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Motion Sickness
The pathogenesis of motion sickness is poorly under- stood. The prescription cholinergic blocker scopolamine in a patch or oral formulation can decrease symptoms. Transderm Scoop is applied to the skin behind the ear 6-8 hours before exposure and changed every three days. The oral 8-hour tablet (Scopace) is taken 1 hour before exposure. Oral pro- methazine (Phenergan, and others) is a highly sedating alternative. Over-the-counter drugs such as dimenhydrinate (Dramamine, and others) or meclizine (Bonine, and others) are less effective, but may be helpful for milder symptoms.
This species is an ornamental tree in China, and has yielded the clinically active agents topotecan, irinotecan, and 9 -aminocamptothecin, which are semisynthetically derived from
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