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Bacteria:-
Advantages
High yield of protein (60-80%) Can be grown on paraffin, cellulose waste and molasses.
Growth rate is fast.
Disadvantages
If the bacterial strain is very small in size and of low density, separation from the culture media is difficult.
Bacteria have a high nucleic acid content (>15%) and may come over along with proteins, which is not acceptable and not required as it can cause hypertension, arthritis etc.
Uric acid, the final product of purine metabolism, may lead to gout.
In a properly functioning negative feedback system, the A. value of the controlled variable will always be very close to the threshold value when the system is in steady state.
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