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Under the limiting oxygen conditions experienced in by vigorous exercise, the configuration of NADH by glycolysis exceeds the ability of the respiratory chain to oxidize it back to NAD+. The pyruvate produced by glycolysis in muscle is then converted to lactate by lactate dehydrogenase, a reaction which regenerates NAD+ and so allows glycolysis to continue to produce ATP. Furthermore, lactate is a metabolic dead-end in which it cannot be metabolized further until it is converted back to pyruvate. The Lactate diffuses out of the muscle and is carried in the bloodstream to the liver. Here it spread into liver cells and is converted back to pyruvate by lactate dehydrogenase. The pyruvate is then transformed to glucose by gluconeogenesis and the glucose is released back into the bloodstream ready to be taken up by skeletal muscle and brain. This cycle of reactions shown in the figure is known as the Cori cycle.
Consider a properly functioning positive feedback system whose output variable is not equal to plateau at 1:00 AM. At 1:00 AM, A. when the value of threshold is greater than t
The clinical manifestations of IE result from the local destructive effects of intracardiac infection; the embolization of bland or septic fragments of vegetations to
Hypodermic-Subcutaneous Injection By this route the drug is mainly absorbed into the blood stream by way of the lymphatic drainage. Absorption is slower by this route
List the two primary targets to assess the good sugar control 1) There are two primary targets to assess the effectiveness of the management plan on glycemic (sugar) controls.
Which of the following serves as an actuating signal, or as part of an actuating signal, in a positive feedback system? A. Blood plasma levels of PTH (Parathryroid Hormone).
how to explain the structure and function of the organelle
GENERAL PREVENTIVE MEASURES - 1. Infected animal should be immediately isolated and looked after. 2. The premises should be disinfected whenever there is an outbre
Define Drug effects on Metabolism of dietary components? Drugs can also compete with, or inhibit, the metabolic conversion of some micronutrients to their active metabolites,
Degradation of Ecosystem Ancient man was simple-minded food gatherer and hunter. He looked upon nature with awe and respect and in fact he worshipped it. But from the time he
Follow a cell through the cell cycle. How many copies of each gene are present at each stage?
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