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Explain Adverse Effects of ganciclovir
Ganciclovir is teratogenic, carcinogenic and mutagenic and causes aspermatogenesis in animals. Granulocytopenia and thrombocytopenia, which are usually reversible, are more common with the IV formulation. Severe myelosuppression may occur more frequently when the drug is given concurrently with zidovudine. Granulocyte-colony-stimulating factors (GM-CSF; G-CSF) have been used to treat ganciclovir-induced neutropenia.
Define Fluconazole It is a weaker inhibitor of CYP3A4 than itraconazole or ketoconazole but may still increase serum concentrations of drugs metabolized by 3A4, like cyclospor
NAILS - Cover terminal segment of fingers & toes. Highly vascular dermis under lying the nail is called nail bed . It gives pinkish colour to nail. The small part
Expressed sequence tag (EST) is the short part of DNA sequence of corresponding to the fragment of the complementary DNA (made from the cell's messenger RNA). ESTs have been taken
SMAL L INTESTINE - A narrow tube 6 m long. In rabbit 4 m. long.Differentiated into duodenum, jejunum & Ileum. (i) Duodenum - 2.5 cm long. C-shaped (U-shaped in rabbit)
Hydrogen bonds are important for all of the following except:: a) Allowing carbohydrates to dissolve in water b) Stabilizing the three-dimensional shape of proteins. c) Ma
how can i explain the biphasic graph i get fom combination of two drugs?
Polarity in Regeneration A distinct polarity or gradient exists in planarians (and in other animals). The meaning of this is that in any piece or segment of the body; its ant
1. By direct measurement of the activity of the thyroid gland in several patients who had received 131 I for diagnostic purposes, it was observed that the biological elimination h
What is Simple Transposition in Neonates ? A baby with this malformation needs to be operated without delay. A very cyanosed infant will require palliation by balloon arteries
Q. Differentiate between adult and infant botulism? • Adult Botulism is prevalent amongst adults whereas Infant Botulism is prevalent in infants of less than one year of age.
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