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Explain citric acid cycle
In the citric acid cycle, the oxaloacetate is first condensed with acetyl CoA, and then regenerated as the cycle is comp!eted. But these reactions are not part of a closed circle system and are more similar to a traffic circle with compounds entering and leaving as required. Only a small quantity of oxaloacetate is needed for the oxidation of a large quantity of acetyl CoA, as it is regenerated. Hence, oxaloacetate may be considered to play a catalytic role.
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Phylogenetic considerations
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