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Explain Adverse Effects of Cidofovir
About 25% of patients discontinue cidofovir because of adverse effects such as nephrotoxicity, neutropenia and metabolic acidosis. Iritis, uveitis or ocular hypotony can happen. To decrease the risk of nephrotoxicity, IV 0.9% saline and oral probenecid must be given with each cidofovir dose. Cidofovir is contraindicated in patients taking other nephrotoxic agents. Adverse effects are more common in patients at the same time taking antiretroviral drugs. The drug is oncogenic in animals. Topical cidofovir (not commercially available) causes local irritation and ulceration, especially in concentrations of 3% or higher.
The most recent blood work of a patient with a diagnosis of acute myelogenous leukemia (AML) reveals thrombocytopenia. Where is the patient most likely to experience abnormal bleed
C h oice of transgenic animal First and foremost is the selection of animal species in which gene of interest is to be transferred. Whatever is the goal of production of tran
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Why is a weekly acidic drug best absorbed in an acidic environment?
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Who was Charles Darwin? Charles Darwin was an English naturalist born in 1809 and considered the father of the theory of evolution. At the end of the year 1831, before turning 23
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