Explain bone physiology and wound healing, Biology

Assignment Help:

Bone Physiology and Wound Healing

The events involved in osseous wound healing around implants recapitulate the events of wound healing which is depicted in the flowchart.

26_biology.png

The effect of many inflammatory mediators, eicosanoids, interleukins and is it chemokines  on bone formation and osteoblast behaviour in culture strongly implicates the implication of post surgical inflammatory processes in determination of bone formation.

After the establishment of a well vascularised, immature connective tissue, osteogenesis continues by the recruitment, proliferation and differentiation of the osteoblastic cells. Differentiated osteoblast secretes a collagenous matrix and contributes to its mineralization.

Eventually during the formation, the matrix surrounds the osteoblastic cells and mineralization of a collagenous rich matrix is completed. This cell rich and unorganized bone is called woven bone. The transformation of woven bone to lamellar bone i.e. bone organized to resist physical strain and displaying a haversian architecture, is another important part of osseointegration. Thus, osseointegration involves the direct bone apposition on the implant surface followed by the structural adaptation of the bone to mechanical load and represents a lifelong process of bone formation, adaptation to function and repair of bone

 

 


Related Discussions:- Explain bone physiology and wound healing

What are immunoglobulins, Q. What are immunoglobulins? Immunoglobulin i...

Q. What are immunoglobulins? Immunoglobulin is the alternate name given to antibody and Immunoglobulins are complex proteins containing a variable portion and an invariable por

What are all possibilities of genotypes and phenotypes, What are all possib...

What are all possibilities of genotypes and phenotypes formed in the combination of alleles responsible for the production of factor VIII? Considering the alleles X and Xh, whe

Explain the micronutrients requirements during sepsis, Explain the Micronut...

Explain the Micronutrients Requirements during Sepsis Micronutrients: The requirement of almost all vitamins and certain mineral increases due to infection and inflammation. In

What is the autotrophic hypothesis on the origin of life, What is the autot...

What is the autotrophic hypothesis on the origin of life? The autotrophic hypothesis on the origin of life asserts that the first living beings on earth were producers of thei

Determine about the chloroplast, Determine about the Chloroplast One of...

Determine about the Chloroplast One of the most distinguishing features of all eukaryotic plant cells is that in addition to mitochondria, they contain special light harvesting

What is large intestine in human biology, What is Large Intestine in human ...

What is Large Intestine in human biology? Food undigested in the small intestine is passed on by peristalsis into the large intestine, or colon. The intestine is composed of ci

How green leaves make food for plants, Green leaves make food for plants ...

Green leaves make food for plants Heat some alcohol in a jar over boiling water unless it boils. Break various green leaves from a geranium or other plant which has been in the

Define the drugs effects on excretion, Define the Drugs Effects on Excretio...

Define the Drugs Effects on Excretion? Use of certain drugs can influence the excretion of certain substances. For example, besides their intended increase in sodium excretion,

Is the ventricle lumen larger during diastole, Q. Is the ventricle lumen la...

Q. Is the ventricle lumen larger during diastole or during systole? During diastole the opposite occurs. The muscle fibers of the ventricles relax and the lumen of these chambe

How is the skin involved in the regulation of temperature, Q. How is the sk...

Q. How is the skin involved in the regulation of body temperature? Skin is one of various organ systems participating in maintaining a core temperature, meaning the temperature

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd