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Bacterial vaginosis
The role of sexual transmission is unclear in bacterial vaginosis, in which normal H2O2-producing Lactobacillus species are replaced by overgrowth with Gardnerell vaginalis, M. hominis, Mobiluncus and various anaerobes. Oral metron- idazole for 7 days is usually effective for treatment. Single-dose oral metronidazole has similar short-term efficacy, but is followed by a higher rate of relapse. Vaginal metronidazole, or oral or vaginal clindamycin, are also effective. With any regimen, recurrence is common; re-treatment with the same agent is often effective. Treatment of sex partners does not reduce the frequency of recurrence.
In the early days of microbiology, the disease producing submicroscopic agents were termed as 'filterable viruses' because of their ability to pass through conventional filters whi
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