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Conservative Substitution: The nucleotide mutation that alters the amino acid sequence of protein, but which causes substitution of one amino acid with another which has a side chain with the similar charge/polarity characteristics. The size of the side chain might also be a significant consideration. Conservative mutations are usually considered unlikely to profoundly alter the structure or the function of a protein, but there are number of exceptions.
Microorganisms and Plants can synthesize all of the 20 standard amino acids. Mammals, furthermore, cannot synthesize all 20 and must obtain some of them in their diet. Those amin
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Less than ideal Primary Stability Faulty osteotomy (a bigger osteotomy than required for the selected diameter of implant) can result when excessive force is used to disengage
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