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Explain CORONAW ARTERY DISEASE (CAD)?
As far as CAD is concerned the people of South Asian region are at a very disadvantageous position. The term 'South Asians' includes persons that originated from nations of Indian subcontinent: India, Pakistan, Bangladesh, Nepal, Bhutan and Sri Lanka. They also include large and small immigrant populations residing in different parts of the world. While differing in ethnic and socio-economic characteristics, they share a common characteristic the highest predisposition to develop CAD - and in that the immigrant Indians shares the major burden. Normally CAD rates vary among different populations with first generation immigrants having rates intermediate between that of the country of origin and the host country. The CAD rates ultimately blend with the prevalent rates of the adopted country in two or three successive generations, depending on the rate of acculturation and adoption of lifestyle habits of the host country. While other immigrant communities follow the same pattern, Indian immigrants are singular exception because they have higher rates of CAD than the native population of the adopted country.
The magnitude of the problem can be understood by looking at the prevalence, severity, prematurity and mortality of CAD in South Asians, also called as Asian Indians.
It contain four steps. They are: Attachment to host Proliferation Invasion of host tissue Toxin-induced damage to host cell
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