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Database Search: Once an open reading frame or the partial amino acid sequence has been pre-determined, the investigator compares sequence with others in the databases using a computer and a search algorithm. This is generally done in a protein database such as PIR or Swiss-Prot. Nucleic acid sequences are in the GenBank and EMBL databases. The search algorithms commonly used are BLAST and FASTA.
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Determine sequence weights for the sequences ACTA, ACTT, CGTT, and AGAT by using Thompson, Higgins, and Gibson method
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