Explain adverse effects of cidofovir, Biology

Assignment Help:

Explain Adverse Effects of Cidofovir

About 25% of patients discontinue cidofovir because of adverse effects such as nephrotoxicity, neutropenia and metabolic acidosis. Iritis, uveitis or ocular hypotony can happen. To decrease the risk of nephrotoxicity, IV 0.9% saline and oral probenecid must be given with each cidofovir dose. Cidofovir is contraindicated in patients taking other nephrotoxic agents. Adverse effects are more common in patients at the same time taking antiretroviral drugs. The drug is oncogenic in animals. Topical cidofovir (not commercially available) causes local irritation and ulceration, especially in concentrations of 3% or higher.

 


Related Discussions:- Explain adverse effects of cidofovir

Name the source gland of leutinising hormone, Name the source gland of leut...

Name the source gland of leutinising hormone (LH). State the other hormone along with which it acts on its target cells/organ. Give their two functions.

Parasitic protozoan, Parasitic Protozoan Out of the thousands of speci...

Parasitic Protozoan Out of the thousands of species of Protozoa, the majority are free living. However, many species from within the phyla Sarcomastigophora and Ciliophora are

Understanding life, UNDERS T ANDIN G LIF E - Presence of proto...

UNDERS T ANDIN G LIF E - Presence of protoplasm is the important feature of life which acts the site of metabolism. Maintenance of life by protoplasm requires conti

Clinical features - infective endocarditis, The clinical  manifestations of...

The clinical  manifestations of IE result from the local destructive effects of intracardiac infection; the embolization of bland or septic fragments of vegetations to

Pedigree charts, How do I complete a pedigree chart for genetics?

How do I complete a pedigree chart for genetics?

Explain the components of heart sounds, Explain the Components of heart sou...

Explain the Components of heart sounds? The first major component is associated with mitral valve closure (M 1) and is due to abrupt arrest of the leaflet motion when the cusps

What is the life duration of the red blood cells, Q. On average what is the...

Q. On average what is the life duration of the red blood cells? Where are they destroyed? What is the destination of the heme groups after the destruction of hemoglobin molecules?

#title.germ cell development, Ask questionhow are germ cells immortal #Mini...

Ask questionhow are germ cells immortal #Minimum 100 words accepted#

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd