Explain adverse effects of cidofovir, Biology

Assignment Help:

Explain Adverse Effects of Cidofovir

About 25% of patients discontinue cidofovir because of adverse effects such as nephrotoxicity, neutropenia and metabolic acidosis. Iritis, uveitis or ocular hypotony can happen. To decrease the risk of nephrotoxicity, IV 0.9% saline and oral probenecid must be given with each cidofovir dose. Cidofovir is contraindicated in patients taking other nephrotoxic agents. Adverse effects are more common in patients at the same time taking antiretroviral drugs. The drug is oncogenic in animals. Topical cidofovir (not commercially available) causes local irritation and ulceration, especially in concentrations of 3% or higher.

 


Related Discussions:- Explain adverse effects of cidofovir

Immobilisation of cells, Immobilisation of cells Immobilisation of cel...

Immobilisation of cells Immobilisation of cells enables Re-use of biomass by rotation of cells Separation of cells from the medium and Leaching of metab

Define the term - functional magnetic resonance imaging, Define the term - ...

Define the term - Functional magnetic resonance imaging Functional magnetic resonance imaging (fMRI) is a recent development that permits simultaneous measurements of the brain

To show the direction of sprout growth in seeds, To show the direction of s...

To show the direction of sprout growth in seeds Soak pumpkin or other large seeds overnight and fasten three of them on needles as shown in the diagram. Fasten single with the

The accident or incident theory - accident causation, The Accident or Incid...

The Accident or Incident Theory - Accident Causation Peterson when reiterating the significance of human factors added such factors as ergonomic traps, the decision to err and

Nursing care of common cold, Nursing Care of Common Cold: Relieve Nas...

Nursing Care of Common Cold: Relieve Nasal Congestion Clean the nasal passage to remove secretions. In  infants nasal aspirator can be used while  the older children can

Determine the symptoms of cholera, Determine the Symptoms of Cholera  A...

Determine the Symptoms of Cholera  An infective dose of around one million organisms should be ingested to cause illness. The bacteria adhere to the small intestine wall, where

Which type of gamete do the male respectively produce, Concerning the sex c...

Concerning the sex chromosomes of the XY system which type of gamete do the male and the female individuals respectively produce? The individual of the male sex is XY so he for

Provide evidence to explain the conversion, Provide supporting evidence to ...

Provide supporting evidence to explain how conversion of a normal somatic cell into a malignant one requires multiple mutations.

Define symptoms in stomach and mouth of pernicious anaemia, Define symptoms...

Define symptoms in Stomach and Mouth of pernicious anaemia? Stomach: The cells which secrete acid and enzymes are atrophied. The gastric secretions are devoid of acid, pepsin

Neuropsychological assessment of adults, Neuropsychological assessment of a...

Neuropsychological assessment of adults A general introduction of the field of neuropsychological assessment and deals specifically with the extensive standard test batteries a

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd