a very small volume. What is the diamet
Explain Carbohydrates - Nutritions? Liberal amounts of carbohydrates should be given i.e. around 60% to 65% of the total energy. However, care must be taken regarding the maxim
Define Classification of Lipids? Chemically, lipids are the organic molecules poor in oxygen content, soluble in organic solvents but insoluble in water. They are classified as
Risk Factor Modification : Even after CABG, patients are at risk of progression of native coronary artery disease and development of lesions in the conduits. Modification of
Cidofovir (Vistide) IV cidofovir given once weekly for 2 weeks and then once every 2 weeks for maintenance therapy can delay progression of CMV retinitis in patients with AIDS
Dose-response extrapolation In order to be compared to human exposure levels, the animal data need to be extrapolated to doses much lower than those studied. This extrapolation
Substrates are reagent molecules upon which enzymes act. The enzyme has spatial binding sites for the attachment of its substrate. These sites are known as activation centers of
Q. What are the zymogens? proenzymes, or Zymogens, are enzymes secreted in inactive form. Under some conditions a zymogen shifts to the active form of the enzyme. Zymogen secre
Properties and Functions of Synapses There is an interval between depolarisation of the presynaptic terminal and the earliest appearance of a postsynaptic response. This inter
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