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Explain Adverse effects of Amprenavir
The most common adverse effects have been nausea, vomiting (especially in combination with zidovudine), perioral paresthesias and rash (JC Goodgame et al, Antivir Ther 2000; 5:215). Many patients with rash can continue or restart amprenavir if the rash is mild or moderate, but about 1% of patients have developed severe rashes, including Stevens-Johnson syndrome.
A codon comprise three nucleotides. There are four possible nucleotides, each of which has an equal probability of being in any one of three spots. How many possible codons exist?
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